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User Reviews for Zithromax

Zithromax has an average rating of 7.0 out of 10 from a total of 127 ratings on Drugs.com. 63% of reviewers reported a positive experience, while 23% reported a negative experience.

Condition Avg. Rating Reviews Compare
Bronchitis  
5.9
39 reviews 290 medications
Sinusitis  
8.3
30 reviews 249 medications
Chlamydia Infection  
7.2
17 reviews 59 medications
Upper Respiratory Tract Infection  
8.6
12 reviews 120 medications
Tonsillitis/Pharyngitis  
8.0
6 reviews 83 medications
Bacterial Infection  
4.0
6 reviews 171 medications
Otitis Media  
6.8
5 reviews 137 medications
Pneumonia  
5.5
3 reviews 188 medications
Skin or Soft Tissue Infection  
7.0
3 reviews 163 medications
Pharyngitis  
2.0
2 reviews 47 medications
Mycobacterium avium-intracellulare, Treatment  
7.0
2 reviews 13 medications
Bacterial Endocarditis Prevention  
9.0
1 reviews 56 medications
Cystic Fibrosis  
9.0
1 reviews 104 medications
Summary of Zithromax reviews 7.0 127 reviews

Reviews may be edited to correct grammar/spelling, or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Zithromax

Lianna · April 2, 2021

For Sinusitis: “I am prone to sinus infections, and usually get them with seasonal changes. Sometimes they come with ear stuffiness, and usually with a fever, sore throat, and migraines. The exhaustion is the worst! With 2 small children, this time around, I had to get back on my feet quickly as there are no sick days. Well ZPACK works within hours, even on the pain of the sinus pressure! This has gotten me back to normal more times in my 34 years than I can count. I am extremely thankful for it because I have very few alternatives, being severely allergic to penicillin.”

10 / 10
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Renee rap · November 19, 2013

For Bronchitis: “The only medicine that works on my bronchitis I've tried others and suffered more. For me it starts working in 2 days. No side effects for me just relief. I love it. But I really need to quit smoking. I wouldn't get it so often, get it at least 2 times a year.”

10 / 10
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Anonymous · January 30, 2012

For Bronchitis: “Zithromax works. I see a lot of websites stating that bronchitis is usually caused by a virus. The fact is, that although the triggering mechanism that brought on the bronchitis may be a virus, a secondary infection of bacteria is common. My entire family had bronchitis for several weeks. Zithromax will get rid of it in most cases. Don't believe the nonsense that you don't need antibiotics- after a couple of weeks of this, go get some Zithromax. It works!”

9 / 10
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ShawnieMichael · Taken for less than 1 month · December 12, 2014

For Bronchitis: “I suffere from asthma and would frequently come down with bronchitis. This Zithromax is a lifesaver. I love how it helps me get over it quickly and I am on my feet again within the week. Best prescription ever.”

10 / 10
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Alcor · Taken for less than 1 month · February 11, 2015

For Bronchitis: “This stuff starts working on Day One. Within a couple hours of taking it, I already feel like the congestion has halted and just needs to clear up. Make sure to take the whole pack, but all three times I've ever had bronchitis sneak in during a cold, Zithromax knocks it right out. No side effects for me.”

10 / 10
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Pauly D. · December 7, 2015

For Sinusitis: “It's a life saver for me. Chronic sinus problem that occurs twice a year. Slight stomach issues after initial dose. Knocks out brain fog. Had the best night sleep in months. Always take with food, and you will have no issues. Made me feel 90% better 24 hours after initial dosage. Use with Flonase to open passages to help get it all. Only thing that works for my sinus problems.”

10 / 10
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Anonymous · Taken for less than 1 month · October 13, 2012

For Sinusitis: “After suffering from a cold for 8 days, I woke up with extreme pressure in my sinuses and couldn't hear due to my ears being clogged. I was prescribed the 3 day Zithromax and after one day felt sooo much better. The pressure went away and I had a slightly runny nose. One the second day I could breathe without using decongestants. I haven't had any side effects, but maybe a slight pang in my stomache when taking (I usually eat something right after taking). I'm usually resistant to going to the dr. but very glad I did this time.”

