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Generic Name: benazepril (ben AY ze pril)
Brand Names: Lotensin

What is Lotensin?

Lotensin (benazepril) is an ACE inhibitor. ACE stands for angiotensin converting enzyme.

Lotensin is used to treat high blood pressure (hypertension).

Lotensin may also be used for purposes not listed in this medication guide.

Important information

Do not use Lotensin if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away.

You should not use Lotensin if you have ever had angioedema. Do not take benazepril within 36 hours before or after taking medicine that contains sacubatril (such as Entresto).

If you have diabetes, do not use benazepril together with any medication that contains aliskiren (such as Tekturna or Tekamlo).

Before taking this medicine

You should not use Lotensin if you are allergic to benazepril, or if:

  • you have hereditary angioedema;

  • you recently took a heart medicine called sacubatril; or

  • you have ever had a severe allergic reaction to any ACE inhibitor (captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril, trandolapril).

Do not take Lotensin within 36 hours before or after taking medicine that contains sacubatril (such as Entresto).

If you have diabetes, do not use Lotensin together with any medication that contains aliskiren (such as Tekturna or Tekamlo).

You may also need to avoid taking benazepril with aliskiren if you have kidney disease.

To make sure this medicine is safe for you, tell your doctor if you have:

  • kidney disease (or if you are on dialysis);

  • liver disease;

  • any history of heart disease; or

  • if you have had an organ transplant.

Do not use Lotensin if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. Benazepril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

Benazepril can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using this medicine.

Lotensin is not approved for use by anyone younger than 6 years old.

How should I take Lotensin?

Take Lotensin exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not use this medicine in larger or smaller amounts or for longer than recommended.

You may take Lotensin with or without food.

Drink plenty of water each day while you are taking this medication.

Your blood pressure will need to be checked often, and you may need frequent blood tests.

Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medicine. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking Lotensin.

If you need surgery, tell the surgeon ahead of time that you are using this medicine.

Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Store at room temperature away from moisture and heat.

See also: Dosage Information (in more detail)

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid?

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Benazepril can decrease sweating and you may be more prone to heat stroke.

Drinking alcohol can further lower your blood pressure and may increase certain side effects of benazepril.

Do not use salt substitutes or potassium supplements while taking this medicine, unless your doctor has told you to.

Lotensin side effects

Get emergency medical help if you have any signs of an allergic reaction to Lotensin: (hives, severe stomach pain, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;

  • little or no urinating;

  • high potassium - nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement; or

  • liver problems - stomach pain (upper right side), loss of appetite, dark urine, jaundice (yellowing of the skin or eyes).

Common Lotensin side effects may include:

  • cough;

  • headache; or

  • drowsiness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Lotensin?

Other drugs may interact with benazepril, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

  • Your pharmacist can provide more information about Lotensin.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Lotensin only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2018 Cerner Multum, Inc. Version: 13.02. Revision Date: 2017-10-02, 5:15:58 PM.