Orphengesic Alternatives Compared
| Orphengesic (aspirin / caffeine / orphenadrine) | Cyclobenzaprine | Tizanidine |
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| Orphengesic (aspirin / caffeine / orphenadrine) | Cyclobenzaprine | Tizanidine |
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Prescription only
Prescribed for Muscle Spasm, Muscle Pain. Orphengesic may also be used for purposes not listed in this medication guide. |
Prescription only
Cyclobenzaprine is a muscle relaxant that may be used short-term to treat muscle spasms caused by musculoskeletal conditions, in addition to rest and physical therapy. Sedation is a common side... View more |
Prescription only
Tizanidine may be used to reduce muscle spasms but common side effects include sleepiness, a drop in blood pressure, and a dry mouth. The dosage of tizanidine should be tailored to each person and... View more |
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| More about Orphengesic (aspirin / caffeine / orphenadrine) | More about Cyclobenzaprine | More about Tizanidine | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Be the first to share your experience with this drug. |
Cyclobenzaprine has an average rating of 6.0 out of 10 from a total of 620 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 30% reported a negative effect. |
Tizanidine has an average rating of 6.2 out of 10 from a total of 382 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 29% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||
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View all Orphengesic side effects |
View all Cyclobenzaprine side effects |
View all Tizanidine side effects |
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| Drug Class | ||||||||||||||||||
| Generic Availability | ||||||||||||||||||
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N/A |
Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Cyclobenzaprine prices |
View all Tizanidine prices |
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| Dosage Forms | ||||||||||||||||||
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N/A |
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| Brand Names | ||||||||||||||||||
| Other aspirin / caffeine / orphenadrine brands include: Norgesic, Orphengesic Forte | Amrix, Comfort Pac with Cyclobenzaprine | Ontralfy, Zanaflex | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||
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16 hours |
72 hours |
2.5 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category N
Not classified
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 756 drugs are known to interact with Orphengesic:
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A total of 452 drugs are known to interact with Cyclobenzaprine:
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A total of 652 drugs are known to interact with Tizanidine:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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May 29, 1998 |
August 26, 1977 |
November 27, 1996 |
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| WADA Class View classifications | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
| Patient Resources | ||||||||||||||||||
| Professional Resources | ||||||||||||||||||
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N/A |
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| Related Treatment Guide | ||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Zanaflex
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Soma
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Diazepam
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Baclofen
Baclofen is a muscle relaxant used to treat spasticity and muscle pain in conditions like multiple ...
Tizanidine
Tizanidine is a short-acting muscle relaxant and is used to treat spasticity. Learn about side ...
Methocarbamol
Methocarbamol is a muscle relaxant that works by blocking pain sensations. Includes methocarbamol ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.