Semaglutide and Constipation: What Users Say

• PAJ...
• Taken for 6 months to 1 year
• May 2, 2025

Semaglutide for Cardiovascular Risk Reduction "Started this medication last July 2024 for cardiovascular risk reduction and prediabetes. Some very mild nausea in the first two weeks and mild constipation (just eat Activia yogurt). Have lost 22 pounds so far and normal blood sugar and A1C within three months, plus lower cholesterol. No other side effects. Definitely worth it for me, but I did read these reviews ahead of time and some were scary, so I thought I would share this as it has been positive for me."

• Ano...
• Taken for 1 to 6 months
• April 9, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "No adverse side effects. Just took 8th injection and last at 0.5 mg. Next week, dosage goes to 1 mg. Down 16 pounds in 7 weeks. I was already taking Metamucil every morning, so no constipation as some have reported, but I am having less bowel movements now. I imagine I would be constipated without it. Also take Nexium daily, so heartburn really hasn't been an issue more than it already was. Started at 6 ft and 251 pounds. Was 235 today. Goal is between 180 and 200."

• Ano...
• Taken for 1 to 2 years
• April 9, 2025

Semaglutide for Type 2 Diabetes "My provider prescribed Ozempic for my type 2 diabetes and high A1C. I ended up losing 30 pounds, and my A1C dropped dramatically, along with my blood pressure and very high triglycerides. I feel so much better in general. Ozempic has been life-changing for me. I do not worry about the effects of high blood sugars on my body anymore. Diabetes comes along with heart disease, changes in eyesight and blindness, loss of limbs, neuropathy, and difficulty healing, among other things. All of those conditions are a great concern, as I have seen members of my family suffer and die due to diabetes. Ozempic changes all of that. The side effects were fairly tough, I experienced nausea, stomach pain, constipation, and a general feeling of being unwell. However, after a bit of time, my body adjusted, and the symptoms got much, much better. It was all worth it to me. I did lose my insurance at one point after taking Ozempic for about a year and a half. I am now back on it. Thankfully."

• KCF...
• Taken for 1 to 6 months
• March 25, 2025

Semaglutide for Chronic Kidney Disease "I have been on Ozempic for the past 1 1/2 months. Gradually increased from 0.25 mg for 4 weeks, then 0.5 mg since then. After reading other reviews, the best tip I found was injecting into my thigh instead of the abdomen. Mild nausea, backache, and constipation the first 2 weeks, and nothing now but the feeling of fullness soon after eating, about 75% as much as usual. I have less interest in sugary or fried foods and have lost 12 pounds, about 2 pounds a week. At 74, my Type 2 diabetes is diet-controlled with good A1C's, so my primary use is for weight loss and preserving kidney functioning. The tiny 27 gauge needle is painless, just wish I had discovered Ozempic sooner!"

• Bit...
• Taken for 6 months to 1 year
• March 23, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "I started Wegovy in April 2024. I was 193 lbs at just between 5’1”-5’2.5. I had tried everything, but food noise and the fact that being so short, the calorie intake had to be so low to lose weight. Anyway, the first thing I noticed was a bit of nausea. That went away after a few days. I have had very minimal side effects. Sometimes a little nausea, constipation, or diarrhea. Nothing to really disrupt my life. For the first time in my life, I actually can tell when I am full. My IBS has been almost non-existent. I’m more awake. I have fewer sweet cravings. The food noise is still there, but my stomach is able to signal my brain that if I eat more, I will feel sick. I have lost to date 4/2024-3/2025, 63 lbs. I am just about to hit my normal weight goal. I knew how to lose the weight. I am someone who has a very difficult time shedding the weight with exercise and diet. I am super grateful for this opportunity to prove that a drug works so well."

• Aid...
• Taken for 6 months to 1 year
• March 7, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "I’ve lost 30 lbs, and I’ve been on it for 7 months now. Currently on a maintenance dose. I experienced nausea, stomach pain, and constipation in the beginning, but no side effects now."

