Perampanel Alternatives Compared
| Perampanel | Topiramate | Keppra (levetiracetam) |
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| Perampanel | Topiramate | Keppra (levetiracetam) |
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Prescription only
Prescribed for Epilepsy, Seizures. Perampanel may also be used for purposes not listed in this medication guide. |
Prescription only
Topiramate may be prescribed either alone or in combination with other medications for the treatment of certain types of epilepsy, or it may be given for the prevention of migraines. Drowsiness is a... View more |
Prescription only
Keppra is an anticonvulsant that is used in conjunction with other medications for the treatment of certain types of seizures. It may cause drowsiness but it is less likely than some other... View more |
Related suggestions |
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| More about Perampanel | More about Topiramate | More about Keppra (levetiracetam) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Perampanel has an average rating of 5.9 out of 10 from a total of 73 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 38% reported a negative effect. |
Topiramate has an average rating of 6.3 out of 10 from a total of 1337 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 28% reported a negative effect. |
Keppra has an average rating of 5.7 out of 10 from a total of 309 ratings on Drugs.com. 43% of reviewers reported a positive effect, while 34% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Perampanel side effects |
View all Topiramate side effects |
View all Keppra side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Perampanel prices |
View all Topiramate prices |
View all Keppra prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Fycompa | Eprontia, Qudexy XR, Topamax, Trokendi XR | Other levetiracetam brands include: Elepsia XR, Keppra XR, Roweepra, Roweepra XR, Spritam | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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105 hours |
56 hours |
8 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 332 drugs are known to interact with Perampanel:
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A total of 291 drugs are known to interact with Topiramate:
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A total of 239 drugs are known to interact with Keppra:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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October 22, 2012 |
December 24, 1996 |
November 30, 1999 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.