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Protonix and Nausea: What Users Say

Nausea: mentioned by 7 users (8.4%)

Based on user experiences from 83 Protonix reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

headaches 12.0%
nausea 8.4%
heartburn 6.0%
dizziness 4.8%
swelling 4.8%
anxiety 3.6%
diarrhea 3.6%
gas 3.6%
stomach pain 3.6%
vomiting 3.6%

Reviews for Protonix

Commonly mentioned side effects
  • Jen...
  • Taken for 6 months to 1 year
  • October 7, 2018

For GERD "I have both IBS and Gastritis. Protonix has been a complete game changer for me. Without it, I have chronic nausea, difficulties tolerating food, vomiting, low energy, and headache. My days were very difficult prior to being prescribed this med. I feel incredibly better."

10 / 10
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  • Tee...
  • December 17, 2015

For GERD "This was the worst medication I have ever taken. I was just prescribed this medication last week. After being on it for only 2 days, I stopped. Headache was unbearable. I thought I was going to have to go to the hospital to get a CAT scan until I realized it was probably the Protonix. Then there was the nausea that came along as well. Five days later, I'm still nauseous, but used ginger to help with that. Overall, I will never use this medicine again."

1 / 10
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115 Report
  • Anonymous
  • April 15, 2009

For GERD "I had the worst side effects with Protonix. I took it for 15 days and experienced increased anxiety and heart palpitations. I also had dizziness, nausea, and insomnia. Going off of it took 6 days to feel somewhat normal."

1 / 10
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119 Report

See also:

Frequently asked questions

  • Hll...
  • Taken for less than 1 month
  • November 11, 2021

For GERD "I started taking Protonix a few months ago. I’m 19 and have never had any prior health issues besides bad acid reflux. I was taking Protonix for about a week and started to notice awful headaches. By week two, I was having awful dizzy spells, and I avoided going to class because I thought I was going to pass out. I thought all of these side effects were related to when I had COVID a month prior, so I overlooked it. After taking this medicine for a month, I went to the ER twice because I felt like my heart was skipping beats, I was nauseous, couldn’t catch my breath, tingling in my hands and feet, and my dizzy spells were unbearable. The doctors summed it up to panic attacks, which I knew was wrong because I’m not an anxious person. I researched Protonix online and realized a lot of other people had the same side effects. DO NOT take this medicine!!! It made me feel like I was going crazy, and for a whole month, I couldn’t do anything because of dizzy spells!"

1 / 10
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26 Report
  • Mim...
  • Taken for less than 1 month
  • March 5, 2022

For Stomach Ulcer "Prescribed this for a stomach ulcer with possible bleeding. This medication has been a miracle for me since the first dose. Immediately eliminated abdominal pain from the ulcer, and although I am still not able to eat much, I am able to eat solid foods again. This medication did have side effects and made me nauseous, but this stopped after the first three doses, which was also helped with Zofran. However, the side effects were minimal compared to the pain and weakness I was feeling before being prescribed this medication. I go for an endoscopy in a few days, and I’m very hopeful that it has helped to heal the ulcer (not fully, of course, as I haven’t finished the medication yet). I hope this review helps someone!"

10 / 10
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18 Report

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  • Ren...
  • Taken for less than 1 month
  • September 28, 2021

For GERD "Prescribed Protonix by my doctor, and after a week and a half, I had to stop. Almost immediately, anything I ate gave me heartburn (I didn't have frequent heartburn before), headaches every morning, extreme nausea, so much that I had no appetite, foggy brain, joint pain in my hands/wrists, abdominal pain, and depression/anxiety. I wish I would have done my research and asked more questions. I'm on day 2 after stopping, and I feel slightly better. I'm going to try a cleaned-up diet and not eating so late. Let us hope it works."

1 / 10
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  • jim...
  • May 9, 2009

For GERD "I took this drug at bedtime for GERD. Sick to my stomach all night long. Stopped taking it for one night and wasn't sick at all."

1 / 10
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42 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.