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Cromolyn sodium (inhalation)

Generic name: cromolyn sodium (inhalation) [ KROE-moe-lin-SOE-dee-um ]
Dosage form: inhalation solution (10 mg/mL)
Drug class: Mast cell stabilizers

Medically reviewed by on Aug 14, 2023. Written by Cerner Multum.

What is cromolyn sodium inhalation?

Cromolyn sodium works by preventing the release of substances in the body that cause inflammation.

Cromolyn sodium inhalation is used to prevent bronchial asthma attacks in adults and children who are at least 2 years old.

Cromolyn sodium inhalation is also used to prevent bronchospasm caused by exercise or exposure to cold dry air, chemicals, or environmental pollutants or allergens (such as animal dander or chemicals used in manufacturing).

Cromolyn sodium inhalation may also be used for purposes not listed in this medication guide.

Cromolyn sodium inhalation side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Cromolyn sodium may cause serious side effects. Call your doctor at once if you have:

Common side effects of cromolyn sodium may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use cromolyn sodium if you are allergic to cromolyn sodium.

To make sure cromolyn sodium inhalation is safe for you, tell your doctor if you have:

Cromolyn sodium inhalation is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

It is not known whether cromolyn sodium inhalation passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Cromolyn sodium inhalation is not approved for use by anyone younger than 2 years old.

How should I use cromolyn sodium inhalation?

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Cromolyn sodium is not a rescue medicine. It will not work fast enough to treat an asthma attack. Use only a fast acting inhalation medicine for an asthma attack. Tell your doctor if it seems like your asthma medications don't work as well.

To use the solution with a nebulizer:

Do not swallow this medicine.

To prevent bronchial asthma attacks, cromolyn sodium inhalation is usually given 4 times daily.

To prevent bronchospasm caused by exercise or environmental factors, use the medicine 10 to 15 minutes before exercise or exposure.

Follow your doctor's dosing instructions very carefully. Your dose needs may change if you have surgery, are ill, are under stress, or have recently had an asthma attack.

It may take several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 4 weeks of using cromolyn sodium.

You should not stop using this medicine suddenly. Stopping suddenly may make your condition worse.

Asthma is usually treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Every person with asthma should remain under the care of a doctor.

If you also use a steroid medication, do not stop using it suddenly or you may have unpleasant withdrawal symptoms. Talk with your doctor about tapering your steroid dose before stopping completely.

Store at room temperature away from moisture, heat, and light. Keep each ampule in the foil pouch until you are ready to use the medicine.

Do not use cromolyn sodium if it has changed colors or has particles in it. Call your pharmacist for new medication.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking cromolyn sodium inhalation?

Do not mix cromolyn sodium inhalation with other medicines in your nebulizer.

Avoid spraying the inhaler into your face or getting the medication in your eyes.

What other drugs will affect cromolyn sodium inhalation?

Other drugs may interact with cromolyn sodium, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.