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Semaglutide User Reviews & Ratings (Page 3)

Brand names: Ozempic, Wegovy, Rybelsus

Semaglutide has an average rating of 6.9 out of 10 from a total of 2,787 reviews on Drugs.com. 56% of reviewers reported a positive experience, while 20% reported a negative experience.

Reviews for Semaglutide

Commonly mentioned side effects
  • Pad...
  • Taken for 6 months to 1 year
  • April 14, 2025

Semaglutide for Type 2 Diabetes "Started taking .25 Ozempic middle of last year. Now up to .75, which I split up by doing .25 middle of the week and .5 on the weekend - this is to combat any nausea, which I get. Also on 1500 mg Metformin. I have lost over 45 lbs, but most importantly, my blood sugars have halved, so I am down to normal range. My energy has increased, and I sleep a lot better. Blood pressure and cholesterol have also come down. I quite often make myself dinner, and then after a few mouthfuls, I don't feel like eating any more, but whereas before I used to force myself to eat it, this just doesn't happen any more, and I just push the plate away. TBH, I don't really like food like I used to. Drugs do affect everyone differently, so just have to be aware of that. I guess I was one of the lucky ones with minimal side effects."

10 / 10
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  • Ano...
  • Taken for 1 to 6 months
  • April 10, 2025

For Cardiovascular Risk Reduction "With high BP and cholesterol, my coronary artery disease resulted in 5 stents. With 169 lbs on my 5'1" frame, I knew a strike was headed my way. Have taken the GLP-1 injections for 6 months and am now at 126 lbs. Had rare, brief side effects at the beginning. Am eating healthy foods now as a new habit. Food is no longer a priority or needed for stress/mood. At 73 years, I'm almost back to my goal weight at 110 lbs. Highly recommend for my fellow seniors. Retired Slim RN."

10 / 10
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  • Ano...
  • Taken for 6 months to 1 year
  • April 10, 2025

Semaglutide "Life-changing. From an athlete's point of view, this medication really improved my overall life."

10 / 10
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Frequently asked questions

  • Ano...
  • Taken for 1 to 6 months
  • April 9, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "No adverse side effects. Just took 8th injection and last at 0.5 mg. Next week, dosage goes to 1 mg. Down 16 pounds in 7 weeks. I was already taking Metamucil every morning, so no constipation as some have reported, but I am having less bowel movements now. I imagine I would be constipated without it. Also take Nexium daily, so heartburn really hasn't been an issue more than it already was. Started at 6 ft and 251 pounds. Was 235 today. Goal is between 180 and 200."

10 / 10
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  • Ano...
  • Taken for 1 to 2 years
  • April 9, 2025

Semaglutide for Type 2 Diabetes "My provider prescribed Ozempic for my type 2 diabetes and high A1C. I ended up losing 30 pounds, and my A1C dropped dramatically, along with my blood pressure and very high triglycerides. I feel so much better in general. Ozempic has been life-changing for me. I do not worry about the effects of high blood sugars on my body anymore. Diabetes comes along with heart disease, changes in eyesight and blindness, loss of limbs, neuropathy, and difficulty healing, among other things. All of those conditions are a great concern, as I have seen members of my family suffer and die due to diabetes. Ozempic changes all of that. The side effects were fairly tough, I experienced nausea, stomach pain, constipation, and a general feeling of being unwell. However, after a bit of time, my body adjusted, and the symptoms got much, much better. It was all worth it to me. I did lose my insurance at one point after taking Ozempic for about a year and a half. I am now back on it. Thankfully."

10 / 10
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  • Nao...
  • Taken for 1 to 2 years
  • April 9, 2025

Semaglutide for Type 2 Diabetes "My A1C had gone up as high as 8.0, and my doctor kept adding medications to my arsenal of drugs to control my diabetes. I was taking so many drugs but was getting terrible side effects, including kidney stones, liver enzymes over 600, diarrhea, nausea, and finally, I was hospitalized and taken off all my drugs, but then my diabetes was out of control. Finally, my GI specialist recommended starting with Ozempic .5, and that's when everything started to change. At first, I didn't see much change in my weight loss, so my doctor raised it to 1mm. It was then that I saw my A1C go down to 7.2, and I had lost 10 pounds without trying. Now I have been taking Ozempic for over a year, and my A1C is down to 6.7, and I dropped 20 pounds. I don't have any side effects unless I overeat, which I avoid. If I overeat, I get an uncomfortable feeling in my stomach, but within a short period, it subsides. I wish my mother would have had the ability to get Ozempic 10 years ago, maybe she'd be alive today."

10 / 10
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  • Ano...
  • Taken for 1 to 6 months
  • April 7, 2025

Semaglutide for Cardiovascular Risk Reduction "It is almost magic, it reduces your appetite without leaving you wanting food. If Novo Nordisk reduces the price to make it available to everyone, this medicine could affect the health and health costs of the entire insurance industry."

