Promethazine Drug Interactions
A total of 1166 drugs (6333 brand and generic names) are known to interact with promethazine.
- 84 major drug interactions (316 brand and generic names)
- 1028 moderate drug interactions (5715 brand and generic names)
- 54 minor drug interactions (302 brand and generic names)
Common medications checked in combination with promethazine
- Advil (ibuprofen)
- Ambien (zolpidem)
- azithromycin
- Benadryl (diphenhydramine)
- Claritin (loratadine)
- codeine
- cyclobenzaprine
- Cymbalta (duloxetine)
- dextromethorphan
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- hydrocodone
- Klonopin (clonazepam)
- Lexapro (escitalopram)
- Lyrica (pregabalin)
- methadone
- naproxen
- Nexium (esomeprazole)
- Norco (acetaminophen / hydrocodone)
- oxycodone
- prednisone
- ProAir HFA (albuterol)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Topamax (topiramate)
- tramadol
- trazodone
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zofran (ondansetron)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Check for interactions with promethazine
promethazine alcohol/food Interactions
There is 1 alcohol/food interaction with promethazine
promethazine disease Interactions
There are 18 disease interactions with promethazine which include:
- Anticholinergic Effects
- Acute Alcohol Intoxication
- Cardiovascular Disease
- Cns Depression
- Head Injury
- Antidopaminergic Effects 1
- Asthma
- Asthma/Copd
- Breast Cancer
- Dystonic Reactions
- Hematologic Toxicity
- Liver Disease
- Nms
- Parkinsonism
- Renal Dysfunction
- Seizure Disorders
- Tardive Dyskinesia
- Antidopaminergic Effects 2
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No information available. |
Do not stop taking any medications without consulting your healthcare provider.
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