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Lotensin Side Effects

Generic name: benazepril

Medically reviewed by Last updated on Apr 10, 2022.

Note: This document contains side effect information about benazepril. Some of the dosage forms listed on this page may not apply to the brand name Lotensin.

For the Consumer

Applies to benazepril: oral tablet


Oral route (Tablet)

Discontinue benazepril hydrochloride as soon as possible when pregnancy is detected, as injury and death to the developing fetus may occur with use of drugs that act directly on the renin-angiotensin system.

Side effects requiring immediate medical attention

Along with its needed effects, benazepril (the active ingredient contained in Lotensin) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking benazepril:

Less common

  • Chills
  • cold sweats
  • confusion
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • unusual tiredness or weakness

Incidence not known

  • Arm, back, or jaw pain
  • blistering, peeling, or loosening of the skin
  • bloating or swelling of the face, arms, hands, lower legs, or feet
  • chest pain or discomfort
  • diarrhea
  • fast, irregular, pounding, or racing heartbeat or pulse
  • feeling of warmth
  • fever
  • general feeling of tiredness or weakness
  • itching
  • joint or muscle pain
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • nausea
  • rapid breathing
  • rapid weight gain
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • redness of the face, neck, arms, and occasionally, upper chest
  • skin rash
  • sore throat
  • sores, ulcers, or white spots in the mouth or on the lips
  • sweating
  • tingling of the hands or feet
  • unusual weight gain or loss

Side effects not requiring immediate medical attention

Some side effects of benazepril may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Less common

  • Cough
  • dizziness
  • sleepiness or unusual drowsiness

For Healthcare Professionals

Applies to benazepril: oral tablet


The most common side effects were headache, dizziness, somnolence, and postural dizziness.[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness, somnolence, postural dizziness

Frequency not reported: Hypertonia, paresthesia[Ref]


Rare (less than 0.1%): Decreases in hemoglobin (a low value and a decrease of 5 g/dL)

Frequency not reported: Thrombocytopenia, hemolytic anemia, eosinophilia[Ref]


Frequency not reported: Stevens-Johnson syndrome, pemphigus, dermatitis, pruritus, rash, photosensitivity, alopecia, sweating, angioedema[Ref]


Frequency not reported: Asthma, bronchitis, dyspnea, sinusitis, cough[Ref]


Frequency not reported: Uric acid increased, blood glucose increased, hyponatremia[Ref]


Frequency not reported: Flushing, electrocardiographic changes, hypotension[Ref]


Frequency not reported: Nausea, pancreatitis, constipation, gastritis, vomiting, melena[Ref]


Frequency not reported: Urinary tract infection, frequent urination, impotence, proteinuria[Ref]


Frequency not reported: Serum bilirubin increased, liver enzymes increased[Ref]


Frequency not reported: Infection[Ref]


Frequency not reported: Arthritis, arthralgia, myalgia[Ref]


Frequency not reported: Fatigue, asthenia[Ref]


Frequency not reported: Anxiety, decreased libido, insomnia, nervousness[Ref]


1. "Product Information. Lotensin (benazepril)." Ciba-Geigy Pharmaceuticals (2002):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.