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Trimethobenzamide Dosage

Applies to the following strength(s): 100 mg/mL100 mg250 mg300 mg

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Nausea/Vomiting

-Oral: 300 mg orally 3 or 4 times a day
-Injection: 200 mg IM 3 or 4 times a day

Comments: Dosage should be adjusted according to the therapy indication, symptom severity, and patient response.

Use: Treatment of postoperative nausea and vomiting, and nausea associated with gastroenteritis.

Usual Pediatric Dose for Nausea/Vomiting

-Oral: The manufacturer gives no specific dosing instructions; Caution recommended.
-Injection: Contraindicated

Comments: This drug should be avoided in children whose signs and symptoms could represent Reye's syndrome.

Use: Treatment of postoperative nausea and vomiting, and nausea associated with gastroenteritis.

Renal Dose Adjustments

CrCl 70 mL/min/1.73 m2 or less: Dosing modifications such as reducing the total dose at each dosing or increasing the dosing interval should be considered; Caution is recommended.

Liver Dose Adjustments

Data not available

Dose Adjustments

Discontinue treatment at the first sign of skin sensitization and if any of the following occur: blood dyscrasias, blurred vision, coma, convulsions, depression, diarrhea, disorientation, dizziness, drowsiness, headache, jaundice, muscle cramps, and opisthotonos.

Precautions

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration Advice:
-IM administration may cause pain, stinging, burning, redness, and swelling at the injection site; such effects may be minimized by deep injection into the upper outer quadrant of the gluteal region and by avoiding the escape of solution along the route.
-The injectable form is intended for IM administration only; IV use is not recommended.

Storage Requirements:
-This drug should be stored between 20 to 25 degrees Celsius (68 to 77 Fahrenheit) and protected from light.

Patient advice:
-This drug may cause drowsiness; avoid driving and potentially dangerous activities such as operating machinery until you know how this drug affects you.
-Avoid alcohol during treatment.

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