Comparing Methotrexate vs Stelara
Methotrexate Remove Methotrexate from your drug comparison | Stelara Remove Stelara from your drug comparison |
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Methotrexate Remove Methotrexate from your drug comparison | Stelara ustekinumab Remove Stelara from your drug comparison | ||||||||||||||||
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Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers. Side effects can be severe and... View more |
Prescribed for Crohn's Disease, Psoriatic Arthritis, Ulcerative Colitis - Active, Ulcerative Colitis, Plaque Psoriasis, Psoriasis. Stelara may also be used for purposes not listed in this medication... View more |
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Prescription only |
Prescription only |
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Ratings & ReviewsRecent helpful reviews |
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6.7
For Rheumatoid Arthritis: I have been on 15mg then 20mg for two years. Then developed constant explosive diarrhea, dizziness, and confusion. Judged to be allergic, and told to stop the medication immediately. The symptoms continue...how long before it gets better? I am not taking anything for RA right now after a week off methotrexate. |
7.7
For Psoriasis: 46 year old male. Not to be overly dramatic, but I was ready to commit suicide my skin was so bad. My hands looked like I was a fire victim. My elbows and legs burned and bled constantly. My scalp would flake and drop into my eyes and all over my clothes. I was in constant pain, and my relationships were non existent. Flaky skin would drift off of me whatever I did. I was weeks away from having to leave work and go on disability, which would have been the end of the line for me. Depression set in so badly I just wanted to end it all. Then I found a new dermatologist. Everything changed. My first shot of Stelara made a difference. Nine months later, 90% clear. A few trouble spots, but my hands are CLEAR! What a life changer! For Psoriasis: I had almost disabling psoriasis for 10 years. My feet was my biggest problem area, many flare ups made it hard to even walk. I too have been on everything in the past, starting with ointments all the way to Remicade, Humira, and Enbrel with little success, mostly only helped for less than 6 months. Prednisone has almost ruined my joints, and as most of you know causes weight gain. In September 2012 I got my first injection. By December I was completely clear doing insanity workouts! Over 2 years I enjoyed a psoriasis free life and it's been great! Unfortunately, I started flaring 2 months ago, and my dermatologist put me back on prednisone as my whole body is covered again. Not sure where to go from here. |
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Drug Class |
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Side Effects |
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Commonly reported side effects include: increased liver enzymes. See the full methotrexate side effects document. |
See the full Stelara side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all methotrexate prices |
View all Stelara prices |
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Generic Availability |
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Yes (this medicine) |
No |
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Dosage Form(s) Available |
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Brand Names |
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Methotrexate LPF Sodium, Otrexup, Rasuvo, RediTrex, Trexall, Xatmep |
N/A |
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Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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12 hours |
1291.2 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category X
Not for use in pregnancy
See the full Pregnancy Warnings document. |
Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
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FDA Alerts |
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N/A |
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Drug Interactions |
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A total of 589 drugs are known to interact with methotrexate:
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A total of 364 drugs are known to interact with Stelara:
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Alcohol/Food/Lifestyle Interactions |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions |
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First Approval Date |
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December 07, 1953 |
September 25, 2009 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
For Rheumatoid Arthritis: I had taken MTX in past but it did not work out for me due to rash proplem caused by MTX so Doctor recommended Sulfasalazine and it worked out very good for about 4 years but the end of friendship came to us...Sulfasalazine was not effective anymore. I met a Doctor who practice natrual madicine also ER Dortor at the local hospital....He recommended 3 natrual Supplements for RA and pain( Turmeric, Wobenzym N, White Willow) and they are very effective (on me) and it is better than Chemical based medications. I have been off from those deadly medications for 5 months now.