Trimethobenzamide Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Trimethobenzamide	Ondansetron	Promethazine	Enter another drug to compare

Trimethobenzamide

Ondansetron

Promethazine

Prescription only

Prescribed for Nausea/Vomiting. Trimethobenzamide may also be used for purposes not listed in this medication guide.

Prescription only

Ondansetron may be used for the prevention or treatment of nausea and vomiting but it may cause constipation or a headache. Prescribed for Nausea/Vomiting, Gastroenteritis, Nausea/Vomiting -... View more

Prescription only

Promethazine may be used to relieve allergy symptoms and nausea. Sedation is the main side effect and it may interact with several other drugs including antidepressants, antipsychotics, and other... View more

More about Trimethobenzamide

More about Ondansetron

More about Promethazine

Ratings & Reviews

Trimethobenzamide has an average rating of 8.8 out of 10 from a total of 14 ratings on Drugs.com. 85% of reviewers reported a positive effect, while 8% reported a negative effect.

Ondansetron has an average rating of 7.8 out of 10 from a total of 494 ratings on Drugs.com. 73% of reviewers reported a positive effect, while 18% reported a negative effect.

Promethazine has an average rating of 7.3 out of 10 from a total of 389 ratings on Drugs.com. 66% of reviewers reported a positive effect, while 21% reported a negative effect.

View all 14 reviews

View all 494 reviews

View all 389 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Trimethobenzamide side effects

Nausea (24.3%)
Vomiting (15.8%)
Constipation (10.1%)
Headaches (9.9%)
Drowsiness (4.5%)
Dizziness (3.6%)
Tiredness (1.4%)

View all Ondansetron side effects

Drowsiness (23.9%)
Nausea (13.1%)
Vomiting (6.2%)
Tiredness (5.1%)
Anxiety (4.6%)
Dizziness (3.9%)
Insomnia (2.8%)

View all Promethazine side effects

Drug Class

Anticholinergic antiemetics

5HT3 receptor antagonists

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	30 capsule
Strength	300 mg
Per unit^*	$1.45
Cost^*	$43.54

View all Trimethobenzamide prices

Quantity	20 mL
Strength	2 mg/mL
Per unit^*	$0.66
Cost^*	$13.14

View all Ondansetron prices

Quantity	1 tablet
Strength	25 mg
Per unit^*	$9.39
Cost^*	$9.39

View all Promethazine prices

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Dosage Forms

Oral capsule

Injectable solution
Oral solution
Oral tablet
Oral tablet, disintegrating

Injectable solution
Oral syrup
Oral tablet
Rectal suppository

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

N/A

4 hours

16 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category N Not classified

See the full pregnancy warnings document.

Category B No proven risk in humans

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 240 drugs are known to interact with Trimethobenzamide:

5 major drug interactions (13 brand and generic names)
235 moderate drug interactions (1089 brand and generic names)

A total of 356 drugs are known to interact with Ondansetron:

127 major drug interactions (449 brand and generic names)
224 moderate drug interactions (848 brand and generic names)
5 minor drug interactions (13 brand and generic names)

A total of 685 drugs are known to interact with Promethazine:

93 major drug interactions (331 brand and generic names)
578 moderate drug interactions (2335 brand and generic names)
14 minor drug interactions (56 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Alcohol can increase the nervous system side effects of trimethobenzamide such as dizziness... View more

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Ask your doctor before using promethazine together with alcohol. This can cause uncontrollable... View more

Disease Interactions

First Approval Date

July 12, 1974

January 04, 1991

March 29, 1951

WADA Class View classifications

N/A

More Information

Patient Resources

Promethazine uses

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Trimethobenzamide Alternatives Compared

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