10 / 10
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More FAQ

  • Ano...
  • Taken for 2 to 5 years
  • March 31, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "I have lost a tremendous amount of weight using Wegovy."

10 / 10
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  • KCF...
  • Taken for 1 to 6 months
  • March 25, 2025

Semaglutide for Chronic Kidney Disease "I have been on Ozempic for the past 1 1/2 months. Gradually increased from 0.25 mg for 4 weeks, then 0.5 mg since then. After reading other reviews, the best tip I found was injecting into my thigh instead of the abdomen. Mild nausea, backache, and constipation the first 2 weeks, and nothing now but the feeling of fullness soon after eating, about 75% as much as usual. I have less interest in sugary or fried foods and have lost 12 pounds, about 2 pounds a week. At 74, my Type 2 diabetes is diet-controlled with good A1C's, so my primary use is for weight loss and preserving kidney functioning. The tiny 27 gauge needle is painless, just wish I had discovered Ozempic sooner!"

10 / 10
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  • MJo...
  • Taken for 1 to 6 months
  • March 25, 2025

Semaglutide for Type 2 Diabetes "I took it for 3 months and was sick 2 days a week, so I stopped, but I lost 40 lbs. So I want to try again. I took my shot yesterday and have thrown up 5 times today. I want to lose more weight, but I can't stand being sick. What can I do?"

10 / 10
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  • ASB...
  • Taken for 1 to 2 years
  • March 23, 2025

For Weight Loss (Obesity/Overweight) "My last check-up shows my labs are great. My A1C is 5.5, kidney, cardiac, liver, and TSH are all great. I have lost over 55 lbs., and I feel great."

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  • Ann...
  • Taken for 1 to 6 months
  • March 23, 2025

Semaglutide for Type 2 Diabetes "I have type 2 diabetes. I have been on this medication for about 5 months and have had significant improvement in my A1C. I started at 7.2 with an average blood sugar of 147. After 3 months, my doctor was well pleased my A1C had dropped to 5.2 and average BS 116. I do have a slight issue of dizziness when standing up. Not sure if the cause could be blood sugar drops. I have a family history of diabetes and understand the damage it does to your body. I was on metformin for years and my A1C was never below 6.2. I stopped taking it after reading such bad reviews and would never take it again. I have been able to mostly control my levels with diet and moderate exercise by staying active. Currently 71 and have developed a huge sweet tooth. Sugar level was in the high 140s, so I knew I had to do something. My age goal is 110, lol, so time to get healthier. I have lost about 10 pounds in a good way. My decreased appetite has helped me control the food binges."

10 / 10
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  • Ann...
  • Taken for 1 to 6 months
  • March 23, 2025

Semaglutide for Type 2 Diabetes "I have Type 2 diabetes. I have been on this medication for about 5 months and have had significant improvement in my A1C. I started at 7.2 with an average blood sugar of 147. After 3 months, my doctor was well pleased my A1C had dropped to 5.2 and average BS 116."

10 / 10
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  • Bit...
  • Taken for 6 months to 1 year
  • March 23, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "I started Wegovy in April 2024. I was 193 lbs at just between 5’1”-5’2.5. I had tried everything, but food noise and the fact that being so short, the calorie intake had to be so low to lose weight. Anyway, the first thing I noticed was a bit of nausea. That went away after a few days. I have had very minimal side effects. Sometimes a little nausea, constipation, or diarrhea. Nothing to really disrupt my life. For the first time in my life, I actually can tell when I am full. My IBS has been almost non-existent. I’m more awake. I have fewer sweet cravings. The food noise is still there, but my stomach is able to signal my brain that if I eat more, I will feel sick. I have lost to date 4/2024-3/2025, 63 lbs. I am just about to hit my normal weight goal. I knew how to lose the weight. I am someone who has a very difficult time shedding the weight with exercise and diet. I am super grateful for this opportunity to prove that a drug works so well."

10 / 10
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  • Mar...
  • Taken for 6 months to 1 year
  • March 16, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "I've been on Wegovy since September 2024. To date, I've lost about 30 pounds. I've had very mild side effects, a little nausea occasionally, particularly the first few days after increasing dosage. I have ongoing GI issues that have made it worse a few times in the last 6 months, but nothing too serious. I was nervous about injecting myself weekly, but it has been relatively easy and painless for me. I'm finally getting clear signals to stop eating when I'm full. I used to think eating a full plate of pasta was no big deal, and now I eat less pasta in general, but if I do, I aim for no more than half, and usually it's closer to a third of a plate with the addition of a small side of non-starchy vegetables. I've been seeing a nutritionist too, and they've been so helpful in making lifelong diet changes. Right before I started taking Wegovy, I looked at the reviews on here and it nearly scared me away. I'm so glad it didn't. Wegovy has been such a helpful tool in my health journey."

