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Medications for Systemic Mastocytosis

Other names: Mastocytosis, Systemic; Systemic Mast Cell Disease

About Systemic Mastocytosis

Systemic mastocytosis is a disorder where there is an increased number of mast cells within the skin, bone marrow and organs such as liver, spleen, lymph nodes and gastrointestinal tract. The symptom severity varies from being mild to life threatening depending on parts of the body that are affected. Symptoms can include skin reactions, blood disorders, swollen spleen, liver or lymph nodes also gastrointestinal effects such as diarrhea, nausea or vomiting.

Drugs used to treat Systemic Mastocytosis

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
cromolyn 6.4 7 reviews
Rx B N

Generic name: cromolyn systemic

Brand name:  Gastrocrom

Drug class: mast cell stabilizers

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Gastrocrom 6.7 3 reviews
Rx B N

Generic name: cromolyn systemic

Drug class: mast cell stabilizers

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Gleevec Rate Add review
Rx D N

Generic name: imatinib systemic

Drug class: BCR-ABL tyrosine kinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

omeprazole Rate Add review
Rx/OTC C N

Generic name: omeprazole systemic

Brand name:  Prilosec

Drug class: proton pump inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

imatinib Rate Add review
Rx D N

Generic name: imatinib systemic

Brand name:  Gleevec

Drug class: BCR-ABL tyrosine kinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Prilosec Rate Add review
Rx C N

Generic name: omeprazole systemic

Drug class: proton pump inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

lansoprazole Rate Add review
Rx/OTC B N

Generic name: lansoprazole systemic

Brand names:  Prevacid, Prevacid OTC, Prevacid SoluTab

Drug class: proton pump inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

midostaurin 8.3 3 reviews
Rx N

Generic name: midostaurin systemic

Brand name:  Rydapt

Drug class: multikinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Rydapt 7.5 2 reviews
Rx N

Generic name: midostaurin systemic

Drug class: multikinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Prevacid Rate Add review
Rx B N

Generic name: lansoprazole systemic

Drug class: proton pump inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Prevacid OTC Rate Add review
OTC B N

Generic name: lansoprazole systemic

Drug class: proton pump inhibitors

For consumers: dosage, interactions, side effects

Prevacid SoluTab Rate Add review
Rx B N

Generic name: lansoprazole systemic

Drug class: proton pump inhibitors

For consumers: dosage, interactions, side effects

Learn more about Systemic Mastocytosis

Mayo Clinic Reference

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription Only.
OTC Over the Counter.
Rx/OTC Prescription or Over the Counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.