Semaglutide and Loss Of Appetite: What Users Say (Page 5)

• All...
• Taken for 1 to 6 months
• March 15, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "I took 4 shots of .25 Wegovy. The first shot had no side effects and no problems. The second shot was a little different. Mild upset stomach starting about 24 hours afterward with some stomach pain. This subsided within the third day. My appetite was suppressed, felt fuller for longer. In the third shot, I had no appetite with stomach pain that lasted two days, and also felt as if I were going to pass out. I drank orange juice and ate saltine crackers with peanut butter, which helped. The last .25 shot of Wegovy… I had lost 12 pounds by this shot. But within a day, I was projectile vomiting, upset stomach, extreme pain in my abdomen, chills, and dizziness. I was taken to the emergency room. I was diagnosed with colitis that had gone to sepsis. The doctor explained a side effect from Wegovy may cause gastrointestinal problems. Wegovy attacked my colon and in turn, sepsis formed. I will not continue this shot. So many side effects go with it. It does curve your appetite, but I would be very cautious."

• Pat...
• Taken for 1 to 6 months
• August 29, 2022

Semaglutide for Type 2 Diabetes "I have been taking this drug for about 8 weeks, starting out with the 0.25 dose and now on the 0.5 dose. I have felt miserable the whole time, with nausea similar to pregnancy and with a revulsion to most food and smells of food cooking. Definitely low energy. I have lost weight, and I haven’t had my A1C checked since I started. I will see my doctor in a couple of weeks and will be telling her that I can’t continue to live this way. I’m 75 years young and don’t want to live the rest of my years feeling bad! Unusual, hiccup-type burps, coming out of nowhere and no appetite. Convenient once-a-week administration."

• Geo...
• Taken for less than 1 month
• February 23, 2022

Semaglutide for Type 2 Diabetes "Been on Rybelsus 3 mg for 16 days. Sugars have improved somewhat already, and weight down about 5 pounds, unexpected. BUT, no appetite, stomach feels full all the time, hard to even drink enough water each day because stomach so uncomfortable. Constipation that is not very responsive to Miralax. Cold hands. Some nausea. More heartburn than usual. Increased fatigue. And the worst is: dizziness and/or vertigo and a feeling of weird fullness in my head along with tinnitus. What the heck? Given the high cost, and that I've all these effects even before going on the 7 mg dosage, I don't think it's worth it."

• CRK...
• Taken for less than 1 month
• July 16, 2021

Semaglutide for Type 2 Diabetes "My doctor gave me a sample box of 3 mg Rybelsus for T2D. I could only tolerate it for 10 days. The first thing I noticed was my appetite was gone. As days went on, I felt like I was in my first trimester of pregnancy, although I didn’t ever feel like vomiting. Continuous nausea, lack of appetite, lethargy, and horrible constipation were my friends during the time I took the drug and for about a week afterward. I ended up in the ER with terrible IBS with very painful cramps. I thought I had a blockage from no BMs for 12 days. After being off the drug for about a week, one day I woke up and the symptoms were gone (about a week after I stopped taking it). I felt like myself again. During that short time period, the pounds just started melting off me, and I only weighed 138 going into this. I dropped down to 130. I really wanted this drug to work for me. My doctor tried to prescribe Trulicity after this. No way. It’s too similar. My A1C is 8. Not sure where to go from here."

• Ann...
• Taken for 1 to 6 months
• February 27, 2025

Semaglutide for Type 2 Diabetes "For the first 4 weeks, I took a 2.5 dosage. I lost 1 pound in 4 weeks. Very unhappy. Started on point 5 on Monday, and I am feeling nauseous and have no appetite, so I hope this clears up."

• Van...
• August 4, 2022

Semaglutide for Weight Loss (Obesity/Overweight) "Expensive and worthless. I got extremely nauseous for days, unable to eat, and felt like I’d collapse from weakness, but I had no appetite."

