Comparing Pepcid vs Protonix
| Pepcid (famotidine) | Protonix (pantoprazole) |
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| Pepcid (famotidine) | Protonix (pantoprazole) |
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Prescription only
Prescribed for Erosive Esophagitis, Duodenal Ulcer, GERD, Duodenal Ulcer Prophylaxis, Indigestion, Pathological Hypersecretory Conditions, Peptic Ulcer, Stomach Ulcer, Upper GI Hemorrhage... View more |
Prescription only
Protonix is used to treat erosive esophagitis associated with gastroesophageal reflux disease (GERD), hypersecretory conditions including Zollinger-Ellison (ZE) syndrome, and for the maintenance of... View more |
Related suggestions Stomach Ulcer
Erosive Esophagitis
Duodenal Ulcer
Popular comparisons
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| More about Pepcid (famotidine) | More about Protonix (pantoprazole) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Pepcid has an average rating of 6.0 out of 10 from a total of 10 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 30% reported a negative effect. |
Protonix has an average rating of 7.2 out of 10 from a total of 83 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 22% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Pepcid side effects |
View all Protonix side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Lower cost generic approved | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Pepcid prices |
View all Protonix prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other famotidine brands include: Acid Control, Acid Controller Maximum Strength, Acid Controller Original Strength, Acid Reducer Maximum Strength, Acid Reducer Original Strength, Acid Reducer-Famotidine, Heartburn Relief, Heartburn Relief Maximum Strength, Pepcid AC, Pepcid AC Chewable Tablets, Pepcid AC Maximum Strength, Pepcid AC Maximum Strength Tablets, Pepcid Oral Suspension, Zantac 360 View more | Other pantoprazole brands include: Protonix IV | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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4 hours |
1 hour |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 313 drugs are known to interact with Pepcid:
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A total of 181 drugs are known to interact with Protonix:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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October 15, 1986 |
February 02, 2000 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
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N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.