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cromolyn sodium (inhalation)

Pronunciation

Generic Name: cromolyn sodium (inhalation) (KROE moe lin SOE dee um)
Brand Name:

What is cromolyn sodium inhalation?

Cromolyn sodium works by preventing the release of substances in the body that cause inflammation.

Cromolyn sodium inhalation is used to prevent bronchial asthma attacks in adults and children who are at least 2 years old.

Cromolyn sodium inhalation is also used to prevent bronchospasm caused by exercise or exposure to cold dry air, chemicals, or environmental pollutants or allergens (such as animal dander or chemicals used in manufacturing).

Cromolyn sodium inhalation may also be used for purposes not listed in this medication guide.

What is the most important information I should know about cromolyn sodium inhalation?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What should I discuss with my healthcare provider before using cromolyn sodium inhalation?

You should not use this medicine if you are allergic to cromolyn sodium.

To make sure cromolyn sodium inhalation is safe for you, tell your doctor if you have:

  • heart disease or a heart rhythm disorder;

  • coronary artery disease;

  • kidney disease; or

  • liver disease.

Cromolyn sodium inhalation is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

It is not known whether cromolyn sodium inhalation passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Cromolyn sodium inhalation is not approved for use by anyone younger than 2 years old.

How should I use cromolyn sodium inhalation?

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Cromolyn sodium is not a rescue medicine. It will not work fast enough to treat an asthma attack. Use only a fast acting inhalation medicine for an asthma attack. Tell your doctor if it seems like your asthma medications don't work as well.

To use the solution with a nebulizer:

  • Break open the ampule and empty the medicine into the chamber of the nebulizer. Attach the mouthpiece or face mask, then attach the drug chamber to the compressor.

  • Sit upright in a comfortable position. Place the mouthpiece into your mouth or put on the face mask, covering your nose and mouth. Turn on the compressor.

  • Breathe in slowly and evenly until no more mist is formed by the nebulizer and the drug chamber is empty.

  • Clean the nebulizer after each use. Follow the cleaning directions that came with your nebulizer.

Do not swallow this medicine.

To prevent bronchial asthma attacks, cromolyn sodium inhalation is usually given 4 times daily.

To prevent bronchospasm caused by exercise or environmental factors, use the medicine 10 to 15 minutes before exercise or exposure.

Follow your doctor's dosing instructions very carefully. Your dose needs may change if you have surgery, are ill, are under stress, or have recently had an asthma attack.

It may take several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 4 weeks of using cromolyn sodium.

You should not stop using this medicine suddenly. Stopping suddenly may make your condition worse.

Asthma is usually treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Every person with asthma should remain under the care of a doctor.

If you also use a steroid medication, do not stop using it suddenly or you may have unpleasant withdrawal symptoms. Talk with your doctor about tapering your steroid dose before stopping completely.

Store at room temperature away from moisture, heat, and light. Keep each ampule in the foil pouch until you are ready to use the medicine.

Do not use cromolyn sodium if it has changed colors or has particles in it. Call your pharmacist for new medication.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking cromolyn sodium inhalation?

Do not mix cromolyn sodium inhalation with other medicines in your nebulizer.

Avoid spraying the inhaler into your face or getting the medication in your eyes.

Cromolyn sodium inhalation side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • worsening asthma symptoms; or

  • coughing, wheezing, choking, or other breathing problems after using this medicine.

Common side effects may include:

  • sneezing, stuffy nose;

  • cough; or

  • mild wheezing.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

Cromolyn sodium dosing information

Usual Adult Dose for Asthma -- Maintenance:

Administer 20 mg (1 vial) via nebulizer 4 times a day at regular intervals

Prophylaxis of acute bronchospasm due to exercise, exposure to cold dry air, or environmental allergens: 20 mg (1 vial) via nebulizer shortly before anticipated exposure

Comments:
-This drug is a prophylactic agent to be used in patients whose symptoms are sufficiently frequent to require a continuous regimen of medications; the effect is usually evident after several weeks, although some patients show an almost immediate response.
-This drug should not be added to a therapeutic regimen during an acute episode; therapy should be started once asthma is controlled, the airway is cleared, and the patient is able to inhale adequately.

Use: For the management of bronchial asthma

Usual Adult Dose for Systemic Mastocytosis:

Initial dose: 200 mg (2 ampules) orally one-half hour before meals and at bedtime
-If satisfactory control is not achieved within 2 to 3 weeks, may increase dose.
Maintenance dose: May reduce dose to the minimum required to maintain adequate control once a therapeutic response has been achieved.
Maximum dose: 40 mg/kg/day

Comment:
-Use of this product has been associated with improvement in diarrhea, flushing, headaches, vomiting, urticaria, abdominal pain, nausea, and itching in some patients.

Use: For the management of patients with mastocytosis.

Usual Pediatric Dose for Asthma -- Maintenance:

Age: 2 years or older:

Administer 20 mg (1 vial) via nebulizer 4 times a day at regular intervals

Prophylaxis of acute bronchospasm due to exercise, exposure to cold dry air, or environmental allergens: 20 mg (1 vial) via nebulizer shortly before anticipated exposure

Comments:
-This drug is a prophylactic agent to be used in patients whose symptoms are sufficiently frequent to require a continuous regimen of medications; the effect is usually evident after several weeks, although some patients show an almost immediate response.
-This drug should not be added to a therapeutic regimen during an acute episode; therapy should be started once asthma is controlled, the airway is cleared, and the patient is able to inhale adequately.

Use: For the management of bronchial asthma

Usual Pediatric Dose for Systemic Mastocytosis:

Age: 2 to 12 years old:
Initial dose: 100 mg (1 ampule) orally one-half hour before meals and at bedtime

Age: 13 years or older:
Initial dose: 200 mg (2 ampules) orally one-half hour before meals and at bedtime

-If satisfactory control is not achieved within 2 to 3 weeks, may increase dose to no more than 40 mg/kg/day.
Maintenance dose: Once a therapeutic response has been achieved, the dose may be reduced to the minimum required to maintain adequate control.
Maximum dose: 40 mg/kg/day

Comment:
-Use of this product has been associated with improvement in diarrhea, flushing, headaches, vomiting, urticaria, abdominal pain, nausea, and itching in some patients.
-Not recommended for patients less than 2 years of age unless the potential benefits clearly outweigh the risks.

Use: For the management of patients with mastocytosis.

What other drugs will affect cromolyn sodium inhalation?

Other drugs may interact with cromolyn sodium, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

  • Your pharmacist can provide more information about cromolyn sodium inhalation.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 6.01. Revision Date: 2016-08-23, 11:19:34 AM.

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