• Tra...
• Taken for 1 to 6 months
• February 25, 2025

Semaglutide for Type 2 Diabetes "Rybelsus has worked wonders for me. I started with the 3 mg for 1st month, then 7 mg for 3 mos. Still on my 3rd bottle, almost done. I'm 50 yrs old and weighed 271 lbs and now am at 249 lbs and lost 22 lbs; my A1C went from 8.4 to 5.3. I'm completely satisfied with my results. It really does suppress your appetite. I've had a few bouts of constipation, diarrhea, and nausea when I 1st started it. It wasn't right away either. However, there are no more side effects. I'm good over here!! Make sure you use the discount from the manufacturer online. $10/mo"

• Loc...
• Taken for 1 to 6 months
• February 17, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "I have been on Wegovy for 10 weeks and have lost 40 pounds. I’m on a 0.25 dose and haven’t had to go up yet. Losing 2-3 pounds per week. The only side effect is constipation and dry mouth right after the injection and only lasts for 10 minutes. No complaints. Love the product! My insurance refuses to cover it. The doctor filed appeals and they still refused to approve. Will continue to use it for a few months to get to my goal weight."

• Hoo...
• Taken for 1 to 6 months
• February 14, 2025

Semaglutide for Cardiovascular Risk Reduction "I wanted to lose about 45 pounds and asked my cardiologist to prescribe Wegovy because I have cardiovascular disease. I'm on a Medicare Advantage insurance, and the med was approved. I have been on it for 2.5 months and am down 25 pounds. I haven't had any noticeable side effects except insane constipation. I already had issues with that, so I take a Linzess every morning, and that does the trick. I started noticing the curbed appetite the day after my first dose. It's not as intense now, but I have zero food noise, and I just can't eat like I used to. I have had migraines for 35+ years, and I haven't had one since starting Wegovy. I don't think it's my weight loss or improved eating habits, I think it's the medication. Before I became disabled, I was a size 4 and ate very healthy, but had 12+ migraine days per month. I inject my dose in the stomach each week and have never had any reaction to the injection. Overall, I am thrilled with Wegovy so far."

• Hoo...
• Taken for 1 to 6 months
• February 13, 2025

Semaglutide for Cardiovascular Risk Reduction "I wanted to lose about 45 pounds and asked my cardiologist to prescribe Wegovy because I have cardiovascular disease. I'm on a Medicare Advantage insurance, and the med was approved. I have been on it for 2.5 months and am down 25 pounds. I haven't had any noticeable side effects except insane constipation. I already had issues with that, so I take a Linzess every morning, and that does the trick. I started noticing the curbed appetite the day after my first dose. It's not as intense now, but I have zero food noise, and I just can't eat like I used to. I have had migraines for 35+ years, and I haven't had one since starting Wegovy. I don't think it's my weight loss or improved eating habits, I think it's the medication. Before I became disabled, I was a size 4 and ate very healthy, but had 12+ migraine days per month. I inject my dose in the stomach each week and have never had any reaction to the injection. Overall, I am thrilled with Wegovy so far."

• Zee...
• Taken for 1 to 2 years
• February 7, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "70 pounds down and maintained for over a year now. Wegovy in conjunction with a high-protein, low-carb food plan does it right. I am convinced that the majority of negative outcomes are due to people just shooting the drug and making no changes to their diet. Stay off the sugar, keep your carb intake to vegetables and limited fruits only. Constipation avoided by adding a magnesium citrate supplement. (I use Calm)."

• Deb...
• Taken for 1 to 6 months
• January 25, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "Amazing, but do suffer constipation. Lost two stone in eight weeks."

