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Celecoxib and Headaches: What Users Say

Brand names: Celebrex, Elyxyb

Headaches: mentioned by 9 users (3.2%)

Based on user experiences from 280 Celecoxib reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

upset stomach 3.6%
dizziness 3.2%
headaches 3.2%
pain 3.2%
heart palpitations 2.9%
shortness of breath 2.9%
rash 2.5%
weight gain 2.5%
heartburn 2.1%
high blood pressure 1.8%

Reviews for Celecoxib

Commonly mentioned side effects
  • Orc...
  • Taken for less than 1 month
  • August 2, 2019

Celecoxib for Pain "I am on my second day of Celebrex. I was taking way too many ibuprofen every 4-6 hours for widespread osteoarthritis and skeletal-muscular pain. The first day, I was really dizzy and drowsy and spent all day in bed. Today, I am back to work, and while I feel my overall arthritis is slightly improved, the areas where I have the most swelling (ankle, knees) are not responding as well as with the ibuprofen. And areas like my back, shoulder, and hands have increased pain levels. I am having more trouble walking. I keep getting headache pain that comes and goes and causes me to feel dizzy and nauseous. I am not sure if this is typical and I just need time to adjust or not. But I find myself having trouble getting through the work day."

4 / 10
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47 Report
  • tst...
  • Taken for less than 1 month
  • February 11, 2022

Celecoxib for Pain "I know you should give medication time to work, but with this one, I couldn’t handle a third day of trying it. My dose was 100 mg, once daily. I was so hopeful that it would work out because my pain is so bad. I woke up after the first day of taking this medication and I didn’t feel well. I didn’t put it together with the medicine until I took the second dose. I felt like my stomach was going to pop from bloating, with gastric disturbances in my intestines. My head felt weird, more than just a headache. The headache came with a feeling of depression and brain fog. And fatigue? Wow, how could I keep going like this? I was miserable. Taking one more day could do me in. I wasn’t meant to keep taking it. Now I’m disappointed. I really wanted it to work. I’m happy for everyone who has extreme pain and can take this medication. It’s not easy to deal with chronic pain."

1 / 10
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24 Report
  • LJ...
  • Taken for less than 1 month
  • February 13, 2013

Celecoxib for Osteoarthritis "I was given some samples of Celebrex from my physician for wrist and hand pain. After I took the second capsule of 200 mg, I awoke in the night with an extremely bad headache, had the chills, aching muscles, runny nose, and a dry hacking cough. I stopped taking the pills, but as my symptoms persisted, I believed I had the flu. Three weeks later, I again tried Celebrex, and on the second day of taking the pills, I was again stricken with chills, a headache, nausea, and the runny nose. These symptoms have stayed with me for the past three days."

1 / 10
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70 Report

Frequently asked questions

  • Jus...
  • Taken for less than 1 month
  • January 3, 2022

Celecoxib for Pain "I had extreme stomach pain, nausea, headaches, and flatulence while on this medicine. The side effects were so great that I couldn't even tell if it was helping with the nerve pain in my legs. I am not impressed with this medication and do not plan to take it again."

1 / 10
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19 Report
  • big...
  • October 31, 2012

Celecoxib for Pain "A few years before I went through menopause. I used to have incredible pain, headache, and felt like my lymph nodes were going to burst out of my throat 3 days before my menstruation, and when I started to take this, it worked totally. I had tried all kinds of painkillers, but nothing made any difference. My doctor had prescribed it for my back pain originally. So one day, I decided to try taking it for my menstrual pain and was amazed that it worked so well for my lymph nodes and headache as well."

10 / 10
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46 Report

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  • Cal...
  • Taken for less than 1 month
  • September 6, 2019

For Pain "I was prescribed Celecoxib for psoriatic arthritis (which is an autoimmune problem). I’ve been on it for 2 weeks, and I’ve noticed a noticeable improvement in my mobility and significant decrease in swelling in my joints. I’m also on HUMIRA injections every 2 weeks. I’ve taken so many different NSAIDs over the years and had bad reactions to all of them, but so far I’m only having some headaches with Celecoxib, and they are manageable. I am using my cane less and less, and most of the time I can alternate steps going up and down, which I’ve been unable to do for years. I’m keeping my fingers crossed that I continue to improve with little to no serious side effects. I’m currently taking 100 mg B.I.D."

8 / 10
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9 Report
  • Car...
  • Taken for 2 to 5 years
  • September 10, 2022

Celecoxib for Spondyloarthritis "I relied on Celebrex for 5 years for inflammation relief. Took 200 mg daily, sometimes 400 mg. Naturally, it’s important to protect your stomach lining. Cimetidine did this job fine. Right now, I’m on a break from Celebrex. My rheumatologist is seeing lots of petechiae due to chronic use, even at 100 mg a day. It does thin the blood. After 7 days of stopping, the petechiae has faded dramatically, there is no new bruising on my body anywhere at all, something I’ve become used to seeing. I don’t have a crushing headache every day, a side effect worth the joint pain relief. But I’m in pain without it. I’m taking 1-5 mg of prednisone for now. Keeps me awake, but it’s nice to see my arms and hands look normal. Petechiae is strange. It’s red, usually one medium spot with a whole bunch of little spots sprinkled around it. They take forever to go away and come back quickly. Makes me look OLD. I still recommend this drug as needed, but maybe not every day."

7 / 10
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5 Report
  • Kik...
  • Taken for less than 1 month
  • June 23, 2020

For Rheumatoid Arthritis "My doctor ordered this medication for my rheumatoid arthritis in my back and my hands. For the pain, it's really helping me, but my heart is beating too much for a few minutes and it's gone, it's on and off, followed by cough, also dizziness and headache. I stopped taking this medicine after 4 days of taking 200 mg/day. After I talked to my doctor because of the side effects."

3 / 10
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3 Report
  • Kar...
  • Taken for less than 1 month
  • August 21, 2024

For Osteoarthritis "I had the worst headache the entire week I was on Celebrex. Went away as soon as I stopped taking it. Too bad because it really works great for arthritis pain."

5 / 10
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1 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.