Prempro and Moody: What Users Say

• Anonymous
• Taken for 5 to 10 years
• August 16, 2021

For Postmenopausal Symptoms "I have been on Prempro for 6 years. Until recently, I developed lymphadenopathy, a breast cancer in lymph and glands with no primary source in my breast or body. I have been off since this finding, as hormone replacement will feed cancer. I also had a hereditary gene study done, and it was negative. The only thing left is this caused my cancer and a very, very bad surgery… Please, ladies, don’t take this medication. I can’t stress enough-yes, it helped my mood and my hot flashes, but in the end, I’ve been going through a nightmare. Do your research! There was a 330 million dollar lawsuit against Prempro… Please stop using it! I hope this helps someone… My recovery is still ongoing, but I’m healing daily."

• Moo...
• Taken for less than 1 month
• November 4, 2018

For Postmenopausal Symptoms "I have experienced terrible hot flashes for over a year now. GYN said I was in menopause (at 51), so started on Prempro (1.5 mg) two weeks ago. Hot flashes are almost none, started my period this month after not having one in almost a year... bummer! My husband and kids say I'm more moody and not myself. I've noticed I am less tolerable (that could be my age) of things I normally would be. Also, not as hungry as normal. Overall, I feel better so far, still early."

• Anonymous
• Taken for 10 years or more
• June 7, 2022

For Postmenopausal Symptoms "I have been on Prempro for 25 years. Every time I try to wean myself off, I feel tired, moody, bones hurt, and not happy. My doctor thinks I should try weaning myself off again, my husband says, oh no... the world's not ready for that. I call it my happy pill. I’m 65, just tried again and decided if I am going to die, rather die happy than how I feel without it."

• Clo...
• Taken for less than 1 month
• March 12, 2019

For Postmenopausal Symptoms "I started the lowest dose of Prempro just 5 days ago. The GYN said it would stop/diminish the hot flashes, which in the last 5 months have been so debilitating I'm barely functioning. (Roughly every 45-90 minutes, for 8 minutes each, 24/7) I have been astonishingly moody, weepy, and fearful for the last 3 days, more than I can ever remember being since I was a teenager and new to my periods. However, I've lost most of my appetite, and although I feel 10x more stressed out inside, despite meditation and yoga, I will continue for as long as I can endure it because it's such a relief to be having fewer hot flashes. (Not gone, but maybe half as many!) However, at several hundred dollars per month for the drug, this won't last long. I figure I'll give myself a two-month break from hot flashes and then go back to suffering."