Phenergan Interactions
There are 689 drugs known to interact with Phenergan (promethazine), along with 13 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 94 are major, 580 are moderate, and 15 are minor.
- View all 689 medications that may interact with Phenergan
- View Phenergan alcohol/food interactions (2)
- View Phenergan disease interactions (13)
Most frequently checked interactions
View interaction reports for Phenergan (promethazine) and the medicines listed below.
- Benadryl (diphenhydramine)
- Benadryl (diphenhydramine)
- Cymbalta (duloxetine)
- Cymbalta (duloxetine)
- Flexeril (cyclobenzaprine)
- Flexeril (cyclobenzaprine)
- gabapentin
- gabapentin
- Klonopin (clonazepam)
- Klonopin (clonazepam)
- lisinopril
- lisinopril
- Norco (acetaminophen / hydrocodone)
- Norco (acetaminophen / hydrocodone)
- omeprazole
- omeprazole
- oxycodone
- oxycodone
- prednisone
- prednisone
- tramadol
- tramadol
- trazodone
- trazodone
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Xanax (alprazolam)
- Zofran (ondansetron)
- Zofran (ondansetron)
Phenergan alcohol/food interactions
There are 2 alcohol/food interactions with Phenergan (promethazine).
Phenergan disease interactions
There are 13 disease interactions with Phenergan (promethazine) which include:
- acute alcohol intoxication
- CNS depression
- hematologic toxicity
- hypotension
- liver disease
- antidopaminergic effects 1
- asthma
- anticholinergic effects
- asthma/COPD
- breast cancer
- NMS
- seizure disorders
- antidopaminergic effects 2
Report options
More about Phenergan (promethazine)
- Phenergan consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (151)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Generic availability
- Support group
- Drug class: antihistamines
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Zofran
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Loratadine
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Meclizine
Meclizine is used to treat or prevent nausea, vomiting, and dizziness caused by motion sickness ...
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Cetirizine treats cold or allergy symptoms such as sneezing, itching, watery eyes, or runny nose ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
