Celecoxib Alternatives Compared
| Celecoxib | Cimzia | Methotrexate |
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| Celecoxib | Cimzia (certolizumab) | Methotrexate |
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Prescription only
Celecoxib is a COX-2-specific NSAID that has a lower propensity for gastrointestinal side effects than many other NSAIDs; however, it still may increase the risk of serious cardiovascular thrombotic... View more |
Prescription only
Prescribed for Ankylosing Spondylitis, Crohn's Disease, Crohn's Disease - Active, Crohn's Disease - Maintenance, Non-Radiographic Axial Spondyloarthritis, Plaque Psoriasis, Psoriasis, Psoriatic... View more |
Prescription only
Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers. Side effects can be severe and... View more |
Related suggestions Rheumatoid Arthritis
Popular comparisons
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| More about Celecoxib | More about Cimzia (certolizumab) | More about Methotrexate | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Celecoxib has an average rating of 7.1 out of 10 from a total of 274 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 21% reported a negative effect. |
Cimzia has an average rating of 6.7 out of 10 from a total of 90 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 21% reported a negative effect. |
Methotrexate has an average rating of 6.6 out of 10 from a total of 334 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 23% reported a negative effect. |
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| Drug Class | ||||||||||||||||||
| Side Effects | ||||||||||||||||||
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See also: celecoxib side effects in more detail. |
See also: Cimzia side effects in more detail. |
See also: methotrexate side effects in more detail. |
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| Generic Availability | ||||||||||||||||||
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Lower cost generic |
N/A |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
View all celecoxib prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all methotrexate prices |
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| Dosage Forms Available | ||||||||||||||||||
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| Brand Names | ||||||||||||||||||
| Celebrex, Elyxyb |
N/A |
Jylamvo, Methotrexate LPF Sodium, Otrexup, Rasuvo, Trexall, Xatmep | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
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11 hours |
336 hours |
15 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category C
Risk cannot be ruled out
Prior To 30 Weeks Gestation
Category D
Positive evidence of risk
Starting At 30 Weeks Gestation See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 422 drugs are known to interact with celecoxib:
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A total of 427 drugs are known to interact with Cimzia:
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A total of 695 drugs are known to interact with methotrexate:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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December 31, 1998 |
N/A |
December 07, 1953 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
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| Professional Resources | ||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.