Estradiol topical Alternatives Compared
| Estradiol topical | Gemtesa (vibegron) | Botox (onabotulinumtoxinA) |
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| Estradiol topical | Gemtesa (vibegron) | Botox (onabotulinumtoxinA) |
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Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis, Overactive Bladder, Dyspareunia. Estradiol topical may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Overactive Bladder. Gemtesa may also be used for purposes not listed in this medication guide. |
Prescription only
Botox is approved to treat many conditions, such as chronic migraine, involuntary muscle contractions or twitching, excessive sweating, increased saliva, and overactive bladder to name a few. Botox... View more |
Related suggestions Overactive Bladder
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| More about Estradiol topical | More about Gemtesa (vibegron) | More about Botox (onabotulinumtoxinA) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Estradiol topical has an average rating of 5.1 out of 10 from a total of 489 ratings on Drugs.com. 37% of reviewers reported a positive effect, while 45% reported a negative effect. |
Gemtesa has an average rating of 7.7 out of 10 from a total of 203 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 12% reported a negative effect. |
Botox has an average rating of 5.7 out of 10 from a total of 476 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 41% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Estradiol topical side effects |
View all Gemtesa side effects |
View all Botox side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
N/A |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Estradiol topical prices |
View all Gemtesa prices |
View all Botox prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Estrace Vaginal Cream, Estring, Imvexxy, Vagifem, Yuvafem |
N/A |
Other onabotulinumtoxinA brands include: Botox Cosmetic | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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N/A |
94 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 258 drugs are known to interact with Estradiol topical:
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A total of 147 drugs are known to interact with Gemtesa:
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A total of 120 drugs are known to interact with Botox:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
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| First Approval Date | ||||||||||||||||||||||||||
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January 31, 1984 |
December 23, 2020 |
December 09, 1991 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient Resources | ||||||||||||||||||||||||||
| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Myrbetriq
Myrbetriq (mirabegron) is used to treat overactive bladder with symptoms of frequent or urgent ...
Gemtesa
Gemtesa (vibegron) is used to treat overactive bladder symptoms (OAB) in adults or men taking ...
Premarin
Premarin is used to treat symptoms of menopause such as hot flashes, and vaginal dryness. Learn ...
Estrace
Estrace (estradiol) is used to treat symptoms of menopause such as hot flashes and vaginal dryness ...
Detrol
Detrol is used to treat overactive bladder symptoms of urinary frequency, urgency, and ...
VESIcare
Vesicare is used to treat symptoms of overactive bladder such as incontinence and frequent ...
Ditropan
Ditropan XL (oxybutynin extended release) is used to treat the symptoms of overactive bladder ...
Estradiol Patch
Estradiol Patch is used for atrophic urethritis, atrophic vaginitis, breast cancer, palliative ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.