Nifedipine Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Nifedipine	Topiramate	Aimovig (erenumab)	Enter another drug to compare

Nifedipine

Topiramate

Aimovig (erenumab)

Prescription only

Nifedipine is used in the treatment of vasospastic angina and occasionally for chronic unstable angina as an add-on to other treatments. It should not be used to rapidly drop blood pressure as this... View more

Prescription only

Topiramate may be prescribed either alone or in combination with other medications for the treatment of certain types of epilepsy, or it may be given for the prevention of migraines. Drowsiness is a... View more

Prescription only

Aimovig is used to prevent migraines in adults and is self-administered as a subcutaneous injection once a month. Injection site reactions (pain, redness, or swelling) and constipation are the most... View more

More about Nifedipine

More about Topiramate

More about Aimovig (erenumab)

Ratings & Reviews

Nifedipine has an average rating of 5.0 out of 10 from a total of 165 ratings on Drugs.com. 34% of reviewers reported a positive effect, while 43% reported a negative effect.

Topiramate has an average rating of 6.3 out of 10 from a total of 1343 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 27% reported a negative effect.

Aimovig has an average rating of 5.2 out of 10 from a total of 651 ratings on Drugs.com. 38% of reviewers reported a positive effect, while 43% reported a negative effect.

View all 165 reviews

View all 1343 reviews

View all 651 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Headaches (24.2%)
Swelling (15.2%)
Dizziness (13.9%)
Increased heart rate (10.3%)
Heart palpitations (9.1%)
Insomnia (9.1%)
Shortness of breath (8.5%)

View all Nifedipine side effects

Tingling (15.6%)
Memory loss (12.7%)
Weight loss (11.5%)
Brain fog (10.1%)
Loss of appetite (7.8%)
Depression (6.6%)
Dizziness (6.3%)

View all Topiramate side effects

Constipation (32.3%)
Fatigue (13.7%)
Dizziness (11.1%)
Nausea (10.8%)
Headaches (9.5%)
Bloating (7.4%)
Hair loss (6.9%)

View all Aimovig side effects

Drug Class

Calcium channel blockers

Carbonic anhydrase inhibitor anticonvulsants

CGRP inhibitors

Generic Availability

Lower cost generic

N/A

Pricing and Coupons * Prices are without insurance

We could not find an exact match for this medicine. Try searching the Price Guide directly.

Quantity	7 tablet
Strength	100 mg
Per unit^*	$0.75
Cost^*	$5.22

View all Topiramate prices

We could not find an exact match for this medicine. Try searching the Price Guide directly.

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Dosage Forms

Oral capsule
Oral tablet, extended release

Oral capsule
Oral capsule, extended release
Oral solution
Oral tablet

Subcutaneous solution

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

5 hours

56 hours

672 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Category D Positive evidence of risk

See the full pregnancy warnings document.

Summary unavailable.

See the full pregnancy warnings document.

Drug Interactions

A total of 633 drugs are known to interact with Nifedipine:

27 major drug interactions (107 brand and generic names)
552 moderate drug interactions (3250 brand and generic names)
54 minor drug interactions (259 brand and generic names)

A total of 291 drugs are known to interact with Topiramate:

108 major drug interactions (659 brand and generic names)
180 moderate drug interactions (723 brand and generic names)
3 minor drug interactions (13 brand and generic names)

A total of 3 drugs are known to interact with Aimovig:

3 moderate drug interactions (6 brand and generic names)

Alcohol/Food/Lifestyle Interactions

You should avoid or limit the consumption of grapefruit and grapefruit juice if you are receiving... View more
NIFEdipine and alcohol may have additive effects in lowering your blood pressure. You may... View more

Ask your doctor before using alcohol together with topiramate. This can cause excessive sleep... View more

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease Interactions

First Approval Date

December 31, 1981

December 24, 1996

May 17, 2018

WADA Class View classifications

N/A

More Information

Patient Resources

Nifedipine uses

Topiramate uses

Aimovig uses

Professional Resources

Prescribing information

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Nifedipine Alternatives Compared

See also:

Lasix

Valsartan

Aimovig

Hydrochlorothiazide

Atenolol

Furosemide

Metoprolol

Losartan

Lisinopril

Amlodipine

Further information

Nifedipine Alternatives Compared

See also:

Further information

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