Estradiol/norethindrone Interactions
There are 454 drugs known to interact with estradiol/norethindrone, along with 23 disease interactions, and 9 alcohol/food interactions. Of the total drug interactions, 74 are major, 354 are moderate, and 26 are minor.
- View all 454 medications that may interact with estradiol/norethindrone
- View estradiol/norethindrone alcohol/food interactions (9)
- View estradiol/norethindrone disease interactions (23)
Most frequently checked interactions
View interaction reports for estradiol / norethindrone and the medicines listed below.
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- Allegra (fexofenadine)
- Ambien (zolpidem)
- Armour Thyroid (thyroid desiccated)
- Ativan (lorazepam)
- Benadryl (diphenhydramine)
- Celebrex (celecoxib)
- Claritin (loratadine)
- CoQ10 (ubiquinone)
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- Flonase (fluticasone nasal)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Mucinex (guaifenesin)
- Nexium (esomeprazole)
- Omega-3 Fish Oil (omega-3 polyunsaturated fatty acids)
- Ozempic (semaglutide)
- Paracetamol (acetaminophen)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Wellbutrin XL (bupropion)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Estradiol/norethindrone alcohol/food interactions
There are 9 alcohol/food interactions with estradiol / norethindrone.
Estradiol/norethindrone disease interactions
There are 23 disease interactions with estradiol / norethindrone which include:
- abnormal genital bleeding
- abnormal vaginal bleeding
- carcinomas (estrogenic)
- hypercalcemia in breast cancer
- hypertension
- thromboembolism/cardiovascular
- hepatic neoplasms
- breast malignancy
- liver disease
- thromboembolism
- angioedema
- gallbladder disease
- hypercalcemia
- hyperlipidemia
- liver disease
- melasma
- depression
- fluid retention
- glucose intolerance
- retinal thrombosis
- thyroid function tests
- hyperlipidemia
- weight gain
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More about estradiol / norethindrone
- estradiol/norethindrone consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (98)
- Imprints, shape & color data
- Side effects
- Dosage information
- During pregnancy
- Drug class: sex hormone combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.