Semaglutide User Reviews & Ratings (Page 2)
Brand names: Ozempic, Wegovy, Rybelsus
Semaglutide has an average rating of 6.9 out of 10 from a total of 2,787 reviews on Drugs.com. 56% of reviewers reported a positive experience, while 20% reported a negative experience.
Reviews for Semaglutide
- gra...
- Taken for 2 to 5 years
- May 29, 2025
Semaglutide for Type 2 Diabetes "I am older and without the strength to open the bottle. I have found if I turn it upside down and hit the bottom with a hammer a couple of times, it opens easily. After using Rybelsus a few years, I have developed more side effects, constipation, sleepiness, and nausea, but I'll work through it because this drug keeps my diabetic levels perfect."
- RAM...
- Taken for 1 to 6 months
- May 28, 2025
Semaglutide for Type 2 Diabetes "I've been taking Ozempic since the beginning of March 2025. My starting dose was 0.25 and I am now at 1.0. At the time I started, I weighed about 193 and am now weighing 156 lbs. The only side effects I seem to be dealing with and do not like are nausea, vomiting, and constipation. Ozempic has curbed my appetite considerably, as well as my liquid intake, which I don't mind since I've lost a lot of my weight. Right now, my biggest problem is finding clothes to fit me and deciding if I should keep my old clothes or donate them. I really haven't bought much in the way of new clothes in part because I don't know how much more weight I am going to lose, plus the expense of buying new clothes. My goal is to weigh somewhere between 135 and 140. My A1c is down from 8.9 to 8.1, I would like that to be lower, like 7.1."
Frequently asked questions
- Ozempic Side Effects to Watch For
- Wegovy vs Ozempic: Which is Right for You?
- Which GLP-1 drug is best for weight loss?
- Tirzepatide vs semaglutide: How do they compare?
- eig...
- Taken for 6 months to 1 year
- May 27, 2025
Semaglutide for Weight Loss (Obesity/Overweight) "It’s not always what we’re eating, it’s how we’re eating it. And honestly? That one shift changed my entire relationship with food. From age 16 to 27, I bounced between extremes: strict keto, fasting, then binge eating. My weight would fluctuate drastically, and people were constantly shocked when they saw me months later. I lived in a cycle of all-or-nothing. But something changed when I started Wegovy. Not just my appetite, but my mindset. For the first time, I wasn’t being restrictive. I wasn’t following keto. I wasn’t avoiding my “binge foods.” I was actually eating them. But this time, I was eating them differently. I’d sit down. I’d take my time. I’d actually taste the food, not shoving it in while standing in the kitchen, already thinking about the next bite. And you know what? I started losing more weight than ever. Not because I was eating “healthier” food, but because I finally stopped frantically eating. I was present. Wegovy changed my mindset!"
- Mar...
- May 26, 2025
Semaglutide for Weight Loss (Obesity/Overweight) "This is a miracle pen, started on 5/22 155 lbs today 5/26 150 lbs. No side effects except the day I took the shot, got very tired in the afternoon. Eating protein shakes, not hungry at all. Hopefully, my insurance continues to pay for it!"
- SLS...
- Taken for less than 1 month
- May 25, 2025
Semaglutide for Type 2 Diabetes "This weight loss journey has literally been a life-long one. In 2020, I had gastric bypass surgery and rebound weight gain, which is not unusual. About 49% of people regain weight. Being a caregiver for aging/Alzheimer's/dementia family and a stress/emotional eater is not good. After thinking long and hard, filtering through all the hype, and considering the pros and cons of complex medical issues, I started Ozempic with my doctors. Today is week 3 and my first dose at 0.5. The biggest change I've noticed has been how it has affected the feeling of fullness and overall eating less. Some breakthrough hunger in the afternoon, but a small healthy snack fixes that. Then I start on dinner, and by the time I'm done cooking, it's dinner time."
- Ano...
- Taken for 1 to 2 years
- May 21, 2025
Semaglutide for Weight Loss (Obesity/Overweight) "Love this drug. I’ve lost 34 lbs with very little side effects. You do have to watch what you eat, some foods, especially fried foods, make you feel horrible. I’ve been on it for 1 year, which is good because I lost slowly, not all at once. The longer you keep the weight off. You do have to change your eating habits. In the beginning, I had a lot of heartburn, but I took OTC medicine, and eventually, I no longer had this problem. I’m not a big water drinker, so I’m trying to drink more water to help with constipation. You also have to limit your alcohol intake, so 1 glass of wine at dinner, and that’s it."