• Gra...
• Taken for 1 to 6 months
• February 25, 2022

Semaglutide for Type 2 Diabetes "I started on 0.25 of Ozempic, and after a month, increased to 0.50. After 2 months, I had lost 20 lbs. (I was not overweight). I constantly felt nauseous, had no appetite for anything, finally vomiting at random times whether I had eaten or not. Would take a laxative suppository every week because I had no urge ever to go. It did lower my A1C, but wasn't worth the effects. The medication has been changed."

• Her...
• Taken for 1 to 6 months
• April 28, 2021

Semaglutide for Type 2 Diabetes "I am a 54-year-old overweight male who started taking Ozempic 3 months ago to help control my type 2 diabetes and to lower my A1C. For the first 3 weeks, I took a 0.25 dose weekly and felt okay. Some occasional stomach cramps and nausea. For the past 2 months, I have been taking a 0.50 dose, and side effects have gotten worse. Loss of appetite, stomach pains, feeling nauseous, and uncontrollable diarrhea while sleeping. Yes, that's right... I have been pooping the bed. On the plus side, I have lost over 20 lbs, but at quite a disgusting price to pay. Time to either quit taking this or try something else. I now understand the commercials where the people say 'O.' It's because 'O, I pooped my pants again.'"

• joa...
• Taken for 1 to 6 months
• August 15, 2020

Semaglutide for Type 2 Diabetes "Dr put me on Rybelsus since I had bad luck with Trulicity and feeling sick every time I took the shot. The first month of the dose 3mg, I noticed I never ate. I had a complete lack of appetite. I was exhausted, had weird dreams, and a constant feeling of anxiety, and sometimes insomnia. I put up with it. The second round with the 7 mg, the first day I was sicker than heck. I felt like I was on a cliff dangling, my anxiety turned into panic, rapid heartbeat, and I was unable to sleep. I stopped after day 4. I called the doctor but she never got back to me. I am debating trying to take 7mg every other day or go back to the 3mg and see if there is a difference now that it is almost out of my system. It is brutal to the body. The warnings say nothing about the feelings of anxiety or the insomnia."

• Lau...
• Taken for 1 to 6 months
• April 1, 2020

Semaglutide for Type 2 Diabetes "I have been prescribed Ozempic for weight loss secondary to type 2. I got nauseated with some loss of appetite at 0.25 mg dosage and adapted to it over a month. Lost 9 lbs in that month. I increased to 0.5 mg last Friday (it is Tuesday), and I am miserable. Non-stop nausea, burping, some pain in the stomach, constipated. I feel miserable. I am worried about the stomach pain being pancreatitis starting, so I am increasing my water. I haven't eaten in two days. I will not continue with this drug as I think this just cannot be a good thing to do to one's body."

• Anonymous
• Taken for 1 to 6 months
• July 7, 2019

Semaglutide for Type 2 Diabetes "Loved the weight loss, everything else sucked! Nausea, diarrhea, heartburn, sulfur burps, no appetite. I ended up with a nasty gallbladder that was poisoning my body. I turned septic and ended up hospitalized. The doctors, nurses, and hospital were wonderful, but my ordeal was not over. Ten days later, I had seizures and two small strokes. Had no calcium or magnesium left in my body. The most horrible experience ever! Yes, this medicine may be great. Please be vigilant about getting your blood work done on a monthly basis, especially if you are losing fluids through digestive upset. Like I said, the drug worked as far as weight loss (47 lbs) and A1C (6.6). But I came close to losing my life and am still recovering and working with my doctors to get back to a healthy life."

• Anonymous
• Taken for less than 1 month
• January 5, 2024

For Weight Loss (Obesity/Overweight) "I was only able to use 1 injection of semaglutide, the side effects hit me so bad that I couldn’t continue the medication. I got the injection on a Friday, and 2 days later, I had a seizure, which I ended up in the hospital. I had no appetite at all, but the constant headaches and nausea were too much."

