Comparing Ondansetron vs Phenergan
| Ondansetron | Phenergan (promethazine) |
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| Ondansetron | Phenergan (promethazine) |
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Prescription only
Ondansetron may be used for the prevention or treatment of nausea and vomiting but it may cause constipation or a headache. Prescribed for Nausea/Vomiting, Gastroenteritis, Alcohol Use Disorder... View more |
Prescription only
Phenergan may be used to relieve allergy symptoms, nausea, or as a sleeping aid. Sedation is the main side effect. Occasionally, paradoxical reactions (the opposite of what is to be expected) may... View more |
Related suggestions Nausea/Vomiting
Popular comparisons
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| More about Ondansetron | More about Phenergan (promethazine) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Ondansetron has an average rating of 7.8 out of 10 from a total of 499 ratings on Drugs.com. 73% of reviewers reported a positive effect, while 18% reported a negative effect. |
Phenergan has an average rating of 7.4 out of 10 from a total of 151 ratings on Drugs.com. 69% of reviewers reported a positive effect, while 21% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Ondansetron side effects |
View all Phenergan side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Ondansetron prices |
View all Phenergan prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Other promethazine brands include: Adgan, Anergan 50, Antinaus 50, Phenadoz, Promethegan | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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4 hours |
16 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 360 drugs are known to interact with Ondansetron:
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A total of 689 drugs are known to interact with Phenergan:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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January 04, 1991 |
March 29, 1951 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.