Prempro and Night Sweats: What Users Say

• Liz...
• Taken for 5 to 10 years
• November 11, 2020

For Postmenopausal Symptoms "I was having night sweats, waking every hour, hot flashes, etc. Asked my doctor about HRT and decided I wanted pill form. It took about 1 month for all symptoms to go away. I have been on Prempro (lowest dose available) for 10 years and love it! I just recently had a spot on my mammogram that scared me, which turned out to be a cyst. So I decided to go off Prempro. It has been 6 weeks and I miss it. I have begun to have some hot flashes, night sweats, and headaches. My mood actually seems to have improved, but who knows? This year has been crazy for all. I want to go back on it as I felt younger, better skin, etc. As a side note, I was on birth control pills for 20 years."

• pan...
• Taken for 2 to 5 years
• October 31, 2019

For Postmenopausal Symptoms "I was 52 when I started with the night sweats. Never had any hot flashes during the day. (Thank God) The night sweats kept me up and down most nights. After sharing this with my doctor, right away I was prescribed Prempro. It was a little expensive, but worth it. I took it for three years. Throughout the years, I began to have a menstrual cycle. I can recall having one for six weeks. I was in and out of the doctor's office frequently. The final conclusion was it was a side effect of the medication. I have been off of it now for six weeks, and things are not so bad at all."

• Mcm...
• Taken for less than 1 month
• November 19, 2019

For Postmenopausal Symptoms "So I was taking Remifemin, which wasn’t working for me, so I asked my doctor about HRT. I was having severe hot flashes at night, where I was soaking wet, and hot flashes maybe 3 to 4 an hour at 48 years old, and I’ve stopped my period pretty much eight months ago. I am on my fourth day and really haven’t seen a difference in hot flashes and night sweats yet, still bloated and very sensitive, like crying at really stupid stuff... lol. I’m looking forward to seeing how this medication works, but it is awfully expensive, but thank God I can somewhat afford it."

• Anonymous
• June 1, 2017

For Postmenopausal Symptoms "I had been on Enjuvia (plus a progesterone supplement) for 3+ years, and they worked fantastic from day one! Unfortunately, they have stopped making it for reasons I can't find. I was put on Divagel, and I gained 15 pounds in 3 weeks, plus the leg (including my foot) I put it on swelled up like a balloon, among other side effects. I have been on Prempro for 6 days now, and my hot flashes/night sweats are worse than ever, but all my other 'problems' seem to be okay. The doctor's office said to give it a month, wish me luck!"

• Ano...
• Taken for 1 to 6 months
• January 1, 2025

For Postmenopausal Symptoms "I’m 54 and have been experiencing menopausal symptoms since I turned 50. After 4 years of suffering from hot flashes, night sweats, sleep deprivation, and worsening vaginal dryness/discomfort, I decided to start Prempro at the lowest dose. I’ve been on it now for about 6 months. After 2 weeks of taking it, my hot flashes and night sweats were completely gone. It was truly amazing. My sleep and my vaginal symptoms improved too. However, after about 3 - 3 1/2 months of taking it, I noticed significant hair loss. I thought my body just needed more time to adjust, so I kept taking it and my hair kept falling out, and it didn’t let up. It’s become so thin. Now I’m in the process of weaning off of Prempro because I don’t want to go bald. It’s so depressing because it was helping me in every other way. But it’s either go bald and feel good or keep my hair and feel horrible. Again, depressing."

• Mag...
• Taken for 10 years or more
• April 5, 2025

For Postmenopausal Symptoms "I feel extremely fortunate to have had a female MD at the time I hit menopause. I was 50, and my husband died around the same time menopause hit. My MD prescribed Prempro 0.3/1.5, and I believe this has kept my body healthy for the past 19 years, and yes, I am still taking Prempro today. I still maintain a healthy sex life (with my long-term partner), my bone density is good, and my overall health is very good. My gynecologist refused to prescribe this many years ago, but my PCP continues to prescribe this for me. All my friends are just now learning about the health benefits of HRT, for many, it is too late, and some prefer to use bioidentical or natural hormones. Prempro helped me through my grief, it helped with hot flashes and night sweats, and helped prevent weight gain. It is very expensive, hopefully a generic someday soon! I will reach out to Pfizer to see about some sort of discount."

• Kim...
• January 20, 2020

For Postmenopausal Symptoms "Tried every over-the-counter possible! Pharmacist said this should start working right away. Nine days in, NIGHT SWEATS still 100%. Seems I’m sleeping longer at a time. Giving it 2 months $$$$$$$."

• JCa...
• February 28, 2020

For Postmenopausal Symptoms "Ladies, breast cancer is a side effect of taking this. I would rather suffer with night sweats for the rest of my life, I cannot believe someone would take this risk knowing the facts."