Comparing Diclofenac vs Excedrin
| Diclofenac | Excedrin (acetaminophen / aspirin / caffeine) |
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| Diclofenac | Excedrin (acetaminophen / aspirin / caffeine) |
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Prescription only
Diclofenac is an effective medicine for relieving pain but may be associated with an increased risk of cardiovascular and gastrointestinal side effects compared with some other NSAIDs. Prescribed... View more |
Over-the-counter
Prescribed for Osteoarthritis, Migraine, Pain/Fever. Excedrin may also be used for purposes not listed in this medication guide. |
Related suggestions Migraine
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| More about Diclofenac | More about Excedrin (acetaminophen / aspirin / caffeine) | ||||||||
| Ratings & Reviews | |||||||||
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Diclofenac has an average rating of 7.3 out of 10 from a total of 695 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 21% reported a negative effect. |
Excedrin has an average rating of 6.8 out of 10 from a total of 39 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 33% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Diclofenac side effects |
View all Excedrin side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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Lower cost generic |
N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||
View all Diclofenac prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Cambia, Cataflam, Lofena, Voltaren, Xiclo, Zipsor, Zorvolex | Other acetaminophen / aspirin / caffeine brands include: Anacin Advanced Headache Formula, Arthriten, Arthriten Inflammatory Pain Formula, Backaid Inflammatory Pain Formula, Bayer Migraine Formula, ConRx Pain Reliever, CVS Extra Strength Headache Relief, Excedrin Extra Strength, Excedrin Migraine, Extra Pain Relief, Genace, Goody's Extra Strength, Goody's Extra-Strength Headache Powders, Goody's Headache Powders, Medique Pain-Off, Migraine Formula, Migraine Relief, PainAid Extra-Strength Formula, Pamprin Max Menstrual Pain Relief, Vanquish View more | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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1.8 hours |
10 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category N
Not classified
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 444 drugs are known to interact with Diclofenac:
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A total of 578 drugs are known to interact with Excedrin:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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July 28, 1988 |
N/A |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
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N/A |
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| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.