Gemtesa Side Effects

Generic name: vibegron

Medically reviewed by Philip Thornton, DipPharm. Last updated on Jan 8, 2025.

Note: This document provides detailed information about Gemtesa.

Applies to vibegron: oral tablet Side Effects associated with vibegron. Some dosage forms listed on this page may not apply specifically to the brand name Gemtesa.

Applies to vibegron: oral tablet.

Precautions

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Urine tests may be needed to check for unwanted effects.

This medicine may increase your risk of having urinary retention (trouble passing urine or not fully emptying the bladder), especially if you have bladder blockage or when using another medicine. Check with your doctor right away if you have a decrease in urine volume, decrease in the frequency of urination, difficulty in passing urine (dribbling), or painful urination.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects of Gemtesa

Along with its needed effects, vibegron (the active ingredient contained in Gemtesa) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking vibegron:

Other side effects of Gemtesa

Some side effects of vibegron may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to vibegron: oral tablet.

General adverse events

The most common adverse reactions were headache, urinary tract infection, nasopharyngitis, diarrhea, nausea, and upper respiratory tract infection.^[Ref]

Cardiovascular

• Common (1% to 10%): Hypertension
• Uncommon (0.1% to 1%): Hot flush

In nonhypertensive patients, hypertension was defined as an average systolic blood pressure (SBP) at least 140 mmHg or diastolic BP (DBP) at least 90 mmHg on 3 assessments at 2 consecutive visits. In hypertensive patients, hypertension was defined as an average increased SBP at least 20 mmHg or DBP at least 10 mmHg on 3 assessments at 2 consecutive visits, or the start or increase in dose of antihypertensive therapy at any visit.

Dermatologic

• Uncommon (0.1% to 1%): Rash
• Postmarketing reports: Angioedema of the face and larynx, eczema

Rash included pruritic rash and erythematous rash.

Gastrointestinal

• Common (1% to 10%): Diarrhea, nausea, constipation
• Frequency not reported: Dry mouth
• Postmarketing reports: Constipation

Genitourinary

• Common (1% to 10%): Urinary tract infection, increased residual urine volume
• Uncommon (0.1% to 1%): Urinary retention
• Postmarketing reports: Urinary retention

Urinary retention included urinary straining.

Hypersensitivity

• Postmarketing reports: Hypersensitivity reactions

Hypersensitivity reactions included urticaria, pruritus, rash, and drug eruption.

Nervous system

• Common (1% to 10%): Headache

Respiratory

• Common (1% to 10%): Nasopharyngitis, upper respiratory tract infection, bronchitis

See also:

Frequently asked questions

• Can Gemtesa cause dementia?
• How long does it take for Gemtesa (vibegron) to work?
• Does Gemtesa cause high blood pressure?
• How does Gemtesa (vibegron) work?
• Can men take Gemtesa?
• What is the best time to take Gemtesa?
• Does Gemtesa have a patient assistance program?
• Can you take Gemtesa after bladder polyp removal surgery?
• Does Gemtesa (vibegron) cause weight gain?

Further information

Gemtesa side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer