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Trimethobenzamide Dosage

Medically reviewed by Drugs.com. Last updated on Jul 31, 2023.

Applies to the following strengths: 100 mg/mL; 100 mg; 250 mg; 300 mg

Usual Adult Dose for Nausea/Vomiting

Oral: 300 mg orally 3 or 4 times a day
IM Injection: 200 mg IM 3 or 4 times a day

Comment: Dosage should be adjusted according to the therapy indication, symptom severity, and patient response.

Uses:

Renal Dose Adjustments

Renal dysfunction (CrCl 70 mL/min/1.73 m2 or less): Dosing modifications such as reducing the total dose at each dosing or increasing the dosing interval should be considered; Caution is recommended.

Liver Dose Adjustments

Oral Formulations:


IM Injection Formulations: Data not available

Dose Adjustments

Geriatric patients: The daily dosage should be reduced by increasing the dosing interval, then adjust as needed based on therapeutic response and tolerability. Renal function should be monitored.

Discontinue treatment at the first sign of skin sensitization and if any of the following occur: blood dyscrasias, blurred vision, coma, convulsions, depression, diarrhea, disorientation, dizziness, drowsiness, headache, jaundice, muscle cramps, and opisthotonos.

Precautions

Safety and efficacy have not been established in patients younger than 18 years.
This drug is not recommended for use in children.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration Advice:


Storage Requirements:

General:

Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.