Comparing Ondansetron vs Promethazine
| Ondansetron | Promethazine |
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| Ondansetron | Promethazine |
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Prescription only
Ondansetron may be used for the prevention or treatment of nausea and vomiting but it may cause constipation or a headache. Prescribed for Nausea/Vomiting, Nausea/Vomiting - Postoperative... View more |
Prescription only
Promethazine may be used to relieve allergy symptoms and nausea. Sedation is the main side effect. Prescribed for Light Sedation, Allergic Reactions, Allergic Rhinitis, Anaphylaxis, Motion Sickness... View more |
Related suggestions Nausea/Vomiting
Popular comparisons
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| More about Ondansetron | More about Promethazine | ||||||||||||||||
| Generic Status | |||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Ondansetron has an average rating of 7.7 out of 10 from a total of 462 ratings on Drugs.com. 72% of reviewers reported a positive effect, while 19% reported a negative effect. |
Promethazine has an average rating of 7.2 out of 10 from a total of 361 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 21% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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See also: ondansetron side effects in more detail. |
See also: promethazine side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all ondansetron prices |
View all promethazine prices |
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| Dosage Form(s) Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Zofran, Zofran ODT, Zuplenz | Adgan, Anergan 50, Antinaus 50, Phenadoz, Phenergan, Promethegan | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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4 hours |
16 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 330 drugs are known to interact with ondansetron:
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A total of 667 drugs are known to interact with promethazine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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January 04, 1991 |
March 29, 1951 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.