Comparing Estradiol / Norethindrone vs Prempro
| Estradiol / norethindrone | Prempro (conjugated estrogens / medroxyprogesterone) |
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| Estradiol / norethindrone | Prempro (conjugated estrogens / medroxyprogesterone) |
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Prescription only
Prescribed for Atrophic Vaginitis, Postmenopausal Symptoms, Atrophic Urethritis, Hypoestrogenism. Estradiol / norethindrone may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Atrophic Vaginitis, Postmenopausal Symptoms, Atrophic Urethritis, Osteoporosis, Oophorectomy, Primary Ovarian Failure. Prempro may also be used for purposes not listed in this medication guide. View more |
Related suggestions Atrophic Vaginitis
Atrophic Urethritis
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| More about Estradiol / norethindrone | More about Prempro (conjugated estrogens / medroxyprogesterone) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Estradiol / norethindrone has an average rating of 6.5 out of 10 from a total of 99 ratings on Drugs.com. 58% of reviewers reported a positive effect, while 27% reported a negative effect. |
Prempro has an average rating of 6.9 out of 10 from a total of 67 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 24% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Prempro side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Estradiol / norethindrone prices |
View all Prempro prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Abigale, Abigale Lo, Activella, Amabelz, CombiPatch, Ena, Etyqa, Lopreeza, Mimvey, Mimvey Lo View more | Other conjugated estrogens / medroxyprogesterone brands include: Premphase, Premphase 14/14 | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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14 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 454 drugs are known to interact with Estradiol / norethindrone:
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A total of 415 drugs are known to interact with Prempro:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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November 18, 1998 |
November 17, 1995 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
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N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.