Ibuprofen Alternatives Compared
| Ibuprofen | Tramadol | Gabapentin |
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| Ibuprofen | Tramadol | Gabapentin |
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Prescription and OTC
Ibuprofen is effective for the short-term relief of minor aches and pains and also reduces inflammation. The risk of stomach-related side effects is about half that seen with aspirin although the... View more |
Prescription only
Tramadol is a strong pain relief medicine effective for both general and nerve-related pain. Tramadol can cause dependence and use may be limited by side effects such as nausea and... View more |
Prescription only
Gabapentin may be used in the treatment of partial-onset seizures and nerve pain but is likely to cause dizziness or drowsiness. Gabapentin enacarbil (brand name Horizant), a prodrug of gabapentin... View more |
Related suggestions Chronic Pain
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| More about Ibuprofen | More about Tramadol | More about Gabapentin | ||||||||||||||||||||||||
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Ibuprofen has an average rating of 7.3 out of 10 from a total of 236 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 19% reported a negative effect. |
Tramadol has an average rating of 6.9 out of 10 from a total of 1833 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 24% reported a negative effect. |
Gabapentin has an average rating of 7.1 out of 10 from a total of 2482 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 21% reported a negative effect. |
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See also: ibuprofen side effects in more detail. |
See also: tramadol side effects in more detail. |
See also: gabapentin side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all ibuprofen prices |
View all tramadol prices |
View all gabapentin prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| A-G Profen, Actiprofen, Addaprin, Advil, Advil Children's, Advil Film-Coated, Advil Infant's Concentrated Drops, Advil Junior Strength, Advil Liqui-Gels, Advil Migraine, Caldolor, Cap-Profen, Children's ElixSure IB, Children's Motrin, Childrens Ibuprofen Berry, Genpril, Help I Have An Aching Body, IBU-200, Midol IB, Midol Maximum Strength Cramp Formula, Motrin, Motrin Childrens, Motrin IB, Motrin Infant Drops, Motrin Junior Strength, Motrin Migraine Pain, Motrin Pediatric, NeoProfen, Nuprin, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Proprinal View more | ConZip, Qdolo, Tramadol Hydrochloride ER | Fanatrex, Gabarone, Gralise, Neurontin | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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4 hours |
5.2 hours |
6 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
Prior To 30 Weeks Gestation
Category D
Positive evidence of risk
Starting At 30 Weeks Gestation See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 389 drugs are known to interact with ibuprofen:
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A total of 655 drugs are known to interact with tramadol:
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A total of 266 drugs are known to interact with gabapentin:
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| First Approval Date | ||||||||||||||||||||||||||
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September 19, 1974 |
March 03, 1995 |
December 30, 1993 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.