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Prilosec and Anxiety: What Users Say

Anxiety: mentioned by 4 users (7.5%)

Based on user experiences from 53 Prilosec reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

anxiety 7.5%
nausea 5.7%
pain 5.7%

Reviews for Prilosec

Commonly mentioned side effects
  • Pre...
  • Taken for less than 1 month
  • September 25, 2019

For GERD "DO NOT TAKE THIS MEDICINE!!!!! This medicine has ripped the life out from inside me. I went from being my totally normal happy self to having serious panic attacks, constant anxiety/depression, and a general feeling of hopelessness. The symptoms started on my 12th day, and I stopped taking the pill on my 13th day. It is a week later, and the panic attacks, anxiety, depression, and hopelessness still remain. This drug is poison to me and many others!!!"

1 / 10
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  • jus...
  • July 24, 2015

For GERD "I have taken Prilosec for over 15 years. It works great for the heartburn/reflux/GERD. But let me tell you what it took away from me! It dropped my iron and my iron stores to the bottom, it also took my B12 to the bottom. It also, after years of taking it, gave me anxiety, cramping of muscles, and led to my potassium being low as well. Then, most recently, I kept having a horrible burning in my stomach, well, guess what Prilosec gave me most of all! A stomach full of gastric polyps!! So now I have weaned myself off this horrible medicine because gastric polyps are a side effect of it and no one tells you! And if you keep taking it, well, guess what, it makes even more in your stomach once it starts!! So I weaned myself off it, took over a month."

7 / 10
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  • Mar...
  • September 6, 2021

For Duodenal Ulcer "DO NOT TAKE HORRIFYING. Took the pills against my better judgment for a nagging ulcer/gastritis per my doc. I usually prefer a holistic route. Mistake. Five days in, an ER trip in an ambulance from sudden dizziness, painful pounding chest, panic like I was dying, extreme sweating, numb hands and feet, and pulse through the roof. Tests showed nothing but ended up back in the ER after night after night of undeniable horrific panic, sweating, extreme anxiety (I have never experienced anxiety or anything panic attack related before in my life), claustrophobic and anxiety-ridden nervous thoughts that are unshakable. No sleep for days. With two toddlers, it was torture. It could not have been anything but these awful pills obviously. I quit the pills, am seeing an acupuncturist and herbs to detox. Better but still a work in progress. Please do NOT risk your mental health over this poison. Not worth it one bit."

1 / 10
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Frequently asked questions

  • yez...
  • Taken for less than 1 month
  • April 19, 2022

For GERD "For starters, I have anxiety, and a lot of reviews said that they had severe anxiety while on this medication, which really worried me. I waited for a while until I was in a positive mindset to take it to avoid quitting the medication over something that wasn't real, like my normal anxiety. Eventually, I started, and by day 2, I started to notice my stomach stopped causing problems. I didn't necessarily feel good, but I stopped feeling bad, which was positive. I got really happy about this as I've been dealing with heartburn for over a year now. However, on day 5, I noticed I started waking up with decently intense anxiety, which was brand new to me. Now, when I say this, I don't want you to think I was full-blown panicking and hospitalized because I was not. I just felt very on edge and was able to push through it fine. But after time, I realized it was enough for me to give up on trying this medicine. All in all, you'll be fine to try it, and if it makes you feel bad, you will definitely know."

1 / 10
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