• djw...
• January 24, 2025

For Weight Loss (Obesity/Overweight) "I have been on semaglutide for 10 months and lost 19 lbs. I lost quickly at first, now it is slowing down over the last 6 months. I did not feel like eating much for the first half, loss of appetite and stomachache. Now I eat and get my stomachache about 1/2 hr after eating and wish I did not eat. I have constipation and take a stool softener once a week and then a mild laxative once a month. My tastes have changed also."

• cha...
• Taken for 6 months to 1 year
• January 15, 2025

Semaglutide for Type 2 Diabetes "This is a miracle drug. It works. My numbers are within normal range, and I've lost a good amount of weight in the process. The weight loss has encouraged me to employ a healthier diet and exercise program. Because I eat plenty of fruit and vegetables, I don't experience constipation any longer. The side effects are very manageable."

• CcA...
• Taken for 1 to 6 months
• December 21, 2024

Semaglutide for Weight Loss (Obesity/Overweight) "I am a 74-year-old male who weighed 250 when I started Wegovy. I am now a week into the 2.4 mg dosage and down to 224 lbs. My appetite has declined, and I no longer crave food. I have only one side effect, and that has been constipation. It started the day I began the medication and still continues. I am taking milk of magnesia, and it helps, but still not regular as I would like. I strongly recommend this drug."

• PAC...
• Taken for 1 to 6 months
• December 19, 2024

Semaglutide for Type 2 Diabetes "I’m on my fifth dose of 0.25, with no applications other than minor constipation. Added more fiber, so softer to diet. So far, so good, no complaints. Very easy to administer."

• mov...
• Taken for less than 1 month
• October 23, 2024

Semaglutide "I am a 47-year-old woman taking Ozempic for 4 weeks now. .25 doses. I started at 300 lbs at 5.7'. Week 1 and 2, I had no side effects, week 3, I was a bit bloated and constipated. But I increased my water intake and walked for 40 mins 3 times a week, and it was gone within a few days. I lost 5 lbs in week 1 and 2, nothing week 3 (I assume due to the bloating and constipation), and another 5 lbs in week 4 for a total of 15 lbs in 4 weeks! I am very excited and motivated. I have always struggled with my weight, I was never a huge overeater, just very bad choices due to a lack of willpower! But since taking Ozempic, although I still get very small cravings, I find it so much easier to control. I can have a bag of chips in the house and just have a cup for an after-dinner snack and not go back for seconds! It is amazing! I can promise I have tried this before... many times... and it never worked! I would go back for seconds and thirds until the bag was gone! Lol. So far, worth the cost (no coverage)."

• hum...
• Taken for 1 to 6 months
• October 7, 2024

Semaglutide for Type 2 Diabetes "My doctor started me at the 0.25 mg dose for the first 2 weeks, then increased it to the 0.5 mg dose after that. Having taken the Byetta injections over 10 years ago (had to stop due to developing pancreatitis), using the Ozempic is similar, except for taking only once per week instead of taking several times a day with the Byetta. When I first started the Ozempic, I had nausea and constipation symptoms. At times, I still have some nausea, but it subsides quickly. After several weeks of being on the Ozempic, the constipation has decreased and I have developed a once-daily routine for bowel movements, which is okay by me... LOL. (Had my gallbladder out a year ago.) I have lost 14 lbs. since the start (over 4 months ago). I am still trying to regulate my diet to get the best advantage of the medication, but I work the night shift. I am happy with my Hemoglobin A1C levels, it dropped from 6.7 down to 6.2 in 1 month. Hoping it drops even further with the next lab work."

• gra...
• Taken for 1 to 6 months
• October 3, 2024

For Weight Loss (Obesity/Overweight) "Used for 3 months last year - kept weight off. Using 3 months this year. - So far lost a total of 30 lbs. Biggest side effect - constipation. Dose every 8-10 days."

• Ben...
• Taken for 6 months to 1 year
• September 21, 2024

Semaglutide for Cardiovascular Risk Reduction "Severe constipation. Regained the weight as soon as I ceased medication."

