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Protonix and Swelling: What Users Say

Swelling: mentioned by 4 users (4.8%)

Based on user experiences from 83 Protonix reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

headaches 12.0%
nausea 8.4%
heartburn 6.0%
dizziness 4.8%
swelling 4.8%
anxiety 3.6%
diarrhea 3.6%
gas 3.6%
stomach pain 3.6%
vomiting 3.6%

Reviews for Protonix

Commonly mentioned side effects
  • Anonymous
  • Taken for 1 to 6 months
  • June 21, 2012

For GERD "This was not effective in reducing acid. Four days after stopping Nexium and starting Protonix the heartburn started and I had to take Gaviscon. I had a 3-month supply, so I kept taking it and ended up with a swollen, painful esophagus and difficulty swallowing with vomiting. I stopped taking Nexium because my insurance no longer would cover it."

1 / 10
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98 Report
  • Wag...
  • Taken for less than 1 month
  • October 6, 2016

For GERD "I have had severe GERD/acid reflux for nearly 6 years. It has put me in the hospital 7 times now and has totally destroyed my teeth, which I have always been meticulous about caring for. Presently, it's also causing me swallowing problems and voice troubles. The pain the GERD can generate is an actual true '10'-far, far worse than the pain I experienced from a quad cardiac bypass surgery. My doctor gave me Protonix for it, and it worked very well on reducing, perhaps, 80% of the pain. Unfortunately, the medication caused peripheral edema big time, and I had to go off of it again. The edema immediately went away, but the pain came back too. I have noticed this reaction from almost all proton pumps that I have tried to date."

5 / 10
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40 Report
  • Anonymous
  • October 17, 2011

For Stomach Ulcer "Took the burn away in my stomach, but made my hands and fingers swell."

1 / 10
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41 Report

Frequently asked questions

  • GMc...
  • Taken for less than 1 month
  • December 8, 2021

For Duodenal Ulcer "This medication helped my reflux and my stomach pain, but after 3 weeks, my extremities started swelling. Will call my physician for a different med."

4 / 10
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8 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.