Comparing Prilosec vs Ranitidine

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Prilosec (omeprazole)	Ranitidine	Enter another drug to compare

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Prilosec (omeprazole)	Ranitidine	Enter another drug to compare
Prescription only Prilosec decreases stomach acid production which promotes the healing of gastric and duodenal ulcers and other inflamed gastrointestinal tissue areas. The risk of interactions with Prilosec is... View more	Prescription and OTC Ranitidine was an acid-suppressing agent that was used to treat a wide range of gastric-acid-related disorders, including gastric ulcers, heartburn, and GERD. Headaches were the most common side... View more	Related suggestions GERD Omeprazole Pantoprazole Nexium Famotidine Protonix Dexilant Stomach Ulcer Omeprazole Pantoprazole Sucralfate Protonix Carafate Famotidine Indigestion Omeprazole Famotidine Prilosec OTC Pepto-Bismol Pepcid Pepcid AC Erosive Esophagitis Omeprazole Pantoprazole Nexium Protonix Famotidine Dexilant Popular comparisons Prilosec vs omeprazole Prilosec vs famotidine Prilosec vs pantoprazole Prilosec vs Protonix Prilosec vs Nexium Prilosec vs Pepcid
More about Prilosec (omeprazole)	More about Ranitidine
Ratings & Reviews
Prilosec has an average rating of 6.9 out of 10 from a total of 54 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 20% reported a negative effect.	Ranitidine has an average rating of 7.2 out of 10 from a total of 163 ratings on Drugs.com. 66% of reviewers reported a positive effect, while 21% reported a negative effect.
View all 54 reviews	View all 163 reviews
Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.
Anxiety (7.4%) Nausea (5.6%) Pain (5.6%) View all Prilosec side effects	Nausea (8.0%) Dizziness (3.7%) Headaches (3.7%) Bloating (3.1%) Swelling (3.1%) Upset stomach (3.1%) Vomiting (3.1%) View all Ranitidine side effects
Drug Class
Proton pump inhibitors	H2 antagonists
Generic Availability
No lower cost generic approved	Lower cost generic
Pricing and Coupons * Prices are without insurance
We could not find an exact match for this medicine. Try searching the Price Guide directly.	We could not find an exact match for this medicine. Try searching the Price Guide directly.
Get free Discount Card	Get free Discount Card

Dosage Forms
Oral delayed release capsule Oral powder for reconstitution, delayed release	Injectable solution Oral capsule Oral syrup Oral tablet
Brand Names
Other omeprazole brands include: Omesec, Prilosec OTC	Acid Control 150, Acid Control 75, Acid Reducer, Acid Reducer Non-Prescription Strength, Acid Relief, Berkley and Jensen Acid Reducer Maximum Strength, Careone Acid Reducer, Deprizine, Equaline Heartburn Relief, Sunmark Acid Reducer Maximum Strength View more
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.
1.5 hours	2.5 hours
CSA Schedule ¹ View glossary of CSA terms
N Not a controlled drug Is not subject to the Controlled Substances Act.	N Not a controlled drug Is not subject to the Controlled Substances Act.
Pregnancy Category
C Category C Risk cannot be ruled out See the full pregnancy warnings document.	B Category B No proven risk in humans See the full pregnancy warnings document.
Drug Interactions
A total of 243 drugs are known to interact with Prilosec: 25 major drug interactions (66 brand and generic names) 170 moderate drug interactions (1322 brand and generic names) 48 minor drug interactions (273 brand and generic names)	A total of 151 drugs are known to interact with Ranitidine: 12 major drug interactions (38 brand and generic names) 72 moderate drug interactions (271 brand and generic names) 67 minor drug interactions (669 brand and generic names)
Alcohol/Food/Lifestyle Interactions
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.	No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
Disease Interactions
C. diff Bone fractures Hypomagnesemia	GI bleeding Porphyria Hemodialysis Liver disease PKU Renal dysfunction
First Approval Date
September 14, 1989	June 09, 1983
WADA Class View classifications
N/A	N/A
More Information
Side effects Drug interactions Dosage Pricing and coupons Pregnancy warnings Breastfeeding warnings Drug images Support group En español	Side effects Drug interactions Dosage Pregnancy warnings Breastfeeding warnings Drug images Support group
Patient Resources
Prilosec uses	Ranitidine uses
Professional Resources
Prescribing information	Prescribing information
Related Treatment Guide
Barrett's Esophagus Erosive Esophagitis GERD Duodenal Ulcer Helicobacter Pylori Infection Indigestion Multiple Endocrine Adenomas Stomach Ulcer Systemic Mastocytosis Zollinger-Ellison Syndrome show all	GERD Erosive Esophagitis Gastric Ulcer Maintenance Treatment Cutaneous Mastocytosis Duodenal Ulcer Duodenal Ulcer Prophylaxis Eczema Gastrointestinal Hemorrhage Hiatal Hernia Indigestion Laryngopharyngeal Reflux Pathological Hypersecretory Conditions Stomach Ulcer Stress Ulcer Prophylaxis Surgical Prophylaxis Urticaria Zollinger-Ellison Syndrome show all

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Prilosec vs Ranitidine

See also:

Protonix

Nexium

Ozempic

Prevacid

Dexilant

Aciphex

Prilosec OTC

Dexlansoprazole

Rabeprazole

Lansoprazole

Further information

Comparing Prilosec vs Ranitidine

See also:

Further information

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