10 / 10
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  • TjR...
  • Taken for 1 to 6 months
  • March 15, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "I've currently lost 12 kgs in 2 months, and due to the ongoing beneficial effects at .5, I've stayed at this dosage. However, I constantly feel dehydrated even though I'm drinking plenty of water throughout the day. The consequences are that I need to take laxatives at least once per week, or I have no bowel movements. Other than this inconvenience, all is good, and I'm still very happy with the results, which have left me feeling fitter and healthier."

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  • Ten...
  • Taken for 1 to 2 years
  • March 13, 2025

Semaglutide "Been on Ozempic & Metformin for 1 year now for weight loss. I felt a little side effects in the beginning, but nothing scary or concerning, a little diarrhea, which was fine because I suffer from IBM. I’m happy with my weight loss, starting out 198 lbs, now 150 lbs, height 5’1. My doctor said to continue taking it because when asked if I should come off, the reason why he thinks I might gain the weight back. Only complaint is the loose skin looks terrible. I wonder if I will ever be able to tighten up with exercise."

10 / 10
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  • Mer...
  • Taken for less than 1 month
  • March 13, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "I have been on this medicine for a week now. Already, I am experiencing nausea at night and loss of appetite."

10 / 10
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  • Cat...
  • Taken for 1 to 6 months
  • March 12, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "I have been on this drug for over two months, and it is fantastic. No side effects (just very mild in the first few days). I have stayed on the lowest dose of 0.25 mg so far, as I am losing weight gradually each week. I am eating healthily and keeping an eye on roughly how many calories I consume a day (this is so I don’t overeat or undereat. I want to have enough strength and energy for work and sport too). The drug is like a friend who has your back. You still enjoy food and can still feel hungry, but your appetite is reduced, as are cravings for unhealthy food. It’s a miracle! I ordered mine through Boots the Chemist, who offer a lot of helpful support and advice."

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  • Bre...
  • Taken for less than 1 month
  • March 8, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "I’ve been on Wegovy 0.025 for only 2 weeks, and I’ve lost 7 lbs. I was 245, now I’m 238. This is a miracle drug. Only side effects are a metallic taste and heartburn. I’m not going to give up. I’ve been eating Healthy Choice TV dinners and loving the high protein and low-calorie meals. I’ll chat again in 2 weeks."

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  • Aid...
  • Taken for 6 months to 1 year
  • March 7, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "I’ve lost 30 lbs, and I’ve been on it for 7 months now. Currently on a maintenance dose. I experienced nausea, stomach pain, and constipation in the beginning, but no side effects now."

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  • NEW...
  • Taken for 1 to 6 months
  • March 7, 2025

Semaglutide for Type 2 Diabetes "I started out on 0.25 once a week and then 0.5 for two more weeks. I am now at 1.0. I experienced a little nausea in the beginning, but it has subsided. I find it interesting that I don't crave salty foods and actually turn them down. I am craving salads, which I find interesting. I've lost 7 pounds in 5 weeks, and now with the increase, about a pound every two days. The best part is I am on Metformin and Janumet, with a daily blood sugar averaging 340. With the addition of Ozempic, my average blood sugar has been at 122. My A1C has dropped from 11 to 9, all in a very short time. I suffered heart failure last year, and my refraction rate is now back to normal at 55 percent. I am now experiencing some fatigue, but that could just be my body adjusting to all the meds on board. I feel I now have a brighter future ahead, especially with the normal sugar level, and am planning to do a lot of outdoor activities this summer. I've also gone back to water aerobics and have my life back."

10 / 10
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  • Joa...
  • Taken for 1 to 2 years
  • March 4, 2025

Semaglutide for Cardiovascular Risk Reduction "I haven't experienced any side effects taking Wegovy. I can say I did start my whole journey with Ozempic in August 2023, right after my hysterectomy. Switching from Ozempic to Wegovy was a great move. I have had a wonderful experience being on it, my palpitations are really under control, my blood pressure is way down, and I even lost weight that I put on during menopause. I also have had high cholesterol (which is extremely high in our genes), and my last draw was good, even my A1c is down to a 4.6 from an average of always 5.3. I'm not constantly gulping water like a fish anymore and feel great, and I don't feel swollen like a balloon 24/7. My hot flashes went away along with the mood swings, and even my IBS has not been an issue. The only problems I have had is my insurance/pre-authorization to get coverage, so that's made it very hard to be on this because it has truly changed my whole life."

10 / 10
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  • Gee...
  • Taken for 1 to 2 years
  • March 2, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "From the very beginning, I began to lose weight and felt just fine. I lost the equivalent of a preteen child. I went from 265 to 189. It took some time, but I only developed heavy dandruff or mild psoriasis. After being off of Wegovy for several months, I only regained about 8-10 lbs. It has plateaued. Would I take it again? Absolutely!"

10 / 10
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  • Kev...
  • Taken for 6 months to 1 year
  • February 26, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "I have been on Wegovy for about 8 months and have lost 71 lbs, simply counting calories and taking the shot weekly. Feel so much better."

10 / 10
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