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Minocin Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Minocin Spironolactone Doxycycline
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Minocin (minocycline) Spironolactone Doxycycline
Prescription only

Prescribed for Bacterial Infection, Acne, Bullous Pemphigoid, Actinomycosis, Rosacea, Meningitis - Meningococcal, Ocular Rosacea, Pemphigoid, Skin and Structure Infection, Skin or Soft Tissue... View more

Prescription only

Spironolactone is a diuretic that may be used to remove excess fluid (edema) from the body, lower blood pressure, or treat hyperaldosteronism. It does not cause potassium loss from the body; however... View more

Prescription only

Doxycycline is an effective antibiotic that treats a wide range of infections. However, it is not usually recommended for children aged less than eight or pregnant women in the last half of their... View more

More about Minocin (minocycline) More about Spironolactone More about Doxycycline
Ratings & Reviews

Minocin has an average rating of 6.8 out of 10 from a total of 22 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 16% reported a negative effect.

Spironolactone has an average rating of 6.9 out of 10 from a total of 697 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 24% reported a negative effect.

Doxycycline has an average rating of 6.4 out of 10 from a total of 1624 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 26% reported a negative effect.

View all 22 reviews

View all 697 reviews

View all 1624 reviews

Drug Class
Side Effects

See also: Minocin side effects in more detail.

See also: spironolactone side effects in more detail.

See also: doxycycline side effects in more detail.
Generic Availability

Lower cost generic approved

Lower cost generic

Lower cost generic
Pricing and Coupons * Prices are without insurance
Quantity 10 powder for injection
Dosage 100 mg
Per Unit* $265.15
Cost* $2,651.48

View all Minocin prices

Quantity 100 each
Dosage 25 mg
Per Unit* $0.22
Cost* $21.50

View all spironolactone prices

Quantity 2 tablet
Dosage hyclate 100 mg
Per Unit* $6.36
Cost* $12.71

View all doxycycline prices

Get free Discount Card

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Dosage Forms Available
  • Intravenous powder for injection
  • Oral and topical kit
  • Oral capsule
  • Oral suspension
  • Oral tablet
  • Injectable powder for injection
  • Oral capsule
  • Oral delayed release capsule
  • Oral delayed release tablet
  • Oral powder for reconstitution
  • Oral tablet
Brand Names
Other minocycline brands include: Dynacin, Minocin for Injection, Minolira, Solodyn, Ximino Aldactone, CaroSpir Acticlate, Adoxa, Adoxa CK, Adoxa Pak, Adoxa TT, Alodox, Avidoxy, Doryx, Doryx MPC, Doxy 100, Doxy 200, Doxy-Caps, Doxy-D, LymePak, Mondoxyne NL, Monodox, Morgidox, Okebo, Oracea, Oraxyl, Targadox, Uracil, Vibramycin View more
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

17.9 hours

37 hours

23 hours
CSA Schedule ** View glossary of terms
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
Pregnancy Category
D
Category D Positive evidence of risk

See the full pregnancy warnings document.
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.
D
Category D Positive evidence of risk

See the full pregnancy warnings document.
Drug Interactions

A total of 209 drugs are known to interact with Minocin:

  • 24 major drug interactions (64 brand and generic names)
  • 183 moderate drug interactions (2173 brand and generic names)
  • 2 minor drug interactions (6 brand and generic names)

A total of 383 drugs are known to interact with spironolactone:

  • 53 major drug interactions (252 brand and generic names)
  • 311 moderate drug interactions (1477 brand and generic names)
  • 19 minor drug interactions (144 brand and generic names)

A total of 209 drugs are known to interact with doxycycline:

  • 22 major drug interactions (60 brand and generic names)
  • 182 moderate drug interactions (2166 brand and generic names)
  • 5 minor drug interactions (21 brand and generic names)
Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
  • Spironolactone and alcohol may have additive effects in lowering your blood pressure. You may... View more

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
Disease Interactions
First Approval Date

N/A

January 21, 1960

December 05, 1967
WADA Class View World Anti-Doping Agency classifications.

N/A

N/A
More Information
Patient resources
Professional Resources
Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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