Saphris Interactions
There are 649 drugs known to interact with Saphris (asenapine), along with 14 disease interactions, and 4 alcohol/food interactions. Of the total drug interactions, 109 are major, 536 are moderate, and 4 are minor.
- View all 649 medications that may interact with Saphris
- View Saphris alcohol/food interactions (4)
- View Saphris disease interactions (14)
Most frequently checked interactions
View interaction reports for Saphris (asenapine) and the medicines listed below.
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- Ambien (zolpidem)
- Ativan (lorazepam)
- buspirone
- clonazepam
- clonidine
- Cymbalta (duloxetine)
- gabapentin
- hydroxyzine
- Klonopin (clonazepam)
- Lamictal (lamotrigine)
- lamotrigine
- Latuda (lurasidone)
- levothyroxine
- Lexapro (escitalopram)
- lisinopril
- lithium
- melatonin
- metformin
- omeprazole
- prazosin
- propranolol
- Prozac (fluoxetine)
- Seroquel (quetiapine)
- Topamax (topiramate)
- trazodone
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zoloft (sertraline)
Saphris alcohol/food interactions
There are 4 alcohol/food interactions with Saphris (asenapine).
Saphris disease interactions
There are 14 disease interactions with Saphris (asenapine) which include:
- severe hepatic impairment
- dementia
- QT Prolongation
- NMS
- aspiration
- seizure
- hematologic abnormalities
- hyperglycemia/diabetes
- hypotension
- lipid alterations
- weight gain
- depression
- hyperprolactinemia
- tardive dyskinesia
More about Saphris (asenapine)
- Saphris consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (318)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Generic availability
- FDA approval history
- Drug class: atypical antipsychotics
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.