Cromolyn Dosage
Medically reviewed by Drugs.com. Last updated on Sep 12, 2024.
Applies to the following strengths: 20 mg/mL; 10 mg/mL; 0.8 mg/inh; 100 mg
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Asthma - Maintenance
Administer 20 mg (1 vial) via nebulizer 4 times a day at regular intervals
Prophylaxis of acute bronchospasm due to exercise, exposure to cold dry air, or environmental allergens: 20 mg (1 vial) via nebulizer shortly before anticipated exposure
Comments:
- This drug is a prophylactic agent to be used in patients whose symptoms are sufficiently frequent to require a continuous regimen of medications; the effect is usually evident after several weeks, although some patients show an almost immediate response.
- This drug should not be added to a therapeutic regimen during an acute episode; therapy should be started once asthma is controlled, the airway is cleared, and the patient is able to inhale adequately.
Use: For the management of bronchial asthma
Usual Adult Dose for Systemic Mastocytosis
Initial dose: 200 mg (2 ampules) orally one-half hour before meals and at bedtime
- If satisfactory control is not achieved within 2 to 3 weeks, may increase dose.
Maximum dose: 40 mg/kg/day
Comment:
- Use of this product has been associated with improvement in diarrhea, flushing, headaches, vomiting, urticaria, abdominal pain, nausea, and itching in some patients.
Use: For the management of patients with mastocytosis.
Usual Pediatric Dose for Asthma - Maintenance
Age: 2 years or older:
Administer 20 mg (1 vial) via nebulizer 4 times a day at regular intervals
Prophylaxis of acute bronchospasm due to exercise, exposure to cold dry air, or environmental allergens: 20 mg (1 vial) via nebulizer shortly before anticipated exposure
Comments:
- This drug is a prophylactic agent to be used in patients whose symptoms are sufficiently frequent to require a continuous regimen of medications; the effect is usually evident after several weeks, although some patients show an almost immediate response.
- This drug should not be added to a therapeutic regimen during an acute episode; therapy should be started once asthma is controlled, the airway is cleared, and the patient is able to inhale adequately.
Use: For the management of bronchial asthma
Usual Pediatric Dose for Systemic Mastocytosis
Age: 2 to 12 years old:
Initial dose: 100 mg (1 ampule) orally one-half hour before meals and at bedtime
Age: 13 years or older:
Initial dose: 200 mg (2 ampules) orally one-half hour before meals and at bedtime
- If satisfactory control is not achieved within 2 to 3 weeks, may increase dose to no more than 40 mg/kg/day.
Maximum dose: 40 mg/kg/day
Comment:
- Use of this product has been associated with improvement in diarrhea, flushing, headaches, vomiting, urticaria, abdominal pain, nausea, and itching in some patients.
- Not recommended for patients less than 2 years of age unless the potential benefits clearly outweigh the risks.
Use: For the management of patients with mastocytosis.
Renal Dose Adjustments
Use with caution; consider decreasing oral dose in patients with renal impairment.
Liver Dose Adjustments
Use with caution; consider decreasing oral dose in patients with hepatic impairment.
Precautions
Safety and efficacy have not been established in patients younger than 2 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
Orally:
- Take orally 30 minutes before meals and at bedtime.
- Oral liquid is supplied in ampules (100 mg/5 mL) for oral use only; not for inhalation or injection.
- At time of use, break open ampule(s) and squeeze contents into a glass of water; drink all liquid.
Nebulizer:
- Administer via nebulization 4 times a day.
- Solution for nebulization is supplied in vials (20 mg/2 mL) for oral inhalation only; not for injection.
- This drug should be administered via a power driven nebulizer at an airflow of 6 to 8 L/min with a suitable face mask; hand-operated nebulizers are not suitable for administration.
Storage requirements:
- Protect from light; store vials/ampules in foil pouches until ready to use
- Do not use if the solution is discolored or contains a precipitate.
- Stability and safety of this drug when mixed with other drugs in a nebulizer have not been established.
General:
- This is a prophylactic agent and has no role in the acute treatment of asthma.
- Effectiveness is dependent upon administration at regular intervals.
Monitoring:
- Monitor for control of symptoms; once symptoms are controlled, dose may be reduced to the minimum required to maintain the patient with a lower degree of symptomatology.
Patient advice:
- Patients should understand that this drug is a preventative agent, it may take 2 to 4 weeks to see benefit; effectiveness is dependent on regular administration.
- Patients with acute symptoms should seek medical advice promptly.
More about cromolyn
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (29)
- Side effects
- During pregnancy
- Drug class: mast cell stabilizers
- Breastfeeding
Patient resources
- Cromolyn sodium drug information
- Cromolyn sodium inhalation
- Cromolyn (Inhalation) (Advanced Reading)
- Cromolyn (Oral) (Advanced Reading)
- Cromolyn Capsules
- Cromolyn Oral Concentrate
Other brands
Gastrocrom, Intal Inhaler, Intal
Professional resources
- Cromolyn (Systemic, Oral Inhalation) monograph
- Cromolyn Sodium (FDA)
- Cromolyn Sodium Inhalation Solution (FDA)
Other brands
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Further information
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