Promethazine Alternatives Compared
| Promethazine | Xolair (omalizumab) | Zyrtec (cetirizine) |
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| Promethazine | Xolair (omalizumab) | Zyrtec (cetirizine) |
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Prescription only
Promethazine may be used to relieve allergy symptoms and nausea. Sedation is the main side effect and it may interact with several other drugs including antidepressants, antipsychotics, and other... View more |
Prescription only
Xolair is an injectable preparation that works by preventing IgE from binding to IgE receptors on mast cells and basophils and may be used to treat allergic asthma, nasal polyps, chronic idiopathic... View more |
Prescription and OTC
Zyrtec is an antihistamine that effectively treats allergic reactions such as hay fever or skin reactions caused by insect bites. Although drowsiness with Zyrtec is uncommon, Zyrtec is more likely... View more |
Related suggestions |
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| More about Promethazine | More about Xolair (omalizumab) | More about Zyrtec (cetirizine) | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Promethazine has an average rating of 7.2 out of 10 from a total of 389 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 21% reported a negative effect. |
Xolair has an average rating of 7.5 out of 10 from a total of 229 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 18% reported a negative effect. |
Zyrtec has an average rating of 5.8 out of 10 from a total of 197 ratings on Drugs.com. 43% of reviewers reported a positive effect, while 36% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||
View all Promethazine side effects |
View all Xolair side effects |
View all Zyrtec side effects |
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| Drug Class | ||||||||||||||||||
| Generic Availability | ||||||||||||||||||
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Lower cost generic |
N/A |
Lower cost generic approved | ||||||||||||||||
| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
View all Promethazine prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Zyrtec prices |
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| Dosage Forms | ||||||||||||||||||
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| Brand Names | ||||||||||||||||||
| Adgan, Anergan 50, Antinaus 50, Phenadoz, Promethegan | Other omalizumab brands include: Omlyclo | Other cetirizine brands include: All Day Allergy, All Day Allergy Children's, Aller-Tec, Aller-Tec Children's, Alleroff, Children's Allergy Relief, Equate Allergy Relief, PediaCare Children's 24-Hour Allergy, Quzyttir, Zyrtec Hives View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||
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16 hours |
624 hours |
10.6 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 688 drugs are known to interact with Promethazine:
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A total of 29 drugs are known to interact with Xolair:
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A total of 254 drugs are known to interact with Zyrtec:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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March 29, 1951 |
June 20, 2003 |
N/A |
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| WADA Class View classifications | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.