• Dut...
• Taken for 1 to 6 months
• September 6, 2024

Semaglutide for Weight Loss (Obesity/Overweight) "I'm almost 2 meters long, and when I started, I was more than 157 kg. Within 11 weeks, I lost 22 kg. Almost every week, I lost 1.5 kg and more after the big water loss. For me, it's an addition to the bigger plan. Yes, I use Wegovy (now on 1 mg), but I also go to the gym 5 times a week and add some hour-long walks to my day. And yes, I also have a strict timeframe where I have my meals. And yes, they are mostly veggies and some yogurt with some granola for some fiber. I had some side effects like heartburn, burping, constipation, and I'm more tired than before. But I think that's a normal thing to process, especially when you make the transition. If you are seriously overweight, please consider this medicine as a small part of the bigger plan!"

• Bar...
• Taken for 6 months to 1 year
• September 3, 2024

Semaglutide for Type 2 Diabetes "I had already lost 60 lb before taking Ozempic. I've been on Ozempic for about 5 months and have lost another 10 lbs (now at 220#). I have found that eating oatmeal and taking an OTC anti-diarrheal, I handle these problems very well. The good news is my A1c is now 6.3. My morning finger sticks run between 95 and 107. Once a week very easy to use. I don't even feel the injections. The bad news: recurring diarrhea, constipation, and stomach gas and belching."

• All...
• Taken for 2 to 5 years
• August 23, 2024

Semaglutide for Type 2 Diabetes "I was prescribed Ozempic because of type 2 diabetes, an overweight condition, and needing a quadruple bypass surgery. Ozempic immediately started my weight loss journey, I had a surgery wait time of 15 weeks. In that time, I lost close to 60 lbs. Post-surgery, I lost another 10 lbs. 2.5 years later, I am a happy 75-year-old male maintaining a weight of 45 to 49 lbs. My side effects are gastrointestinal, primarily. I cycle through constipation and diarrhea week by week. My appetite has been reduced, my energy has increased. I now take 0.75 mg weekly, my A1C last time was 6.4. For me, the benefit of taking Ozempic far outweighs the negatives of using the drug. This is just one person's experience, I assume that everyone has their own unique experience with this drug. I have to say that mine has been all positive."

• Dav...
• Taken for 6 months to 1 year
• August 23, 2024

Semaglutide "I started using Rybelsus in October of 2023. My starting dosage was 3 mg, and then raised to 7 mg about 4 months later. I have encountered redness, hives, and itching on my calves, scaly skin, diarrhea, constipation, nausea, cramping, and dizziness. Most of those symptoms have gone away. I take it each morning alone and do not take anything else for at least 30 minutes. When I get to work, an hour later, I take my heart and blood pressure medicine (for Afib). I gained a lot of weight for multiple reasons. The main reason was because of depression and chronic back disease. I just had lower back fusion, which has stopped my back pain. This means I can exercise now without severe pain. The good news: since I have been taking Rybelsus, I have lost 70 pounds. I now weigh 330, and by January 1, 2025, I want to be 299. It works, but does have side effects. The key is using it as directed and learning to eat smaller, healthier food portions."

• lou...
• Taken for 6 months to 1 year
• August 13, 2024

Semaglutide for Type 2 Diabetes "Truly a miracle drug! Took it for 6 months in 2023, and it changed my life!! The only side effects I had were constipation, but I'm not sure because I still have it. I also lost my taste for booze and cigarettes, which I was using quite a bit. But most of all, Ozempic changed my eating habits-no cravings, especially for the steaks and sides I used to eat three or four times a week. I started working out at the end of 6 months, my A1C dropped from 7+ to 6, blood sugar to 120 and 130. I lost 30 pounds and felt great. As my weight went down, so did all the other meds. I asked to stay on it till I lost another 15 pounds, but Kaiser and the doctor would not give it to me. They had no real reason but said it had too many side effects and I was too old (75). It was $$$ is why."