Comparing Lisinopril vs Prazosin

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Lisinopril	Prazosin	Enter another drug to compare

Lisinopril

Prazosin

Prescription only

Lisinopril can be used to treat high blood pressure and heart failure, and to increase survival following a heart attack. However, lisinopril may cause a persistent, dry, hacking cough which may... View more

Prescription only

Prazosin effectively treats high blood pressure but commonly causes dizziness or lightheadedness on initiation or with a dosage increase. However, a tolerance to this effect develops on continued... View more

More about Lisinopril

More about Prazosin

Ratings & Reviews

Lisinopril has an average rating of 5.0 out of 10 from a total of 627 ratings on Drugs.com. 34% of reviewers reported a positive effect, while 44% reported a negative effect.

Prazosin has an average rating of 6.9 out of 10 from a total of 281 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 24% reported a negative effect.

View all 627 reviews

View all 281 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Cough (28.7%)
Dizziness (12.1%)
Headaches (10.2%)
Tiredness (7.5%)
Swelling (6.7%)
Fatigue (5.1%)
Pain (4.9%)

View all Lisinopril side effects

Dizziness (12.5%)
Nightmares (10.0%)
Anxiety (4.6%)
Headaches (4.6%)
Tiredness (4.6%)
Vivid dreams (4.6%)
Nausea (4.3%)

View all Prazosin side effects

Drug Class

Angiotensin Converting Enzyme Inhibitors

Antiadrenergic agents, peripherally acting

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	100 each
Strength	20 mg
Per unit^*	$0.16 - $0.21
Cost^*	$15.72 - $20.50

View all Lisinopril prices

Quantity	100 each
Strength	2 mg
Per unit^*	$1.03
Cost^*	$102.57

View all Prazosin prices

Get free Discount Card

Dosage Forms

Oral tablet

Oral capsule

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

16.4 hours

4 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category D Positive evidence of risk

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 403 drugs are known to interact with Lisinopril:

44 major drug interactions (192 brand and generic names)
329 moderate drug interactions (1554 brand and generic names)
30 minor drug interactions (231 brand and generic names)

A total of 273 drugs are known to interact with Prazosin:

9 major drug interactions (24 brand and generic names)
262 moderate drug interactions (1317 brand and generic names)
2 minor drug interactions (4 brand and generic names)

Alcohol/Food/Lifestyle Interactions

It is recommended that if you are taking lisinopril you should be advised to avoid moderately high... View more
Lisinopril and alcohol may have additive effects in lowering your blood pressure. You may... View more

Ask your doctor before using prazosin together with alcohol. Using prazosin with alcohol can lower... View more

Disease Interactions

First Approval Date

December 29, 1987

June 23, 1976

WADA Class View classifications

N/A

More Information

Patient Resources

Lisinopril uses

Prazosin uses

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Lisinopril vs Prazosin

Further information

Compare Drugs