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Phenergan and Sleepy: What Users Say

Sleepy: mentioned by 10 users (6.6%)

Based on user experiences from 151 Phenergan reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

drowsiness 19.2%
nausea 13.2%
sleepy 6.6%
anxiety 4.6%
hallucinations 4.6%
tiredness 4.6%
vomiting 4.6%
dizziness 4.0%
allergic reaction 2.6%
restless leg syndrome 2.6%

Reviews for Phenergan

Commonly mentioned side effects
  • Anonymous
  • January 24, 2012

For Opiate Adjunct "I am on opiate pain medication for a back injury from a car accident, and the opiates make me nauseated and vomit. My pain doctor put me on 25mg of Promethazine 3 times a day and it works wonders! It will make you a little sleepy, but once you get used to it, that feeling goes away. I've tried Tigan (Trimethobenzamide) which made the nausea worse. I also tried Zofran (Ondansetron) which I hated because it tastes nasty, and that doesn't help when you are nauseated. I would HIGHLY recommend Promethazine for ANYONE who SUFFERS from nausea due to opiates or chronic nausea!"

10 / 10
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  • Kan...
  • Taken for 1 to 6 months
  • April 8, 2018

For Sedation "I have restarted taking 3 months ago, after coming off amitriptyline cold turkey. These are more suited as you can take most cold and flu medication without issues, which was always an issue. The tablets take effect quickly (1.5 hours). I first started on 50 mg per night, now down to 30 mg due to tablets now making me more sleepy during the daytime than before. I would recommend these to any anxiety or insomnia sufferer as they do not have neuro side effects like other sleepers."

6 / 10
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35 Report
  • jal...
  • February 24, 2010

For Motion Sickness "My husband and I have used Dramamine in the past for motion sickness while on our fishing boat. A 50 mg tablet will put us to sleep within 3 hrs after taking the pill. One time I could not drive home, I was falling asleep at the wheel. I went home and could not keep my eyes open. This time during our cruise, we saw a pharmacist on an island stop, and she gave us Phenergan and told us to take 1 15 mins. before going on a fishing charter. The pills worked wonderfully! We were out in really rough waters on a 30 ft. fishing boat for 4 hrs. Did not even get queasy at all! We were not even tired upon our return either. As a matter of fact, my husband said the pill made him hungry, and he ate more. Phenergan is wonderful! Throw away the Dramamine!"

9 / 10
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41 Report

Frequently asked questions

  • Sza...
  • November 28, 2011

For Nausea/Vomiting "I had gallbladder surgery and got narcotics for pain afterwards. No matter what painkiller I got, they made me vomit even at half the dose. Ondansetron (Zofran) helped some but not fully. Once I got my first dose of Phenergan, my nausea was completely gone. It made me very sleepy, but I was very happy about it. This was the best anti-nausea medication that I ever had!"

10 / 10
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38 Report
  • Anonymous
  • June 30, 2010

For Nausea/Vomiting "This drug is truly amazing! Nobody can figure out why I've been so nauseated and vomiting the last 2 years. When I have a really bad episode, I take promethazine and don't throw up or feel nearly as sick. I don't even get the sleepy side effect, it just makes everything better."

10 / 10
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33 Report

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  • Anonymous
  • June 24, 2010

For Vertigo "I have Meniere's. Phenergan seemed to help for about 2 hours, followed by an urge to throw up and a horrible headache. I also had to unscrew the fluorescent bulbs above my desk at work, it just felt like a rollercoaster. I felt better when I was moving, but when I stopped, I was still moving! The ENT switched me to 1 mg Ativan, which worked (finally!), but it made me sleepy until I got used to it."

3 / 10
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29 Report
  • res...
  • September 19, 2008

For Nausea/Vomiting "Phenergan has been a lifesaver. I am a little over 5 months pregnant and have not been able to enjoy a meal for at least the last 3-4 months. I went to the doctor, and she tried me on Phenergan, and it has truly been a blessing. I can eat and not be scared that I'll vomit. It does make me a little sleepy if I take the entire pill, but if I just take half, I can eat at work during the day. At home, I take the whole thing and sleep like a baby. My only negative is there is really no information about how it affects an unborn child. A couple of my friends have taken it, and they have healthy, happy kids. I'll be praying for the same result."

9 / 10
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31 Report
  • wor...
  • Taken for 1 to 6 months
  • September 23, 2024

For Sedation "I have severe anxiety with taking medication, but I was desperate due to my ADHD. I have insomnia and can sit up until 5/6 am. I read the reviews, so I decided half was enough, and it worked like a charm. Yes, the next day you feel groggy and sleepy for a while, same with any sleep medication. It’s weighing up your cons and pros. Works for me, but I only take 1-2 times a week when I REALLY need it. If it’s gone past 1 am, I won’t bother as I know I won’t get up if I take it and will just have it the next day 1-2 hours before bed."

10 / 10
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  • Anonymous
  • April 7, 2009

For Nausea/Vomiting "This drug did make me very sleepy, but it immediately stopped my nausea and vomiting."

10 / 10
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28 Report
  • Ano...
  • Taken for 2 to 5 years
  • October 3, 2021

For Nausea/Vomiting "I take this for severe nausea, 25 mg, but it never made me sleepy."

9 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.