10 / 10
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Frequently asked questions

Bronchitis sufferer · Taken for less than 1 month · September 14, 2013

For Bronchitis: “Got a regular head cold about a week ago. The cold is better but the cough got much worse - so violent I can't talk. Went to Urgent Care - they gave me Lortab for coughing, a Z-pack & an inhaler. It's been 2 hours and I am already feeling an improvement. This is the second time in 2 years that this happens to me. I only wish that I could prescribe it to myself at the onset next time instead of trying every other medicine!”

10 / 10
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Steph3 · August 6, 2014

For Sinusitis: “Took away my ear infection but gave me. Nausea, vomiting, loss of appetite, heart palpitations, anxiety, shortness of breath, diarrhea, dizziness, etc... So not worth it. I was less sick before starting this medicine.”

1 / 10
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Chronic Sinusitis · Taken for less than 1 month · October 11, 2014

For Sinusitis: “I have had chronic sinusitis for the better part of 10 years now off and on. It really gets bad as spring changes over to summer as well as summer over to fall. I have taken several different antibiotics over the years and the sinusitis keeps coming back stronger the next year. So I just started the 7 day ZPak yesterday for the first time and just took the second days dosage. Much like most of the other reviews on this site, I am experiencing some minor diarrhea as well as flatulence. Which, in my opinion, can be a deadly combination for a new pair of white boxer briefs! I have not noticed any other side effect as of yet but again I am only on the second day. I will tell you that I am feeling much livelier right now and gained motivation”

9 / 10
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old man 79 · February 29, 2016

For Bronchitis: “Used a number of times over the years and always found it to work better than anything. 250mg capsules (6), 2 to begin then 1 per day, 1 hour before, or 2hours after eating. Lots of coughing up phlegm but clears the chest so can breath properly. Keep lots of tissues handy. It ought to be available over the counter, as in some foreign countries.”

10 / 10
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Lucille 60 · Taken for less than 1 month · January 31, 2016

For Sinusitis: “Was told by a doctor who specialized in respiratory infections, because his main patients were miners, that I would suffer with chronic sinus infections the rest of my life and that a z-pak would work but to really wipe it out, I should use ceftin. So if z-pak does not work for anyone try the ceftin. I get z-pak normally because I can tolerate the azithromycin. A little stomach upset on the day after all meds are taken (6th day), but other than that, good results...usually takes 48 hours for me to feel better since I am older and have a weakened immune system, but on that third day, much much better.”

9 / 10
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Spidero · April 7, 2010

For Sinusitis: “I've used Zithromax 6-Paks for years to treat chronic sinus infections. They always work and have virtually no side effects for me. I have noticed that I need to take the treatment twice for a persistent sinus infection. Usually, one treatment does it. Azithromycin is the ONLY antibiotic that does NOT give me terrible side effects such as stomach aches, cramps, headaches, dizziness, "brain fog".”

9 / 10
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Anonymous · September 8, 2011

For Upper Respiratory Tract Infection: “I have been using Zithromax for the past 6 years to fight off my upper respiratory tract infections. I have tried almost everything else in the military medical inventory to win against the URI's I get yearly (every Sept/Oct Time frame) but Zithromax wins hands down every time. Does not matter during which stage of the URI you begin to take the medicine. The first or second night you will start to fight the infection hardcore and you might notice a fever develop as your body fights against the bacteria. After that its smooth sailing so you feel better by the 3rd day and completely cured by the 5th day. It is definitely a wonder drug and worth the extra money.”

10 / 10
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Anonymous · November 19, 2009

For Sinusitis: “I personally believe The Z-Pak should be the #1 Drug Prescribed on the Market if you need to maintain your Health FAST & be yourself again. I seem to be prone to Strep Throat, Severe Sinustitis & Resp. Infections in the Fall & Winter. A couple of years ago I was 'Due to have Surgery in 6 Days' and was told "if I was sick I would have to Postpone it". Well after waiting a month for this Surgery, planning a Home & Dog Sitter & Time off from work 'working it in with everyone else's Schedules, to me it was Imperative I be well enough 4 all to go as planned'. "5 day Z-Pac was prescribed". It is a no nonsense drug and I can not think of a single side effect. I was well enough for surgery to go on as planned. ”

10 / 10
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Nana · Taken for less than 1 month · April 5, 2021

For Bacterial Infection: “Severe anxiety and nervousness, horrible diarrhea, awful stomach ache, intense nausea, freaky nightmare, horrific headache. I only took 2 pills they was 250mg a piece don't recommend what so ever. Now I'm feeling like death wondering when effects will wear off”

1 / 10
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Amberlee M · Taken for less than 1 month · April 29, 2015

For Bronchitis: “I had the most horrible case of a bronchial infection. I was sick for almost a week. I went to the doctor, I was prescribed a 250mg Z-pack. I began to feel better on the second day, which is where I am now. I am beginning to cough up some phlegm that was making my chest feels so very tight.so far I am not experiencing any side effects. I do take it during a midday snack. I have rated it a 10 so far based on my personal experience. I just hope it clears this completely up.”

