Comparing Methotrexate vs Sprycel
| Methotrexate | Sprycel (dasatinib) |
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| Methotrexate | Sprycel (dasatinib) |
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Prescription only
Methotrexate may be considered for the treatment of psoriasis, rheumatoid arthritis, polyarticular juvenile idiopathic arthritis (pJIA), mycosis fungoides, and certain cancers, such as ALL or... View more |
Prescription only
Sprycel is an oral tyrosine kinase inhibitor that works by inhibiting multiple conformations of the ABL kinase which is an abnormal enzyme involved in the development of blood cancers such as Ph+ CML... View more |
Related suggestions Acute Lymphoblastic Leukemia
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| More about Methotrexate | More about Sprycel (dasatinib) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Methotrexate has an average rating of 6.5 out of 10 from a total of 339 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 24% reported a negative effect. |
Sprycel has an average rating of 7.5 out of 10 from a total of 21 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 19% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Methotrexate side effects |
View all Sprycel side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Methotrexate prices |
View all Sprycel prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Jylamvo, Methotrexate LPF Sodium, Otrexup, Rasuvo, Trexall, Xatmep | Other dasatinib brands include: Phyrago | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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15 hours |
5 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 731 drugs are known to interact with Methotrexate:
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A total of 817 drugs are known to interact with Sprycel:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 07, 1953 |
June 28, 2006 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.