Promethazine Interactions
There are 690 drugs known to interact with promethazine, along with 13 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 95 are major, 580 are moderate, and 15 are minor.
- View all 690 medications that may interact with promethazine
- View promethazine alcohol/food interactions (2)
- View promethazine disease interactions (13)
Most frequently checked interactions
View interaction reports for promethazine and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- Ambien (zolpidem)
- Benadryl (diphenhydramine)
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- Flonase (fluticasone nasal)
- Klonopin (clonazepam)
- Lexapro (escitalopram)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- MiraLAX (polyethylene glycol 3350)
- Nexium (esomeprazole)
- Norco (acetaminophen / hydrocodone)
- ProAir HFA (albuterol)
- Protonix (pantoprazole)
- Prozac (fluoxetine)
- Seroquel (quetiapine)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Topamax (topiramate)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D2 (ergocalciferol)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zofran (ondansetron)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Promethazine alcohol/food interactions
There are 2 alcohol/food interactions with promethazine.
Promethazine disease interactions
There are 13 disease interactions with promethazine which include:
- acute alcohol intoxication
- CNS depression
- hematologic toxicity
- hypotension
- liver disease
- antidopaminergic effects 1
- asthma
- anticholinergic effects
- asthma/COPD
- breast cancer
- NMS
- seizure disorders
- antidopaminergic effects 2
Report options
More about promethazine
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- Reviews (395)
- Drug images
- Latest FDA alerts (4)
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: antihistamines
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Benadryl
Benadryl is an antihistamine and is used to treat sneezing, runny nose, itching and other ...
Claritin
Claritin is an antihistamine used to treat the symptoms of allergies, such as sneezing, watery ...
Xolair
Xolair injection (omalizumab) is used to help improve allergic asthma, nasal polyps, and chronic ...
Phenergan
Phenergan (promethazine) is used to treat allergy symptoms and prevent motion sickness. Includes ...
EpiPen
EpiPen (epinephrine) is used for severe allergic reactions (anaphylaxis) to food, drugs, insect ...
Cyproheptadine
Cyproheptadine is used for allergic reactions, allergic rhinitis, allergies, anorexia, anorexia ...
Chlorpheniramine
Chlorpheniramine is used for allergic reactions, allergic rhinitis, allergies, cold symptoms, food ...
Epinephrine
Epinephrine (adrenaline) Injection is used to treat severe allergic reactions (anaphylaxis) to ...
Diphenhydramine
Diphenhydramine is an antihistamine used to treat sneezing, runny nose, itching, hives and other ...
Triamcinolone
Triamcinolone is used to treat allergies, skin conditions, ulcerative colitis, and arthritis. Learn ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
