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Angiotensin converting enzyme inhibitors

Other names: ACE inhibitors

What are Angiotensin converting enzyme inhibitors

Angiotensin-converting enzyme (ACE) inhibitors are a class of medicines that may be used for the treatment of high blood pressure (hypertension), heart failure, or to reduce mortality following a myocardial infarction (heart attack). They may also be used for other indications, such as slowing the progression of kidney disease in people with diabetes.

ACE inhibitors impact on the renin-angiotensin-aldosterone system (RAAS), a complex physiological system that controls fluctuations in blood pressure. ACE inhibitors specifically inhibit angiotensin-converting enzyme, an enzyme that catalyzes the conversion of angiotensin I to angiotensin II, an extremely potent vasoconstrictor (narrows blood vessels). This leads to decreased levels of angiotensin II and also lowers levels of noradrenaline and aldosterone, both of which also contribute to vasoconstriction. Another substance, called renin, is also impacted by ACE inhibitors.

Although the main effect of ACE inhibitors is thought to be on the RAAS system, they still have an effect in people with low-renin hypertension (such as those of African-American origin), although the average response to ACE inhibitors is generally lower.

ACE inhibitors differ in their duration of action and some can be administered once daily. Their blood pressure lowering effects are dose-dependent and low dosages are generally recommended when initiating therapy.

List of Angiotensin converting enzyme inhibitors:

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Drug Name DownUp( View by: Brand | Generic ) Reviews Ratings DownUp
Monopril (Pro, More...)
generic name: fosinopril
1 review
   
9.0
Capoten (Pro, More...)
generic name: captopril
0 reviews
   
8.0
Univasc (Pro, More...)
generic name: moexipril
2 reviews
   
8.0
Altace (Pro, More...)
generic name: ramipril
9 reviews
   
7.9
Zestril (Pro, More...)
generic name: lisinopril
11 reviews
   
7.7
Vasotec (Pro, More...)
generic name: enalapril
2 reviews
   
7.6
Accupril (Pro, More...)
generic name: quinapril
2 reviews
   
7.5
Mavik (Pro, More...)
generic name: trandolapril
1 review
   
6.5
Lotensin (Pro, More...)
generic name: benazepril
3 reviews
   
6.0
Prinivil (Pro, More...)
generic name: lisinopril
10 reviews
   
5.8
Aceon (Pro, More...)
generic name: perindopril
0 reviews
   
5.5
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