Comparing Ondansetron vs Phenergan
| Ondansetron | Phenergan (promethazine) |
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| Ondansetron | Phenergan (promethazine) |
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Prescription only
Ondansetron may be used for the prevention or treatment of nausea and vomiting but it may cause constipation or a headache. Prescribed for Nausea/Vomiting, Gastroenteritis, Nausea/Vomiting -... View more |
Prescription only
Phenergan may be used to relieve allergy symptoms, nausea, or as a sleeping aid. Sedation is the main side effect. Occasionally, paradoxical reactions (the opposite of what is to be expected) may... View more |
Related suggestions Nausea/Vomiting
Popular comparisons
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| More about Ondansetron | More about Phenergan (promethazine) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Ondansetron has an average rating of 7.8 out of 10 from a total of 497 ratings on Drugs.com. 73% of reviewers reported a positive effect, while 18% reported a negative effect. |
Phenergan has an average rating of 7.4 out of 10 from a total of 151 ratings on Drugs.com. 69% of reviewers reported a positive effect, while 21% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Ondansetron side effects |
View all Phenergan side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Ondansetron prices |
View all Phenergan prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Other promethazine brands include: Adgan, Anergan 50, Antinaus 50, Phenadoz, Promethegan | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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4 hours |
16 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 359 drugs are known to interact with Ondansetron:
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A total of 688 drugs are known to interact with Phenergan:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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January 04, 1991 |
March 29, 1951 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.