10 / 10
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More FAQ

Anonymous · November 9, 2009

For Bronchitis: “I'm on the 3rd day of the 5-day treatment (2 pills on day 1 and 1 pill each of the next 4 days) and have had no bad side effects when taking this medication. My bronchitis finally seems to be clearing up and I'm pleased with this medication.”

9 / 10
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grits91919 · April 10, 2008

For Sinusitis: “I have just started taking the z-pack a few days ago and am already starting to feel A LOT better! I have sinusitus, an ear ache that was caused by a middle ear infection and so far, the pains are a lot more tolerant! THANK YOU Z-PACK!!”

10 / 10
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Smoky38 · August 1, 2019

For Bronchitis: “Zithromax is one of the worst medications I have ever taken. This drug gave me acute liver damage with Liver function readings of 560 @ ferritin of 3000, also acute pain had to go to emergency, This is a dangerous drug , I took it for several weeks 3 times a week for prevention of chest infection at dosage 250mg”

1 / 10
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Auld1957 · October 23, 2009

For Bronchitis: “For about 10 days now, I had a VERY bad cough, and severe congestion in my lungs (coughed SO much till I thought I were going to actually break a rib )...went to my local emergency room, where the attending doctor sent me home with a 'Z Pack' (5 day regimen of the Zithromax, PLUS a bottle of GUAIFENSIN cough syrup). I'm now on my third day of these antibiotics and am not, thankfully, coughing as much as I did.”

9 / 10
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Jmnknight · January 20, 2017

For Sinusitis: “I was prescribed a five day round with the Z-pak after developing a severe flu-like upper respiratory infection with stuffed and painful sinuses plus aches, sore throat, diarrhea, muscle pain, nausea, and more. I had a Rituxan infusion, and all of this started the next day (common side effects or adverse events). I have rheumatoid arthritis, and my immunosystem is screwed to begin with and the Rituxan infusions temporarily make it worse. So I picked up a bug; bam! Long story, short ending. The Z-pak began working almost immediately, and two hours after my second pill of 250 mg (first was 500) I don't feel sick. My sinuses are still a bit clogged but that's livable. I'm impressed.”

10 / 10
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Funkmeister · Taken for less than 1 month · September 2, 2019

For Upper Respiratory Tract Infection: “Waited 10 days to go to the doctor thinking I had bronchitis! I wish I would’ve went to the doctor sooner because I was miserable coughing my head off with phlegm, terrible headaches, fatigue, congestion, and sweats. I ended up having and upper respiratory infection and was given a z pack. After day one I felt soooo much better and was ready to go back to work. I am on day 4 and still coughing up infection, hoping that’s ends soon! Also everyday after I take the pill I get some pretty bad abdominal pain and have to run to the bathroom but only lasting about an hour. I would say the stomach ache is definitely worth it!”

9 / 10
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Mollie · Taken for less than 1 month · January 16, 2020

For Bronchitis: “I would be very careful taking this antibiotic if you have heart issues. I have mitral valve prolapse and tachycardia and this antibiotic made it worse after one dose. I asked my doctor 3 times if it was okay to take if you have heart problems and she said yes. I’ve since read that it could cause an arrhythmia issue. Well great I already have that. Thinking about changing doctors now. Definitely will avoid this antibiotic in the future.”

1 / 10
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7020erh · June 4, 2016

For Bronchitis: “The z pak cleared up my bronchitis right away. However it almost instantly caused symptoms of gastritis and pancreatis that made me very ill for five months. I could eat very little but was rapidly losing weight. My doctor found low liver and kidney enzymes and suggested futher tests. A endoscopy, colonoscopy, ultrasound, several lab tests and $1700 later there was no diagnosis but after five months i gradually got better. The next winter I got another cold that turned into bronchitis and was again prescribed a z-pak. Almost immediately the same symptoms occurred and I was just as sick for another 5 months. This time the connection was clear - Z-PAK.”

1 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.