• fem...
• Taken for 6 months to 1 year
• September 23, 2023

Semaglutide for Type 2 Diabetes "Serious stomach issues, cramping, bloating, severe constipation, nausea, no appetite, rashes, pain in the upper and lower bowel, gas. Loss of too much weight, no taste for food. Have had previous trouble with colitis and diverticulitis but still prescribed this medication. Only have 1 kidney and now afraid it may be damaged. I have been on this drug for approximately 7-9 months. Now worried, but the doctor is not concerned enough to take me off this medication."

• hal...
• Taken for less than 1 month
• June 4, 2023

Semaglutide for Type 2 Diabetes "The major side effects are all I got with this med, which includes upset stomach, heartburn, burping, gas, bloating, nausea, vomiting, stomach pain, loss of appetite, stomach flu symptoms, headache, dizziness, and tiredness."

• Ell...
• Taken for 1 to 6 months
• March 30, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "No weight loss, no appetite loss after 5 weeks. Disappointed."

• Txg...
• Taken for 1 to 6 months
• January 4, 2023

Semaglutide for Type 2 Diabetes "A1c crept up to 6.9. Started Rybelsus for a 30-day intro with fairly vague side effects of light nausea, constipation, and reduced appetite. Increased to regular 7 dosage and immediately side effects were extreme and awful. Constant significant nausea, abdominal discomfort, significant constipation, low energy. Almost no desire to eat, and if I did eat, even very little food caused even more discomfort that escalated. Food just sat in my stomach feeling heavy and sour. Heartburn and gas were constant. After just 5 days of a larger dose, I stopped the medication but with lingering side effects. After being off the drug for two days, I sustained immense abdominal pain like I have NEVER experienced that finally culminated in strange diarrhea. Too many intense and questionable side effects for me. Weight loss - by not being able to eat - not worth the escalating horrible side effects for me. I'll never take this drug again."

• San...
• Taken for 1 to 6 months
• December 15, 2022

Semaglutide for Cardiovascular Risk Reduction "My doctor suggested I take Ozempic to bring down my weight and lower my chances of becoming diabetic, which runs in the family. I am 67 and trying to stay healthy. Started a month ago on .25, things were okay, some nausea and decrease in appetite. Started this week on .5 and have been extremely sick, two days in and vomiting frequently. Already have acid reflux, and it is getting worse. The most embarrassing part was today, as I was walking in the street, it just came upon me, and I had to find a corner to vomit on-a horrible experience, to say the least. I want to stick it out and hope it will get better, but I'm not sure I can. My doctor projects a two-month regimen. Hopefully, I can make it, but honestly, if things do not improve on my next dose, I will not be taking it anymore. I question the high out-of-pocket cost for a drug that is causing me so much misery."

• Chr...
• Taken for 1 to 6 months
• February 24, 2020

Semaglutide for Type 2 Diabetes "I started taking this in August. It left me with a terrible taste which I could not get rid of. I was changed to the lower dosage, and it didn’t seem too bad, but it made me feel awful. Loss of appetite, I could eat a full bowl of soup. If I went out, I had to bring half my meal home. After going back to the doctor numerous times, they have taken me off it and back to Victus, which makes me feel a lot better. I no longer have that awful taste and feel better. I did get tonsil stones, which I have never had before, and I’m pleased to say they have now gone."

• cra...
• Taken for 1 to 6 months
• June 24, 2019

Semaglutide for Type 2 Diabetes "I was okay on the 0.25 mg and 0.5 mg doses of this drug, Ozempic. Then, five weeks ago, I upped to 1 mg as planned. About four weeks ago, my mood changed, and I started to get pain in my joints and bones. Achy all over and no energy. Two weeks ago, the abdominal pains, gas, diarrhea, and those awful sulfur burps arrived. I feel absolutely awful, and the doctor is convinced it is this drug increasing. No appetite either and feeling sick. Was loving the drug in the beginning, but now I feel like I've got permanent flu!"

