Penicillin v potassium Alternatives Compared

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Penicillin v potassium	Amoxicillin	Doxycycline	Enter another drug to compare

Penicillin v potassium

Amoxicillin

Doxycycline

Prescription only

Prescribed for Bacterial Infection, Fusospirochetosis - Trench Mouth, Clostridioides difficile Infection, Cutaneous Bacillus anthracis, Lyme Disease - Erythema Chronicum Migrans, Middle Ear... View more

Prescription only

Amoxicillin is a penicillin-type antibiotic that may be used to treat infections caused by susceptible bacteria. It is usually well tolerated, but a rash is a common side effect. Prescribed for... View more

Prescription only

Doxycycline is an effective antibiotic that treats a wide range of infections. However, it is not usually recommended for children aged less than eight or pregnant women in the last half of their... View more

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Ratings & Reviews

Penicillin v potassium has an average rating of 6.5 out of 10 from a total of 56 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 27% reported a negative effect.

Amoxicillin has an average rating of 6.4 out of 10 from a total of 367 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 29% reported a negative effect.

Doxycycline has an average rating of 6.4 out of 10 from a total of 1642 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 27% reported a negative effect.

View all 56 reviews

View all 367 reviews

View all 1642 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Nausea (12.5%)
Chills (10.7%)
Headaches (10.7%)
Pain (8.9%)
Anxiety (7.1%)
Upset stomach (7.1%)
Depression (5.4%)

View all Penicillin v potassium side effects

Diarrhea (13.4%)
Nausea (7.9%)
Pain (7.4%)
Headaches (6.8%)
Tiredness (6.0%)
Upset stomach (5.2%)
Yeast infection (4.4%)

View all Amoxicillin side effects

Nausea (19.9%)
Headaches (9.6%)
Acne (7.9%)
Vomiting (7.7%)
Upset stomach (5.4%)
Diarrhea (3.2%)
Dizziness (3.2%)

View all Doxycycline side effects

Drug Class

Natural penicillins

Aminopenicillins

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	6 tablet
Strength	500 mg
Per unit^*	$1.88
Cost^*	$11.26

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Quantity	4 capsule
Strength	500 mg
Per unit^*	$2.61
Cost^*	$10.42

View all Amoxicillin prices

Quantity	2 tablet
Strength	hyclate 100 mg
Per unit^*	$6.62
Cost^*	$13.23

View all Doxycycline prices

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Dosage Forms

Oral powder for reconstitution
Oral tablet

Oral capsule
Oral powder for reconstitution
Oral tablet
Oral tablet, chewable
Oral tablet, extended release

Injectable powder for injection
Oral capsule
Oral delayed release capsule
Oral delayed release tablet
Oral powder for reconstitution
Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

1 hour

1.7 hours

23 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category B No proven risk in humans

See the full pregnancy warnings document.

Category B No proven risk in humans

See the full pregnancy warnings document.

Category D Positive evidence of risk

See the full pregnancy warnings document.

Drug Interactions

A total of 63 drugs are known to interact with Penicillin v potassium:

7 major drug interactions (25 brand and generic names)
50 moderate drug interactions (273 brand and generic names)
6 minor drug interactions (33 brand and generic names)

A total of 64 drugs are known to interact with Amoxicillin:

7 major drug interactions (25 brand and generic names)
50 moderate drug interactions (273 brand and generic names)
7 minor drug interactions (35 brand and generic names)

A total of 237 drugs are known to interact with Doxycycline:

22 major drug interactions (60 brand and generic names)
210 moderate drug interactions (2251 brand and generic names)
5 minor drug interactions (21 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease Interactions

First Approval Date

January 13, 1958

January 18, 1974

December 05, 1967

WADA Class View classifications

N/A

More Information

Patient Resources

Penicillin v potassium uses

Amoxicillin uses

Doxycycline uses

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Penicillin v potassium Alternatives Compared

See also:

Augmentin

Cefdinir

Botox

Clindamycin

Levofloxacin

Metronidazole

Ceftriaxone

Ciprofloxacin

Cephalexin

Azithromycin

Further information

Penicillin v potassium Alternatives Compared

See also:

Further information

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