More FAQ
- Can you get tirzepatide from a compounding pharmacy?
- Why am I not losing weight on Ozempic?
- Does Ozempic cause muscle loss and how to prevent it?
- How much does semaglutide cost?
- Ano...
- Taken for 1 to 6 months
- May 20, 2025
For Weight Loss (Obesity/Overweight) "This has been wonderful, I lost my weight and it has cured all my anxiety! I will take it forever. Minimal side effects, I feel very good!"
- aft...
- Taken for 1 to 6 months
- May 19, 2025
For Weight Loss (Obesity/Overweight) "Very fast-acting and accurate with mild exercise and light food as recommended by my doctor to lose weight. A way to increase hope of life as obesity catapults several medical impairments and whole life is in jeopardy."
- Ano...
- May 19, 2025
Semaglutide for Weight Loss (Obesity/Overweight) "I have lost almost 70 pounds and feel great! This has been great! Initially, I had some days I was sick to my stomach and ate a little bit, it didn’t last long."
- Mar...
- Taken for less than 1 month
- May 18, 2025
For Type 2 Diabetes "Just started this drug on 3g. I am suffering from headaches. Feel tired, hungry, missing my sugar, trying to give it up, but a reading of 7.8 makes me feel poorly. I am used to very high blood sugar, 14 to 18. I do take other drugs not associated with diabetes. This may be why I have side effects."
- Apo...
- Taken for 1 to 6 months
- May 15, 2025
Semaglutide for Weight Loss (Obesity/Overweight) "I have type two diabetes but really need weight loss! I lost fifty pounds on my own then gained it back, weighing 254 when I first started taking Ozempic at .5. I went to the doctor's office today and I lost ten pounds. It’s been a month to about two. I was shocked because I have been eating a bit and a lot of cheese; imagine if I curbed my appetite. I went up to 1 today and she said in three months at the next appointment I got, she’ll up it to the highest two. I said awesome. I really haven’t had any side effects. At times it does seem to want to curb appetite though I still eat. So I got to work on my portion size and put less stuff in me. I recommend!"
- Ran...
- Taken for 6 months to 1 year
- May 7, 2025
Semaglutide for Weight Loss (Obesity/Overweight) "I have been taking Wegovy for 8 months now. My start weight was 287 lbs, and now I am down to 230 lbs. My goal when I started was to get down to 220 lbs. I thought that would be impossible, but I am 10 lbs away from my goal, down 57 lbs and still counting. Very happy with Wegovy."
- PAJ...
- Taken for 6 months to 1 year
- May 2, 2025
Semaglutide for Cardiovascular Risk Reduction "Started this medication last July 2024 for cardiovascular risk reduction and prediabetes. Some very mild nausea in the first two weeks and mild constipation (just eat Activia yogurt). Have lost 22 pounds so far and normal blood sugar and A1C within three months, plus lower cholesterol. No other side effects. Definitely worth it for me, but I did read these reviews ahead of time and some were scary, so I thought I would share this as it has been positive for me."
- Ano...
- Taken for 1 to 6 months
- April 30, 2025
Semaglutide for Weight Loss (Obesity/Overweight) "I have had non-alcoholic fatty liver disease for 10 years. My first 5 years after diagnosis, my diet consisted of a very clean diet. Low sodium, 1000 mg per day, boneless chicken, salads, fruits, and vegetables. By year 6, after losing 20 pounds, my diet remained the same and I started gaining weight again. My last five years, I gained my 20 pounds back. I am closer to 50, do not drink alcohol, have been taking Wegovy now for 4 weeks, no symptoms or side effects. I still eat a very clean diet, I find I am full faster and for longer than in the past. I also stopped eating supper at 7:30 at night. I don’t wake up hungry in the morning and feel positive about my first 4 weeks. I also exercise by walking, take vitamin D3 and calcium, I have limited mobility for high-impact workouts because I have 8 herniated discs in my cervical spine, thoracic spine, and lumbar spine. My BMI is 35, I am 5’2” and weigh 197 pounds at the start."
