Comparing Methotrexate vs Sprycel
| Methotrexate Remove Methotrexate from your drug comparison | Sprycel Remove Sprycel from your drug comparison |
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| Methotrexate Remove Methotrexate from your drug comparison | Sprycel dasatinib Remove Sprycel from your drug comparison |
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Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers. Side effects can be severe and... View more |
Sprycel is an oral tyrosine kinase inhibitor that works by inhibiting multiple conformations of the ABL kinase which is an abnormal enzyme involved in the development of blood cancers such as Ph+ CML... View more |
Choose a suggestion below Acute Lymphoblastic Leukemia
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Prescription only |
Prescription only |
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Ratings & Reviews |
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Drug Class |
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Side Effects |
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Commonly reported side effects include: increased liver enzymes. See the full methotrexate side effects document. |
Common side effects include: pericardial effusion, pleural effusion, pulmonary edema, dyspnea, fluid retention, and gastrointestinal hemorrhage. See the full Sprycel side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all methotrexate prices |
View all Sprycel prices |
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Generic Availability |
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Yes (this medicine) |
No |
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Dosage Form(s) Available |
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Brand Names |
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| Methotrexate LPF Sodium, Otrexup, Rasuvo, RediTrex, Trexall, Xatmep |
N/A |
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Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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12 hours |
5 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category X
Not for use in pregnancy
See the full Pregnancy Warnings document. |
Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
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Drug Interactions |
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A total of 616 drugs are known to interact with methotrexate:
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A total of 700 drugs are known to interact with Sprycel:
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Alcohol/Food/Lifestyle Interactions |
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Disease Interactions |
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First Approval Date |
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December 07, 1953 |
June 28, 2006 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Patient resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.