• Poi...
• Taken for 1 to 6 months
• January 18, 2019

Semaglutide for Type 2 Diabetes "Started taking this med about a month ago and not sure I will stick with it. After 2 weeks, stomach cramping and some constipation started, but the worst of it all is the stress I am having with horrible sulfur burps. The smell is so horrible that even the smallest of burps can linger in a room for minutes, and you can really clear a room. I have had to have Febreeze Air Fresheners nearby at all times. If I feel a burp coming in the middle of the night, I literally run to the bathroom as it is really very unpleasant for my spouse and it really embarrasses me even after 27 years of marriage as it’s that bad! We just lowered my dose to 0.25 mg, but if the sulfur burps remain, that will seal the deal and I will stop it. Have lost 10 pounds over the month too as appetite is shot, and I’m not sure that’s really the best way to lose weight if you can barely eat at all."

• Wan...
• September 24, 2018

Semaglutide for Type 2 Diabetes "Started with the 0.25 dose. The next day, I had a mild sinus-type headache and loss of appetite. No food cravings, no overeating. So far, so good, right? Well, it's now 6 months later, and I've lost 36 pounds. I can hardly eat anything. I am nauseous all the time. No energy. I'm eating primarily cereal, jello, and peanut butter. My A1C is 6.7. However, I need to go off it so that I can get some nutrition in me. Miserable experience."

• Ste...
• Taken for less than 1 month
• July 23, 2025

Semaglutide for Type 2 Diabetes "Nausea and no appetite and weakness all day long. And some dizziness."

• Jer...
• Taken for 1 to 6 months
• June 20, 2023

Semaglutide for Type 2 Diabetes "It was a disaster for me. My A1C used to stay between 7.5 and 8.5, and morning fasting readings were high, like 130 to 160. Increasing Glimepiride from 4 mg up to 8 mg didn't work. My doctor started me on 3 mg/day of Rybelsus. It caused constipation, upset stomach, and a lot of burping. But morning fasting readings came down to around 100, so I was tempted to try it out. After finishing the 3 mg dose for 30 days, I started taking 7 mg/day. My symptoms worsened: constipation, loss of appetite, noisy stomach, lots of burping, GERD, and weight loss from 152 lbs to 139 lbs in just about a couple of months. I could not afford to lose any more weight. I also saw some foamy urine indicating it was affecting my kidney function too. I stopped taking Rybelsus under my doctor's advice, and since then, the constipation is gone, the burping is gone, the appetite is good, and life seems back to normal. I still need to check on my kidneys for any issues since foamy urine is still there. The last A1C was 7.9."

• Ann...
• Taken for 1 to 6 months
• April 7, 2023

Semaglutide "I started this medication on Dec 20th, 2022, 3 mg when my doctor told me I was diabetic. I weighed 206 lbs. A1C 6.5. The first month on this, I was nauseous and felt sick. At 30 days, I told him what I felt. He said, 'I am putting you on 7 mg now. Your body will get used to it.' Here I am now, 3 months later, and I am so sick. I get nauseous still, have constipation, diarrhea, and loss of appetite, and the smell of food at times is so nasty. I am constantly feeling sick, dizziness, and I feel lightheaded, always exhausted, no energy, which scares me. My A1C is lower now, 6.1. I have pretty much stopped having sweets, carbs, or anything bad. Weight loss is out of control. My current weight is 157 lbs today when I went to the doctor. I have lost 49 lbs in 4 months. I told him I can’t take this anymore. He changed me to metformin 500 mg, let’s see how this one works. This medication hurt me more than it helped me."

• MDl...
• Taken for less than 1 month
• March 16, 2023

Semaglutide for Type 2 Diabetes "Do not use this drug. I took my first and only dose and had terrible diarrhea, so bad I had to cancel several engagements. I also had vomiting after eating, no appetite, a decline in vision, and worst was a mental haziness that took over a month to recover from. My doctor called it an allergic reaction, but I don’t believe that. Even after 8 months, I still have episodes of feeling tired and hazy. I feel like I’ve aged 5 years since taking the one dose. Other than type 2 diabetes, I was in good physical condition and health. Now I have aching muscles, reduced vision, and sporadic haziness. Yes, my A1C went down temporarily, but not worth all the rest of the side effects."