- ste...
- Taken for less than 1 month
- April 30, 2025
Semaglutide "I was astonished by how quickly my appetite vanished, and it has not returned. My weight is steadily dropping because I only need one meal a day. My side effects are 1. I find myself a little headachey, nothing too severe. 2. I have a constant dry mouth. That is a bit annoying. 3. My sleep patterns are affected. Also annoying. 4. Energy levels are down. 5. My desire for alcohol is way down. That's a good thing. I'm only 2 weeks into it, but getting this hunger monkey off my back is extraordinary. I would never have thought it possible. My first meal of the day is brunch, and then that's it, I don't have any further desire for food for the day and don't even think about it."
- Ano...
- Taken for less than 1 month
- April 26, 2025
Semaglutide "Incredible that one's appetite just vanishes. Sadly, the side effects are quite dramatic. Nausea, burping, tiredness. Not such a good combination."
- Har...
- Taken for 2 to 5 years
- April 25, 2025
Semaglutide for Type 2 Diabetes "I've been using Ozempic for almost 3 years now for Type II. As far as weight loss goes, it's nothing to speak of, and for me, it's more muscular weight loss than fat weight loss, so this is not good. However, as far as getting my diabetes under control, it's been great, and that's my real benefit from it, not the weight loss."
- Ano...
- Taken for less than 1 month
- April 24, 2025
For Weight Loss (Obesity/Overweight) "2 weeks on medication, lost 10 lbs. Already, there have been no side effects."
- Pam...
- Taken for 1 to 6 months
- April 24, 2025
Semaglutide for Weight Loss (Obesity/Overweight) "I have been on Wegovy now for about 5 months. I had weighed 340 lbs when I started Wegovy. I now weigh 280 lbs, I have lost 60 lbs so far. It took me 3 years to get on Wegovy through the Veterans Affairs. I am so glad this drug has been approved. I have lymphedema, and I have hardly any swelling. My cholesterol and blood pressure are down. I am feeling proud of myself for pursuing getting on Wegovy."
- Mar...
- Taken for 1 to 6 months
- April 21, 2025
Semaglutide for Weight Loss (Obesity/Overweight) "My experience so far has been excellent. I have had side effects, but for the most part have been minor. Since being on it, it has curbed my hunger. In short, I am just not hungry. I am a little surprised that I have not lost more weight at this point, but I am still on the 0.50 dose, so, as my supportive wife says, "Baby Steps!""
- It ...
- Taken for 1 to 6 months
- April 19, 2025
Semaglutide "After 7 weeks I have lost 17 pounds. No adverse symptoms. A little dizziness once in a while."
- Ano...
- Taken for 2 to 5 years
- April 17, 2025
Semaglutide for Type 2 Diabetes "I've been on it for 3-4 years now. My blood sugars have been stable since taking the medication. The side effects are manageable with changes in diet. Gallstones are the most serious side effects I have suffered. I was lucky. No surgery, being closely monitored, and I got to go back on Ozempic. Avoid fried foods."
- She...
- Taken for 1 to 6 months
- April 17, 2025
Semaglutide for Weight Loss (Obesity/Overweight) "I am on my 10th dose of Wegovy now, and I have lost 9 kg already from 73 kg to 64 kg! I was struggling with my weight before and felt so much pain in my body. Now that I am on medication and have been losing weight, all that pain is gone. How amazing is that! My palpitations were gone too, and same with my cyst pain on the left ovary! It's been 3 months of using, and all I can say is it's working great for me! My workout routine is getting better too. Minimal side effects only, especially when I started using it for a few weeks, but it was manageable. Worth it!"
- Ano...
- Taken for 1 to 6 months
- April 14, 2025
Semaglutide for Weight Loss (Obesity/Overweight) "I’m on 0.25. I’ve been on this med for 2 months. I was at 245 and down to 219."
See also:
More about semaglutide
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- Latest FDA alerts (5)
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- During pregnancy
- Support group
- Drug class: GLP-1 Agonists (Incretin Mimetics)
- Breastfeeding
Semaglutide for Type 2 Diabetes "No problems whatsoever. Appears to assist in controlling my diabetes as well as weight level, no side effects whatsoever."