Promethazine Interactions
There are 689 drugs known to interact with promethazine, along with 13 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 94 are major, 580 are moderate, and 15 are minor.
- View all 689 medications that may interact with promethazine
- View promethazine alcohol/food interactions (2)
- View promethazine disease interactions (13)
Most frequently checked interactions
View interaction reports for promethazine and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- Ambien (zolpidem)
- Benadryl (diphenhydramine)
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- Flonase (fluticasone nasal)
- Klonopin (clonazepam)
- Lasix (furosemide)
- Lexapro (escitalopram)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- MiraLAX (polyethylene glycol 3350)
- Nexium (esomeprazole)
- Norco (acetaminophen / hydrocodone)
- ProAir HFA (albuterol)
- Protonix (pantoprazole)
- Seroquel (quetiapine)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Topamax (topiramate)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D2 (ergocalciferol)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zofran (ondansetron)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Promethazine alcohol/food interactions
There are 2 alcohol/food interactions with promethazine.
Promethazine disease interactions
There are 13 disease interactions with promethazine which include:
- acute alcohol intoxication
- CNS depression
- hematologic toxicity
- hypotension
- liver disease
- antidopaminergic effects 1
- asthma
- anticholinergic effects
- asthma/COPD
- breast cancer
- NMS
- seizure disorders
- antidopaminergic effects 2
Report options
More about promethazine
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- Reviews (389)
- Drug images
- Latest FDA alerts (4)
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: antihistamines
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Loratadine
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Zofran
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Xolair
Xolair injection (omalizumab) is used to help improve allergic asthma, nasal polyps, and chronic ...
Zyrtec
Zyrtec (cetirizine) is used to treat allergy symptoms such as sneezing, itching, watery eyes, or ...
Fentanyl
Fentanyl is an opioid medicine used to treat moderate to severe pain, but it can be misused, abused ...
Diphenhydramine
Diphenhydramine is an antihistamine used to treat sneezing, runny nose, itching, hives and other ...
Montelukast
Montelukast is a daily oral medication used to prevent asthma attacks, exercise-induced ...
Clonazepam
Clonazepam is used to treat seizures and panic disorder. Learn about side effects, interactions and ...
Fluticasone nasal
Fluticasone nasal is used for allergic rhinitis, allergies, chronic rhinosinusitis with nasal ...
Hydroxyzine
Hydroxyzine is an antihistamine used to treat itching, hives, and anxiety. It also acts as a ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
