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Ranitidine Side Effects

Medically reviewed by Drugs.com. Last updated on Mar 27, 2024.

Applies to ranitidine: injection solution.

Serious side effects of ranitidine

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

Other side effects of ranitidine

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

For healthcare professionals

Applies to ranitidine: compounding powder, injectable solution, intravenous solution, oral capsule, oral granule effervescent, oral syrup, oral tablet, oral tablet effervescent.

General adverse events

The most commonly reported side effect for IM administration was injection site pain, and the most commonly reported side effects with IV administration were localized pain and burning.[Ref]

Gastrointestinal

Abdominal pain, constipation, and nausea tended to improve with continued treatment.[Ref]

Cardiovascular

Bradycardia, atrioventricular block, tachycardia, and asystole have occurred in H2 receptor antagonists.[Ref]

Psychiatric

Nervous system

Headache may be related to administration of treatment.[Ref]

Dermatologic

Musculoskeletal

Hepatic

Hepatitis with/without jaundice were usually reversible.

ALT levels increased to at least 2 times the pretreatment levels in patients receiving high IV doses for at least 5 days.[Ref]

Other

Hypersensitivity

Anaphylactic shock occurred after administration of a single dose.[Ref]

Renal

Elevation in serum creatinine was usually slight, and typically normalized with continued treatment.[Ref]

Respiratory

Ocular

Hematologic

Leukopenia, granulocytopenia, and thrombocytopenia were usually reversible.[Ref]

Genitourinary

Endocrine

Metabolic

Local

References

1. (2001) "Product Information. Zantac (ranitidine)." Glaxo Wellcome

2. (2002) "Product Information. Zantac 75 (ranitidine)." Pfizer U.S. Pharmaceuticals

3. Cerner Multum, Inc. "UK Summary of Product Characteristics."

4. Cerner Multum, Inc. "Australian Product Information."

Further information

Ranitidine side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.