Comparing Methotrexate vs Motrin
Methotrexate | Motrin (ibuprofen) |
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Methotrexate | Motrin (ibuprofen) |
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Prescription only
Methotrexate may be considered for the treatment of psoriasis, rheumatoid arthritis, polyarticular juvenile idiopathic arthritis (pJIA), mycosis fungoides, and certain cancers, such as ALL or... View more |
Prescription and OTC
Prescribed for Back Pain, Chronic Myofascial Pain, Aseptic Necrosis, Pain, Headache, Gout - Acute, Fever, Juvenile Rheumatoid Arthritis, Costochondritis, Diffuse Idiopathic Skeletal Hyperostosis... View more |
Related suggestions |
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More about Methotrexate | More about (ibuprofen) | ||||||||
Ratings & Reviews | |||||||||
Methotrexate has an average rating of 6.5 out of 10 from a total of 337 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 24% reported a negative effect. |
Motrin has an average rating of 8.1 out of 10 from a total of 16 ratings on Drugs.com. 69% of reviewers reported a positive effect, while 13% reported a negative effect. |
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Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Methotrexate side effects |
View all Motrin side effects |
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Drug Class | |||||||||
Generic Availability | |||||||||
Lower cost generic |
Lower cost generic approved | ||||||||
Pricing and Coupons * Prices are without insurance | |||||||||
View all Methotrexate prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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Dosage Forms | |||||||||
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N/A |
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Brand Names | |||||||||
Jylamvo, Methotrexate LPF Sodium, Otrexup, Rasuvo, Trexall, Xatmep | Other ibuprofen brands include: A-G Profen, Actiprofen, Addaprin, Advil, Advil Children's, Advil Film-Coated, Advil Infant's Concentrated Drops, Advil Junior Strength, Advil Liqui-Gels, Advil Migraine, Caldolor, Cap-Profen, Children's ElixSure IB, Children's Motrin, Childrens Ibuprofen Berry, Genpril, Help I Have An Aching Body, IBU-200, Midol IB, Midol Maximum Strength Cramp Formula, Motrin Childrens, Motrin IB, Motrin Infant Drops, Motrin Junior Strength, Motrin Migraine Pain, Motrin Pediatric, NeoProfen, Nuprin, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Proprinal View more | ||||||||
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
15 hours |
4 hours |
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CSA Schedule 1 View glossary of CSA terms | |||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
Prior To 30 Weeks Gestation
Category D
Positive evidence of risk
Starting At 30 Weeks Gestation See the full pregnancy warnings document. |
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Drug Interactions | |||||||||
A total of 726 drugs are known to interact with Methotrexate:
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A total of 416 drugs are known to interact with Motrin:
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Alcohol/Food/Lifestyle Interactions | |||||||||
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Disease Interactions | |||||||||
First Approval Date | |||||||||
December 07, 1953 |
N/A |
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WADA Class View classifications | |||||||||
N/A |
N/A |
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More Information | |||||||||
Patient Resources | |||||||||
N/A |
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Professional Resources | |||||||||
Related Treatment Guide | |||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
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