Qbrelis

Generic name: lisinopril [ lyse-IN-oh-pril ]
Brand names: Prinivil, Qbrelis, Zestril
Drug class: Angiotensin Converting Enzyme Inhibitors

Medically reviewed by Drugs.com on Jun 26, 2023. Written by Cerner Multum.

What is Qbrelis?

Qbrelis is used alone or in combination with other medications to treat high blood pressure in adults and children at least 6 years old.

Qbrelis is also used in adults to treat congestive heart failure and to improve survival after a heart attack.

Qbrelis may also be used for purposes not listed in this medication guide.

Qbrelis side effects

Get emergency medical help if you have signs of an allergic reaction: severe stomach pain, hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Qbrelis may cause serious side effects. Call your doctor at once if you have:

• a light-headed feeling, like you might pass out;

• high blood potassium--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement;

• low white blood cell counts--fever, mouth sores, skin sores, sore throat, cough;

• kidney problems--swelling, urinating less, feeling tired or short of breath; or

• liver problems--loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects of Qbrelis may include:

• headache, dizziness;

• low blood pressure, cough; or

• chest pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

Do not use if you are pregnant. Stop using Qbrelis and tell your doctor right away if you become pregnant.

Tell your doctor about all your other medicines. Some drugs should not be used with Qbrelis.

Before taking this medicine

You should not use Qbrelis if you are allergic to it or to any other ACE (angiotensin converting enzyme) inhibitor such as captopril, fosinopril, enalapril, benazepril, moexipril, perindopril, quinapril, ramipril, or trandolapril.

Do not take Qbrelis within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).

If you have diabetes, do not take Qbrelis with any medication that contains aliskiren (a blood pressure medicine).

Do not take Qbrelis if you have a history of angioedema (severe allergic reaction).

Tell your doctor if you have ever had:

• heart disease, heart problems such as a recent heart attack;

• low blood pressure;

• low white blood cell count;

• stomach pain;

• if you are on a low-salt diet;

• diabetes;

• liver disease; or

• kidney disease (or if you are on dialysis).

You may also need to avoid taking Qbrelis with aliskiren if you have kidney disease.

Stop using this medicine and tell your doctor right away if you become pregnant. Qbrelis can cause injury or death to the unborn baby if you use the medicine during your second or third trimester.

Do not breastfeed.

How should I take Qbrelis?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

You may take Qbrelis with or without food.

Measure liquid medicine with the supplied measuring device (not a kitchen spoon).

Your blood pressure will need to be checked often and you may need frequent blood tests.

Tell your doctor if you have a planned surgery.

Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking Qbrelis. This can lead to very low blood pressure, an electrolyte imbalance, or kidney failure.

If you have high blood pressure, keep using Qbrelis even if you feel well. High blood pressure often has no symptoms.

Store tightly closed at room temperature, away from moisture and heat. Do not freeze.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Qbrelis?

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

Do not use potassium supplements or salt substitutes, unless your doctor has told you to.

Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

What other drugs will affect Qbrelis?

Qbrelis can harm your kidneys, especially if you also use certain medicines for infections, cancer, or osteoporosis.

Tell your doctor about all your other medicines, especially:

• a diuretic or "water pill" that may increase blood potassium such as spironolactone, triamterene, or amiloride;

• NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others;

• insulin or diabetes medications;

• medicine to prevent organ transplant rejection such as temsirolimus, sirolimus, or everolimus; or

• heart or blood pressure medication.

This list is not complete. Other drugs may affect Qbrelis, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Related/similar drugs

amlodipine, lisinopril, aspirin, metoprolol, losartan, furosemide, carvedilol, hydrochlorothiazide, clopidogrel, spironolactone

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Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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