Protonix Alternatives Compared
| Protonix | Omeprazole | Pantoprazole |
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| Protonix (pantoprazole) | Omeprazole | Pantoprazole |
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Prescription only
Protonix is used for the treatment of conditions associated with excessive acid production in the esophagus and stomach. Long-term use may be associated with magnesium and vitamin B12 deficiency and... View more |
Prescription and OTC
Omeprazole decreases stomach acid production which promotes the healing of gastric and duodenal ulcers and other inflamed areas of gastrointestinal tissue. The risk of interactions with omeprazole... View more |
Prescription only
Pantoprazole is a proton pump inhibitor that decreases acid secretion in the stomach and may be given to relieve the symptoms of heartburn or to allow inflamed tissue in the gastrointestinal tract to... View more |
Related suggestions Helicobacter Pylori Infection
Stomach Ulcer (Gastric Ulcer)
Erosive Esophagitis
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| More about Protonix (pantoprazole) | More about Omeprazole | More about Pantoprazole | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Protonix has an average rating of 7.2 out of 10 from a total of 81 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 23% reported a negative effect. |
Omeprazole has an average rating of 4.5 out of 10 from a total of 482 ratings on Drugs.com. 31% of reviewers reported a positive effect, while 54% reported a negative effect. |
Pantoprazole has an average rating of 4.9 out of 10 from a total of 422 ratings on Drugs.com. 35% of reviewers reported a positive effect, while 48% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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See also: Protonix side effects in more detail. |
See also: omeprazole side effects in more detail. |
See also: pantoprazole side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Protonix prices and generic prices |
View all omeprazole prices |
View all pantoprazole prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Other pantoprazole brands include: Protonix IV | Omesec, Prilosec, Prilosec OTC | Protonix, Protonix IV | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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1 hour |
1.5 hours |
1 hour |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 163 drugs are known to interact with Protonix:
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A total of 220 drugs are known to interact with omeprazole:
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A total of 163 drugs are known to interact with pantoprazole:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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February 02, 2000 |
June 20, 2003 |
February 02, 2000 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient resources | ||||||||||||||||||||||||||
| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.