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Prempro and Acne: What Users Say

Acne: mentioned by 3 users (4.5%)

Based on user experiences from 67 Prempro reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

hot flashes 26.9%
night sweats 11.9%
weight gain 11.9%
bloating 10.4%
cramps 9.0%
hair loss 7.5%
sore breasts 7.5%
depression 6.0%
moody 6.0%
acne 4.5%

Reviews for Prempro

  • Lis...
  • October 29, 2013

"I started on Prempro on September 2, 2013, for my night sweats, hot flashes, and mood swings. I was on it for almost two months. The first month was fine, but during the second month, I developed way too many severe side effects. I had: swelling of hands and ankles, breast enlargement and pain, severe bloating, vaginal irritation, acne, my mood swings worsened, and I gained a lot of weight. The night sweats and the hot flashes got better, but the side effects were much worse than the night sweats and hot flashes. I started on Healthy Woman Soy Menopause Supplement, and it took care of the night sweats and hot flashes without all of the other side effects. This drug is definitely not for everybody, and my advice would be to listen to your body!"

1 / 10
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48 Report
  • Kat...
  • Taken for 1 to 6 months
  • May 14, 2022

For Postmenopausal Symptoms "I was lucky to not experience menopause until 55, but moderate hot flashes became annoying, so the doctor prescribed low-dose Prempro. At first, everything seemed fine, but after a couple of months, acne and weight gain ruined it for me. I was seriously waking up every couple of days with new pimples, and I've had good skin my whole life. Weight gain and bloating also started, and I've been thin my entire life. So no way I'm living with blotchy, bad skin and a pot belly to solve a few hot flashes."

3 / 10
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12 Report
  • cbe...
  • April 5, 2012

For Oophorectomy "I am 22 and underwent oophorectomy surgery following 2 massive ovarian cysts on each ovary. Right out of surgery, I was prescribed Prempro and had to take it. I experienced hot flashes for the first few days. The doctor told me that if I felt bloated, I could skip a week and I would have a small period, which I have done. I had cramps and sporadic bleeding, but the bloating never went away. I have gained a lot of weight that has been really hard to lose, and I have been on this medicine for only 3 months. I also have really bad acne all over my face that I haven't had since junior high. Once I go back to the doctors, I will be asking to try another hormone replacement therapy."

3 / 10
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24 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.