Comparing Gabapentin vs Topiramate

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Gabapentin Remove Gabapentin from your drug comparison	Topiramate Remove Topiramate from your drug comparison	Add another drug to compare

Gabapentin

Topiramate

Gabapentin may be used in the treatment of partial-onset seizures and nerve pain but is likely to cause dizziness or drowsiness. Gabapentin enacarbil (brand name Horizant), a prodrug of gabapentin... View more

Topiramate may be prescribed either alone or in combination with other medications for the treatment of certain types of epilepsy, or it may be given for the prevention of migraines. Drowsiness is a... View more

Prescription only

Ratings & Reviews

View all 2150 reviews

View all 1138 reviews

Drug Class

Gamma-aminobutyric acid analogs

Carbonic anhydrase inhibitor anticonvulsants

Side Effects

Commonly reported side effects include: ataxia, dizziness, drowsiness, fatigue, fever, nystagmus disorder, sedated state, and viral infection.

See the full gabapentin side effects document.

Commonly reported side effects include: anxiety, ataxia, confusion, diarrhea, diplopia, dizziness, drowsiness, dysphasia, fatigue, lack of concentration, memory impairment, nausea, nervousness, paresthesia, psychomotor disturbance, speech disturbance, depression, visual disturbance, weight loss, dysgeusia, mood changes, and anorexia.

See the full topiramate side effects document.

Pricing and Coupons

* Prices are without insurance

Quantity	100 each
Dosage	300 mg
Per Unit^*	$0.22
Cost^*	$22.42

View all gabapentin prices

Quantity	7 tablet
Dosage	100 mg
Per Unit^*	$2.31
Cost^*	$16.18

View all topiramate prices

Get free Discount Card

Generic Availability

Yes (this medicine)

Dosage Form(s) Available

Oral capsule
Oral solution
Oral tablet

Oral capsule
Oral capsule, extended release
Oral tablet

Brand Names

Fanatrex, Gabarone, Gralise, Neurontin Qudexy XR, Topamax, Trokendi XR

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

6 hours

56 hours

CSA Schedule**

View glossary of terms.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

Category D Positive evidence of risk

See the full Pregnancy Warnings document.

FDA Alerts

FDA Alerts (4)

FDA Alerts (3)

Drug Interactions

A total of 223 drugs are known to interact with gabapentin:

26 major drug interactions (142 brand and generic names)
187 moderate drug interactions (813 brand and generic names)
10 minor drug interactions (52 brand and generic names)

A total of 264 drugs are known to interact with topiramate:

96 major drug interactions (557 brand and generic names)
165 moderate drug interactions (636 brand and generic names)
3 minor drug interactions (12 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Alcohol can increase the nervous system side effects of gabapentin such as dizziness, drowsiness,... View more

Ask your doctor before using alcohol together with topiramate. This can cause excessive sleep,... View more

Disease Interactions

First Approval Date

December 30, 1993

December 24, 1996

WADA Class

View World Anti-Doping Agency classifications.

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer