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Medications for Bipolar Disorder

The medications listed below are related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
lamotrigine 8.1 1083 reviews for lamotrigine to treat Bipolar Disorder Rx C N X
Generic name:
lamotrigine systemic
Brand names:
Lamictal, Lamictal ODT, Lamictal CD, Subvenite
Drug class:
triazine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
lurasidone 6.3 721 reviews for lurasidone to treat Bipolar Disorder Rx B N X
Generic name:
lurasidone systemic
Brand name:
Latuda
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
quetiapine 7.1 712 reviews for quetiapine to treat Bipolar Disorder Rx C N X
Generic name:
quetiapine systemic
Brand names:
Seroquel, Seroquel XR
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Latuda 6.3 669 reviews for Latuda to treat Bipolar Disorder Rx B N X
Generic name:
lurasidone systemic
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Lamictal 8.2 663 reviews for Lamictal to treat Bipolar Disorder Rx C N X
Generic name:
lamotrigine systemic
Drug class:
triazine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
aripiprazole 5.7 447 reviews for aripiprazole to treat Bipolar Disorder Rx C N X
Generic name:
aripiprazole systemic
Brand names:
Abilify, Abilify Maintena, Abilify Asimtufii, Abilify MyCite
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
cariprazine 6.1 433 reviews for cariprazine to treat Bipolar Disorder Rx N X
Generic name:
cariprazine systemic
Brand name:
Vraylar
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Seroquel 6.8 408 reviews for Seroquel to treat Bipolar Disorder Rx C N X
Generic name:
quetiapine systemic
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Vraylar 6.0 389 reviews for Vraylar to treat Bipolar Disorder Rx N X
Generic name:
cariprazine systemic
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
lithium 7.3 356 reviews for lithium to treat Bipolar Disorder Rx D N X
Generic name:
lithium systemic
Brand name:
Lithobid
Drug class:
antimanic agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Abilify 5.7 353 reviews for Abilify to treat Bipolar Disorder Rx C N X
Generic name:
aripiprazole systemic
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
olanzapine 6.4 323 reviews for olanzapine to treat Bipolar Disorder Rx C N X
Generic name:
olanzapine systemic
Brand name:
Zyprexa
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
ziprasidone 5.8 300 reviews for ziprasidone to treat Bipolar Disorder Rx C N X
Generic name:
ziprasidone systemic
Brand name:
Geodon
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
divalproex sodium 6.5 279 reviews for divalproex sodium to treat Bipolar Disorder Rx D N X
Generic name:
divalproex sodium systemic
Brand names:
Depakote, Depakote ER
Drug class:
fatty acid derivative anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
asenapine 7.2 252 reviews for asenapine to treat Bipolar Disorder Rx C N X
Generic name:
asenapine systemic
Brand name:
Saphris
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Geodon 5.6 242 reviews for Geodon to treat Bipolar Disorder Rx C N X
Generic name:
ziprasidone systemic
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Saphris 7.3 231 reviews for Saphris to treat Bipolar Disorder Rx C N X
Generic name:
asenapine systemic
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Depakote 6.2 190 reviews for Depakote to treat Bipolar Disorder Rx D N X
Generic name:
divalproex sodium systemic
Drug class:
fatty acid derivative anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
risperidone 6.1 183 reviews for risperidone to treat Bipolar Disorder Rx C N X
Generic name:
risperidone systemic
Brand names:
Risperdal, Risperdal Consta, Rykindo
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Zyprexa 6.4 173 reviews for Zyprexa to treat Bipolar Disorder Rx C N X
Generic name:
olanzapine systemic
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
oxcarbazepine Off-label 8.2 170 reviews for oxcarbazepine to treat Bipolar Disorder Rx C N X
Generic name:
oxcarbazepine systemic
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
gabapentin Off-label 8.5 144 reviews for gabapentin to treat Bipolar Disorder Rx C N X
Generic name:
gabapentin systemic
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
topiramate Off-label 7.1 132 reviews for topiramate to treat Bipolar Disorder Rx D N X
Generic name:
topiramate systemic
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
lumateperone 7.0 129 reviews for lumateperone to treat Bipolar Disorder Rx N X
Generic name:
lumateperone systemic
Brand name:
Caplyta
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Caplyta 7.0 126 reviews for Caplyta to treat Bipolar Disorder Rx N X
Generic name:
lumateperone systemic
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information

Frequently asked questions

View more FAQ

Topics under Bipolar Disorder

Learn more about Bipolar Disorder

Care guides

Symptoms and treatments

Medicine.com guides (external)

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.